메뉴 건너뛰기




Volumn 77, Issue 1, 2009, Pages 419-428

SarZ promotes the expression of virulence factors and represses biofilm formation by modulating SarA and agr in Staphylococcus aureus

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA HEMOLYSIN; PROTEIN SARZ; PROTEINASE; RNA; SMAD ANCHOR FOR RECEPTOR ACTIVATION; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

EID: 58449106634     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00859-08     Document Type: Article
Times cited : (61)

References (36)
  • 1
    • 8744309111 scopus 로고    scopus 로고
    • New vector for efficient allelic replacement in naturally nontransformable, low-GC-content, gram-positive bacteria
    • Arnaud, M., A. Chastanet, and M. Debarbouille. 2004. New vector for efficient allelic replacement in naturally nontransformable, low-GC-content, gram-positive bacteria. Appl. Environ. Microbiol. 70:6887-6891.
    • (2004) Appl. Environ. Microbiol , vol.70 , pp. 6887-6891
    • Arnaud, M.1    Chastanet, A.2    Debarbouille, M.3
  • 2
    • 43049135194 scopus 로고    scopus 로고
    • Boles, B. R., and A. R. Horswill. 2008. Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog. 4:e1000052.
    • Boles, B. R., and A. R. Horswill. 2008. Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog. 4:e1000052.
  • 3
    • 1942517962 scopus 로고    scopus 로고
    • Regulation of virulence determinants in Staphylococcus aureus: Complexity and applications
    • Bronner, S., H. Monteil, and G. Prevost. 2004. Regulation of virulence determinants in Staphylococcus aureus: complexity and applications. FEMS Microbiol. Rev. 28:183-200.
    • (2004) FEMS Microbiol. Rev , vol.28 , pp. 183-200
    • Bronner, S.1    Monteil, H.2    Prevost, G.3
  • 4
    • 0038304134 scopus 로고    scopus 로고
    • Alpha-toxin is required for biofilm formation by Staphylococcus aureus
    • Caiazza, N. C., and G. A. O'Toole. 2003. Alpha-toxin is required for biofilm formation by Staphylococcus aureus. J. Bacteriol. 185:3214-3217.
    • (2003) J. Bacteriol , vol.185 , pp. 3214-3217
    • Caiazza, N.C.1    O'Toole, G.A.2
  • 5
    • 21544480015 scopus 로고    scopus 로고
    • Role of the distal sarA promoters in SarA expression in Staphylococcus aureus
    • Cheung, A. L., and A. C. Manna. 2005. Role of the distal sarA promoters in SarA expression in Staphylococcus aureus. Infect. Immun. 73:4391-4394.
    • (2005) Infect. Immun , vol.73 , pp. 4391-4394
    • Cheung, A.L.1    Manna, A.C.2
  • 6
    • 40449127154 scopus 로고    scopus 로고
    • SarA of Staphylococcus aureus binds to the sarA promoter to regulate gene expression
    • Cheung, A. L., K. Nishina, and A. C. Manna. 2008. SarA of Staphylococcus aureus binds to the sarA promoter to regulate gene expression. J. Bacteriol. 190:2239-2243.
    • (2008) J. Bacteriol , vol.190 , pp. 2239-2243
    • Cheung, A.L.1    Nishina, K.2    Manna, A.C.3
  • 8
    • 0043002239 scopus 로고    scopus 로고
    • The genomic aspect of virulence, sepsis, and resistance to killing mechanisms in Staphylococcus aureus
    • Cheung, A. L., S. J. Projan, and H. Gresham. 2002. The genomic aspect of virulence, sepsis, and resistance to killing mechanisms in Staphylococcus aureus. Curr. Infect. Dis. Rep. 4:400-410.
    • (2002) Curr. Infect. Dis. Rep , vol.4 , pp. 400-410
    • Cheung, A.L.1    Projan, S.J.2    Gresham, H.3
  • 9
    • 0033601339 scopus 로고    scopus 로고
    • SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation
    • Chien, Y., A. C. Manna, S. J. Projan, and A. L. Cheung. 1999. SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation. J. Biol. Chem. 274:37169-37176.
