Early cortical bone healing around loaded titanium implants: A histological study in the rabbit

Clinical Oral Implants Research

Volumn 20, Issue 2, 2009, Pages 126-134

  Slaets, Elke ^a   Naert, Ignace ^a   Carmeliet, Geert ^b   Duyck, Joke ^a,c  

^a CATHOLIC UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c DEPARTMENT OF IMAGING AND PATHOLOGY   (Belgium)

Author keywords

Histology; Mechanical loading; Oral implant; Rabbit

Indexed keywords

BIOMATERIAL; DENTAL ALLOY; TITANIUM; TITANIUM ALLOY (TIAL6V4); TITANIUM DIOXIDE;

ANIMAL; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; BONE REGENERATION; BONE REMODELING; BONE SCREW; CHEMISTRY; COMPARATIVE STUDY; DIAPHYSIS; MECHANICAL STRESS; OSTEOBLAST; OSTEOCLAST; OSTEOCYTE; PATHOLOGY; PERIOSTEUM; PHYSIOLOGY; RABBIT; RANDOMIZATION; SURFACE PROPERTY; TIBIA; TIME; TOOTH IMPLANTATION; WOUND HEALING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE DENSITY; BONE REMODELING; BONE SCREWS; DENTAL ALLOYS; DENTAL IMPLANTS; DIAPHYSES; MODELS, ANIMAL; OSSEOINTEGRATION; OSTEOBLASTS; OSTEOCLASTS; OSTEOCYTES; OSTEOGENESIS; PERIOSTEUM; RABBITS; RANDOM ALLOCATION; STRESS, MECHANICAL; SURFACE PROPERTIES; TIBIA; TIME FACTORS; TITANIUM; WOUND HEALING;

EID: 58449115145     PISSN: 09057161     EISSN: 16000501     Source Type: Journal    
DOI: 10.1111/j.1600-0501.2008.01623.x     Document Type: Article

References (44)

