Inhibition of PI3K/Akt partially leads to the inhibition of PrP C-induced drug resistance in gastric cancer cells

FEBS Journal

Volumn 276, Issue 3, 2009, Pages 685-694

  Liang, Jie ^a   Ge, Fulin ^a   Guo, Changcun ^a   Luo, Guanhong ^a   Wang, Xin ^a   Han, Guohong ^a   Zhang, Dexin ^a   Wang, Jianhong ^a   Li, Kai ^a   Pan, Yanglin ^a   Yao, Liping ^a   Yin, Zhanxin ^a   Guo, Xuegang ^a   Wu, Kaichun ^a   Ding, Jie ^a   Fan, Daiming ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Drug resistance; Gastric cancer; P gp; PI3K Akt; Prion protein

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CELL PROTEIN; DOXORUBICIN; GLYCOPROTEIN P; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PRION PROTEIN; PROTEIN KINASE B; SMALL INTERFERING RNA; VINCRISTINE;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; RNA INTERFERENCE; STOMACH CANCER; UPREGULATION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; AGED; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MIDDLE AGED; P-GLYCOPROTEIN; PRIONS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; STOMACH NEOPLASMS;

EID: 58449110641     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06816.x     Document Type: Article

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