    • (1999) J. Biol. Chem , vol.274 , pp. 37169-37176
    • Chien, Y.1    Manna, A.C.2    Projan, S.J.3    Cheung, A.L.4
  • 10
    • 0027472047 scopus 로고
    • Evolution of the alpha-crystallin/small heat-shock protein family
    • de Jong, W. W., J. A. Leunissen, and C. E. Voorter. 1993. Evolution of the alpha-crystallin/small heat-shock protein family. Mol. Biol. Evol. 10:103-126.
    • (1993) Mol. Biol. Evol , vol.10 , pp. 103-126
    • de Jong, W.W.1    Leunissen, J.A.2    Voorter, C.E.3
  • 12
    • 28644448159 scopus 로고    scopus 로고
    • The genetics of staphylococcal biofilm formation-will a greater understanding of pathogenesis lead to better management of device-related infection?
    • Fitzpatrick, F., H. Humphreys, and J. P. O'Gara. 2005. The genetics of staphylococcal biofilm formation-will a greater understanding of pathogenesis lead to better management of device-related infection? Clin. Microbiol. Infect. 11:967-973.
    • (2005) Clin. Microbiol. Infect , vol.11 , pp. 967-973
    • Fitzpatrick, F.1    Humphreys, H.2    O'Gara, J.P.3
  • 14
    • 33746561248 scopus 로고    scopus 로고
    • Inhibition of rot translation by RNAIII, a key feature of agr function
    • Geisinger, E., R. P. Adhikari, R. Jin, H. F. Ross, and R. P. Novick. 2006. Inhibition of rot translation by RNAIII, a key feature of agr function. Mol. Microbiol. 61:1038-1048.
    • (2006) Mol. Microbiol , vol.61 , pp. 1038-1048
    • Geisinger, E.1    Adhikari, R.P.2    Jin, R.3    Ross, H.F.4    Novick, R.P.5
  • 15
    • 0036771636 scopus 로고    scopus 로고
    • sigmaB modulates virulence determinant expression and stress resistance: Characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4
    • Horsburgh, M. J., J. L. Aish, I. J. White, L. Shaw, J. K. Lithgow, and S. J. Foster. 2002. sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J. Bacteriol. 184:5457-5467.
    • (2002) J. Bacteriol , vol.184 , pp. 5457-5467
    • Horsburgh, M.J.1    Aish, J.L.2    White, I.J.3    Shaw, L.4    Lithgow, J.K.5    Foster, S.J.6
  • 16
    • 15544372331 scopus 로고    scopus 로고
    • Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus
    • Ingavale, S., W. van Wamel, T. T. Luong, C. Y. Lee, and A. L. Cheung. 2005. Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus. Infect. Immun. 73:1423-1431.
    • (2005) Infect. Immun , vol.73 , pp. 1423-1431
    • Ingavale, S.1    van Wamel, W.2    Luong, T.T.3    Lee, C.Y.4    Cheung, A.L.5
  • 18
    • 33751364085 scopus 로고    scopus 로고
    • Novel DNA binding protein SarZ contributes to virulence in Staphylococcus aureus
    • Kaito, C., D. Morishita, Y. Matsumoto, K. Kurokawa, and K. Sekimizu. 2006. Novel DNA binding protein SarZ contributes to virulence in Staphylococcus aureus. Mol. Microbiol. 62:1601-1617.
    • (2006) Mol. Microbiol , vol.62 , pp. 1601-1617
    • Kaito, C.1    Morishita, D.2    Matsumoto, Y.3    Kurokawa, K.4    Sekimizu, K.5
  • 19
    • 0042743989 scopus 로고    scopus 로고
    • Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus
    • Kupferwasser, L. I., M. R. Yeaman, C. C. Nast, D. Kupferwasser, Y. Q. Xiong, M. Palma, A. L. Cheung, and A. S. Bayer. 2003. Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus. J. Clin. Investig. 112:222-233.