1. Abrahamsson, I., Berglundh, T., Linder, E., Lang, N.P. Lindhe, J. (2004) Early bone formation adjacent to rough and turned endosseous implant surfaces. An experimental study in the dog. Clinical Oral Implants Research 15 : 381 392.
2. Adell, R., Lekholm, U., Rockler, B. Brånemark, P.I. (1981) A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. International Journal of Oral Surgery 10 : 387 416.
3. Akagawa, Y., Hashimoto, M., Kondo, N., Satomi, K., Takata, T. Tsuru, H. (1986) Initial bone-implant interfaces of submergible and supramergible endosseous single-crystal sapphire implants. Journal of Prosthetic Dentistry 55 : 96 100.
4. Albrektsson, T., Zarb, G., Worthington, P. Eriksson, A.R. (1986) The long-term efficacy of currently used dental implants: a review and proposed criteria of success. International Journal of Oral & Maxillofacial Implants 1 : 11 25.
5. Berglundh, T., Abrahamsson, I., Lang, N.P. Lindhe, J. (2003) De novo alveolar bone formation adjacent to endosseous implants. Clinical Oral Implants Research 14 : 251 262.
6. Boabaid, F., Cerri, P.S. Katchburian, E. (2001) Apoptotic bone cells may be engulfed by osteoclasts during alveolar bone resorption in young rats. Tissue and Cell 33 : 318 325.
7. Brånemark, P.I., Adell, R., Breine, U., Hansson, B.O., Lindstrom, J. Ohlsson, A. (1969) Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scandinavian Journal of Plastic and Reconstructive Surgery 3 : 81 100.
8. Brånemark, P.I., Hansson, B.O., Adell, R., Breine, U., Lindstrom, J., Hallen, O. Ohman, A. (1977) Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scandinavian Journal of Plastic and Reconstructive Surgery Supplement 16 : 1 132.
9. Bronckers, A.L., Sasaguri, K., Cavender, A.C., D'Souza, R.N. Engelse, M.A. (2005) Expression of Runx2/Cbfa1/Pebp2alphaA during angiogenesis in postnatal rodent and fetal human orofacial tissues. Journal of Bone and Mineral Research 20 : 428 437.
10. Bronckers, A.L., Sasaguri, K. Engelse, M.A. (2003) Transcription and immunolocalization of Runx2/Cbfa1/Pebp2alphaA in developing rodent and human craniofacial tissues: further evidence suggesting osteoclasts phagocytose osteocytes. Microscopy Research and Technique 61 : 540 548.
11. Brunski, J.B., Moccia, A.F. Jr., Pollack, S.R, Korostoff, E. Trachtenberg, D.I. (1979) The influence of functional use of endosseous dental implants on the tissue-implant interface. I. Histological aspects. Journal of Dental Research 58 : 1953 1969.
12. Clelland, N.L., Lee, J.K., Bimbenet, O.C. Brantley, W.A. (1995) A three-dimensional finite element stress analysis of angled abutments for an implant placed in the anterior maxilla. Journal of Prosthodontics 4 : 95 100.
13. De Smet, E., Jaeques, S.V., Jansen, J.J., Walboomers, F., Vander Sloten, J. Naert, I.E. (2007) Effect of constant strain rate, composed of varying amplitude and frequency, of early loading on peri-implant bone (re)modeling. Journal of Clinical Periodontology 34 : 618 624.
14. De Smet, E., Jaecques, S.V., Vandamme, K., Vander Sloten, J. Naert, I. (2005) Positive effect of early loading on implant stability in the bi-cortical guinea-pig model. Clinical Oral Implants Research 16 : 402 407.
15. De Smet, E., Jaecques, S.V., Wevers, M., Jansen, J.A., Jacobs, R., Vander Sloten, J. Naert, I.E. (2006) Effect of controlled early implant loading on bone healing and bone mass in guinea pigs, as assessed by micro-CT and histology. European Journal of Oral Sciences 114 : 232 242.
16. Dhert, W.J., Thomsen, P., Blomgren, A.K., Esposito, M., Ericson, L.E. Verbout, A.J. (1998) Integration of press-fit implants in cortical bone: a study on interface kinetics. Journal of Biomedical Materials Research 41 : 574 583.
17. Duyck, J., Slaets, E., Sasaguri, K., Vandamme, K. Naert, I. (2007) Effect of intermittent loading and surface roughness on peri-implant bone formation in a bone chamber model. Journal of Clinical Periodontology 34 : 998 1006.
18. Duyck, J., Vandamme, K., Geris, L., Van Oosterwyck, H., De Cooman, M., Vander Sloten, J., Puers, R. Naert, I. (2006) The influence of micro-motion on the tissue differentiation around immediately loaded cylindrical turned titanium implants. Archives of Oral Biology 51 : 1 9.
19. Duyck, J., Van Oosterwyck, H., Vander Sloten, J., De Cooman, M., Puers, R. Naert, I. (2000) Magnitude and distribution of occlusal forces on oral implants supporting fixed prostheses: an in vivo study. Clinical Oral Implants Research 11 : 465 475.
20. Eriksson, R.A., Albrektsson, T. Magnusson, B. (1984) Assessment of bone viability after heat trauma. A histological, histochemical and vital microscopic study in the rabbit. Scandinavian Journal of Plastic and Reconstructive Surgery 18 : 261 268.
21. Fujii, N., Kusakari, H. Maeda, T. (1998) A histological study on tissue responses to titanium implantation in rat maxilla: the process of epithelial regeneration and bone reaction. Journal of Periodontology 69 : 485 495.
22. Futami, T., Fujii, N., Ohnishi, H., Taguchi, N., Kusakari, H., Oshima, H. Maeda, T. (2000) Tissue response to titanium implants in the rat maxilla: ultrastructural and histochemical observations of the bone-titanium interface. Journal of Periodontology 71 : 287 298.