    • (2003) J. Clin. Investig , vol.112 , pp. 222-233
    • Kupferwasser, L.I.1    Yeaman, M.R.2    Nast, C.C.3    Kupferwasser, D.4    Xiong, Y.Q.5    Palma, M.6    Cheung, A.L.7    Bayer, A.S.8
  • 20
    • 0035139982 scopus 로고    scopus 로고
    • Characterization of sarR, a modulator of sar expression in Staphylococcus aureus
    • Manna, A., and A. L. Cheung. 2001. Characterization of sarR, a modulator of sar expression in Staphylococcus aureus. Infect. Immun. 69:885-896.
    • (2001) Infect. Immun , vol.69 , pp. 885-896
    • Manna, A.1    Cheung, A.L.2
  • 21
    • 0031829309 scopus 로고    scopus 로고
    • Transcriptional analysis of different promoters in the sar locus in Staphylococcus aureus
    • Manna, A. C., M. G. Bayer, and A. L. Cheung. 1998. Transcriptional analysis of different promoters in the sar locus in Staphylococcus aureus. J. Bacteriol. 180:3828-3836.
    • (1998) J. Bacteriol , vol.180 , pp. 3828-3836
    • Manna, A.C.1    Bayer, M.G.2    Cheung, A.L.3
  • 22
    • 33745266080 scopus 로고    scopus 로고
    • Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus
    • Manna, A. C., and A. L. Cheung. 2006. Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus. Mol. Microbiol. 60:1289-1301.
    • (2006) Mol. Microbiol , vol.60 , pp. 1289-1301
    • Manna, A.C.1    Cheung, A.L.2
  • 23
    • 0037898952 scopus 로고    scopus 로고
    • Autoinduction and signal transduction in the regulation of staphylococcal virulence
    • Novick, R. P. 2003. Autoinduction and signal transduction in the regulation of staphylococcal virulence. Mol. Microbiol. 48:1429-1449.
    • (2003) Mol. Microbiol , vol.48 , pp. 1429-1449
    • Novick, R.P.1
  • 25
    • 0142106391 scopus 로고    scopus 로고
    • The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing
    • Novick, R. P., and D. Jiang. 2003. The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing. Microbiology 149: 2709-2717.
    • (2003) Microbiology , vol.149 , pp. 2709-2717
    • Novick, R.P.1    Jiang, D.2
  • 26
    • 22544461046 scopus 로고    scopus 로고
    • Regulatory role of proteins binding to the spa (protein A) and sarS (staphylococcal accessory regulator) promoter regions in Staphylococcus aureus NTCC 8325-4
    • Oscarsson, J., C. Harlos, and S. Arvidson. 2005. Regulatory role of proteins binding to the spa (protein A) and sarS (staphylococcal accessory regulator) promoter regions in Staphylococcus aureus NTCC 8325-4. Int. J. Med. Microbiol. 295:253-266.
    • (2005) Int. J. Med. Microbiol , vol.295 , pp. 253-266
    • Oscarsson, J.1    Harlos, C.2    Arvidson, S.3
  • 27
    • 33845388892 scopus 로고    scopus 로고
    • SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: Its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS
    • Oscarsson, J., A. Kanth, K. Tegmark-Wisell, and S. Arvidson. 2006. SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS. J. Bacteriol. 188:8526-8533.
    • (2006) J. Bacteriol , vol.188 , pp. 8526-8533
    • Oscarsson, J.1    Kanth, A.2    Tegmark-Wisell, K.3    Arvidson, S.4
  • 28
    • 33748457563 scopus 로고    scopus 로고
    • Coordinated and differential control of aureolysin (aur) and serine protease (sspA) transcription in Staphylococcus aureus by sarA, rot and agr (RNAIII)
    • Oscarsson, J., K. Tegmark-Wisell, and S. Arvidson. 2006. Coordinated and differential control of aureolysin (aur) and serine protease (sspA) transcription in Staphylococcus aureus by sarA, rot and agr (RNAIII). Int. J. Med. Microbiol. 296:365-380.