23. Maniatopoulos, C., Pilliar, R.M. Smith, D.C. (1986) Threaded versus porous-surfaced designs for implant stabilization in bone-endodontic implant model. Journal of Biomedical Materials Research 20 : 1309 1333.
24. Médard, C., Ribauw, C. Chavrier, C. (2000) A histological investigation on early tissue response to titanium implants in a rat intramedullary model. Journal of Oral Implantology 26 : 238 243.
25. Meyer, U., Joos, U., Mythili, J., Stamm, T., Hohoff, A., Fillies, T., Stratmann, U. Wiesmann, H.P. (2004) Ultrastructural characterization of the implant/bone interface of immediately loaded dental implants. Biomaterials 25 : 1959 1967.
26. Meyer, U., Wiesmann, H.P., Fillies, T. Joos, U. (2003) Early tissue reaction at the interface of immediately loaded dental implants. International Journal of Oral & Maxillofacial Implants 18 : 489 499.
27. Nkenke, E., Lehner, B., Fenner, M., Roman, F.S., Thams, U., Neukam, F.W. Radespiel-Troger, M. (2005) Immediate versus delayed loading of dental implants in the maxillae of minipigs: follow-up of implant stability and implant failures. International Journal of Oral & Maxillofacial Implants 20 : 39 47.
28. Nkenke, E., Lehner, B., Weinzierl, K., Thams, U., Neugebauer, J., Steveling, H., Radespiel-Troger, M. Neukam, F.W. (2003) Bone contact, growth, and density around immediately loaded implants in the mandible of mini pigs. Clinical Oral Implants Research 14 : 312 321.
29. Noble, B.S., Stevens, H., Loveridge, N. Reeve, J. (1997) Identification of apoptotic changes in osteocytes in normal and pathological human bone. Bone 20 : 273 282.
30. Ohtsu, A., Kusakari, H., Maeda, T. Takano, Y. (1997) A histological investigation on tissue responses to titanium implants in cortical bone of the rat femur. Journal of Periodontology 68 : 270 283.
31. Piattelli, A., Corigliano, M., Scarano, A., Costigliola, G. Paolantonio, M. (1998) Immediate loading of titanium plasma-sprayed implants: an histologic analysis in monkeys. Journal of Periodontology 69 : 321 327.
32. Piattelli, A., Scarano, A. Piattelli, M. (1995) Detection of alkaline and acid phosphatases around titanium implants: a light microscopical and histochemical study in rabbits. Biomaterials 16 : 1333 1338.
33. Randow, K., Ericsson, I., Nilner, K., Petersson, A. Glantz, P.O. (1999) Immediate functional loading of Brånemark dental implants. An 18-month clinical follow-up study. Clinical Oral Implants Research 10 : 8 15.
34. Sasaguri, K., Yamauchi, M., Horiguchi, M., Tsukiniko, K., Watanabe, Y., Nozaki, N. Sato, S. (2002) Generation, characterization of pebp2αa/cbfa1 monoclonal antibody and its localization in mineralized tissues. Bulletin of Kanagawa Dental College 30 : 99 105.
35. Schultes, G. Gaggl, A. (2001) Histologic evaluation of immediate versus delayed placement of implants after tooth extraction. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology 92 : 17 22.
36. Shirakura, M., Fujii, N. Ohnishi, H. (2003) Tissue response to titanium in the rat maxilla, with special reference to the effects of surface conditions on bone formation. Clinical Oral Implants Research 14 : 687 696.
37. Slaets, E., Carmeliet, G., Naert, I. Duyck, J. (2006) Early cellular responses in cortical bone healing around unloaded titanium implants: an animal study. Journal of Periodontology 77 : 1015 1024.
38. Slaets, E., Carmeliet, G., Naert, I. Duyck, J. (2007) Early trabecular bone healing around titanium implants: a histological study in the rabbit. Journal of Periodontology 78 : 510 517.
39. Szmukler-Moncler, S., Salama, H., Reingerwirtz, Y. Dubruille, J.H. (1998) Timing of loading and effect of micromotion on bone-dental implant interface: review of experimental literature. Journal of Biomedical Materials Research 43 : 192 203.
40. Testori, T., Meltzer, A., Del Fabbro, M., Zuffetti, F., Troiano, M., Francetti, L. Weinstein, R.L. (2004) Immediate occlusal loading of osseotite implants in the lower edentulous jaw. A multicenter prospective study. Clinical Oral Implants Research 15 : 278 284.
41. Vandamme, K., Naert, I., Geris, L., Vander Sloten, J., Puers, R. Duyck, J. (2007a) Histodynamics of bone tissue formation around immediately loaded cylindrical implants in the rabbit. Clinical Oral Implants Research 18 : 471 480.
42. Vandamme, K., Naert, I., Geris, L., Vander Sloten, J., Puers, R. Duyck, J. (2007b) The effect of micromotion on the tissue response around immediately loaded roughened titanium implants in the rabbit. European Journal of Oral Sciences 115 : 21 29.
43. Vandamme, K., Naert, I., Vander Sloten, J., Puers, R. Duyck, J. (2008) Effect of implant surface roughness and loading on peri-implant bone formation. Journal of Periodontology 79 : 150 157.
44. Zarb, G.A. Jansson, T. (1985) Prosthodontic procedures. In : Brånemark, P.I., Zarb, G.A. Albrektsson, T., eds. Tissue-Integrated Prostheses: Osseointegration in Clinical Dentistry. 1st edition, 241 282. Chicago : Quintessence.