    • (2006) Int. J. Med. Microbiol , vol.296 , pp. 365-380
    • Oscarsson, J.1    Tegmark-Wisell, K.2    Arvidson, S.3
  • 30
    • 58449084047 scopus 로고    scopus 로고
    • Rasband, W. S. 2007. ImageJ. National Institutes of Health, Bethesda, MD.
    • Rasband, W. S. 2007. ImageJ. National Institutes of Health, Bethesda, MD.
  • 31
    • 0026891517 scopus 로고
    • Improved method for electroporation of Staphylococcus aureus
    • Schenk, S., and R. A. Laddaga. 1992. Improved method for electroporation of Staphylococcus aureus. FEMS Microbiol. Lett. 73:133-138.
    • (1992) FEMS Microbiol. Lett , vol.73 , pp. 133-138
    • Schenk, S.1    Laddaga, R.A.2
  • 32
    • 0034911684 scopus 로고    scopus 로고
    • SarT, a repressor of alpha-hemolysin in Staphylococcus aureus
    • Schmidt, K. A., A. C. Manna, S. Gill, and A. L. Cheung. 2001. SarT, a repressor of alpha-hemolysin in Staphylococcus aureus. Infect. Immun. 69: 4749-4758.
    • (2001) Infect. Immun , vol.69 , pp. 4749-4758
    • Schmidt, K.A.1    Manna, A.C.2    Gill, S.3    Cheung, A.L.4
  • 33
    • 23644457820 scopus 로고    scopus 로고
    • SarA positively controls bap-dependent biofilm formation in Staphylococcus aureus
    • Trotonda, M. P., A. C. Manna, A. L. Cheung, I. Lasa, and J. R. Penades. 2005. SarA positively controls bap-dependent biofilm formation in Staphylococcus aureus. J. Bacteriol. 187:5790-5798.
    • (2005) J. Bacteriol , vol.187 , pp. 5790-5798
    • Trotonda, M.P.1    Manna, A.C.2    Cheung, A.L.3    Lasa, I.4    Penades, J.R.5
  • 34
    • 57349170726 scopus 로고    scopus 로고
    • Trotonda, M. P., S. Tamber, G. Memmi, and A. L. Cheung. 13 October 2008, posting date. MgrA represses biofilm formation in Staphylococcus aureus. Infect. Immun. [Epub ahead of print.]
    • Trotonda, M. P., S. Tamber, G. Memmi, and A. L. Cheung. 13 October 2008, posting date. MgrA represses biofilm formation in Staphylococcus aureus. Infect. Immun. [Epub ahead of print.]
  • 35
    • 0026010391 scopus 로고
    • A temporal signal, independent of agr, is required for hla but not spa transcription in Staphylococcus aureus
    • Vandenesch, F., J. Kornblum, and R. P. Novick. 1991. A temporal signal, independent of agr, is required for hla but not spa transcription in Staphylococcus aureus. J. Bacteriol. 173:6313-6320.
    • (1991) J. Bacteriol , vol.173 , pp. 6313-6320
    • Vandenesch, F.1    Kornblum, J.2    Novick, R.P.3
  • 36
    • 33750294761 scopus 로고    scopus 로고
    • Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae in vitro and in experimental infective endocarditis
    • Xiong, Y. Q., J. Willard, M. R. Yeaman, A. L. Cheung, and A. S. Bayer. 2006. Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae in vitro and in experimental infective endocarditis. J. Infect. Dis. 194:1267-1275.
    • (2006) J. Infect. Dis , vol.194 , pp. 1267-1275
    • Xiong, Y.Q.1    Willard, J.2    Yeaman, M.R.3    Cheung, A.L.4    Bayer, A.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.