Peritoneal morphological and functional changes associated with platelet-derived growth factor B

Nephrology Dialysis Transplantation

Volumn 24, Issue 2, 2009, Pages 448-457

  Cina, Davide ^a   Patel, Pranali ^a   Bethune, Jessica C ^a   Thoma, Jessica ^a   Rodriguez Lecompte, Juan Carlos ^b   Hoff, Catherine M ^c   Liu, Limin ^a   Margetts, Peter J ^a,d  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c BAXTER HEALTHCARE CORPORATION   (United States)

^d NONE   (Canada)

Author keywords

Adenovirus; Angiogenesis; Fibrosis; Peritoneal dialysis; Platelet derived growth factor

Indexed keywords

ADENOVIRUS VECTOR; COLLAGEN; HYDROXYPROLINE; PLATELET DERIVED GROWTH FACTOR B; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FIBROSIS; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; MESOTHELIUM CELL; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PERITONEAL DISEASE; PERITONEUM; PRIORITY JOURNAL; RAT; ULTRAFILTRATION;

ADENOVIRIDAE; ANIMALS; COLLAGEN; EPITHELIUM; GENE EXPRESSION; GENES, SIS; GENETIC VECTORS; HUMANS; MESODERM; NEOVASCULARIZATION, PATHOLOGIC; PERITONEAL DIALYSIS; PERITONEUM; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA1;

EID: 58449102439     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfn498     Document Type: Article

References (31)

1. Williams JD, Craig KJ, Topley N et al. Peritoneal Biopsy Study Group Morphologic changes in the peritoneal membrane of patients with renal disease. J Am Soc Nephrol 2002; 13: 470-479
2. Davies SJ. Longitudinal relationship between solute transport and ultrafiltration capacity in peritoneal dialysis patients. Kidney Int 2004; 66: 2437-2445
3. Margetts PJ, Churchill DN. Acquired ultrafiltration dysfunction in peritoneal dialysis patients. J Am Soc Nephrol 2002; 13: 2787-2794
4. Krediet RT, Lindholm B, Rippe B. Pathophysiology of peritoneal membrane failure. [Review] [153 refs]. Perit Dial Int 2000; 20 (Suppl 4): S22-S42
5. Flessner MF. The transport barrier in intraperitoneal therapy. Am J Physiol Renal Physiol 2005; 288: F433-F442
6. Yanez-Mo M, Lara-Pezzi E, Selgas R et al. Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells. N Engl J Med 2003; 348: 403-413
7. Margetts PJ, Brimble KS. Peritoneal dialysis, membranes and beyond. Curr Opin Nephrol Hypertens 2006; 15: 571-576
8. Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 1999; 79: 1283-1316
9. Matsui T, Pierce JH, Fleming TP et al. Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways. Proc Natl Acad Sci USA 1989; 86: 8314-8318
10. Tang WW, Ulich TR, Lacey DL et al. Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis. Am J Pathol 1996; 148: 1169-1180
11. Yang C, Zeisberg M, Mosterman B et al. Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology 2003; 124: 147-159
12. Yi ES, Lee H, Yin S et al. Platelet-derived growth factor causes pulmonary cell proliferation and collagen deposition in vivo. Am J Pathol 1996; 149: 539-548
13. Isaka Y, Fujiwara Y, Ueda N et al. Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney. J Clin Invest 1993; 92: 2597-2601
14. Fraser D, Wakefield L, Phillips A. Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. Am J Pathol 2002; 161: 1039-1049
15. Hosang M, Rouge M, Wipf B et al. Both homodimeric isoforms of PDGF (AA and BB) have mitogenic and chemotactic activity and stimulate phosphoinositol turnover. J Cell Physiol 1989; 140: 558-564
16. Hellstrom M, Gerhardt H, Kalen M et al. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol 2001; 153: 543-553
17. Margetts PJ, Bonniaud P, Liu L et al. Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum. J Am Soc Nephrol 2005; 16: 425-436
18. Beavis MJ, Williams JD, Hoppe J et al. Human peritoneal fibroblast proliferation in 3-dimensional culture: modulation by cytokines, growth factors and peritoneal dialysis effluent. Kidney Int 1997; 51: 205-215
19. Lai KN, Lai KB, Szeto CC et al. Growth factors in continuous ambulatory peritoneal dialysis effluent. Their relation with peritoneal transport of small solutes. Am J Nephrol 1999; 19: 416-422
20. Bonner JC. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev 2004; 15: 255-273
21. Daniels CE, Wilkes MC, Edens M et al. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis. J Clin Invest 2004; 114: 1308-1316
22. Xing Z, Ohkawara Y, Jordana M et al. Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions. J Clin Invest 1996; 97: 1102-1110
23. Margetts PJ, Kolb M, Galt T et al. Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function. J Am Soc Nephrol 2001; 12: 2029-2039
24. Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000; 182: 311-322
25. Woessner JF, Jr. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys 1961; 93: 440-447
26. Margetts PJ, Gyorffy S, KolbMet al. Antiangiogenic and antifibrotic gene therapy in a chronic infusion model of peritoneal dialysis in rats. J Am Soc Nephrol 2002; 13: 721-728
27. Ge G, Greenspan DS. BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein. J Cell Biol 2006; 175: 111-120
28. Annes JP, Munger JS, Rifkin DB. Making sense of latent TGF-beta activation. J Cell Sci 2003; 116: 217-224
29. Margetts PJ, Kolb M, Galt T et al. Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function. J Am Soc Nephrol 2001; 12: 2029-2039
30. Hetzel M, Bachem M, Anders D et al. Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts. Lung 2005; 183: 225-237
31. Yang L, Lin C, Zhao S et al. Phosphorylation of p68 RNA helicase plays a role in platelet-derived growth factor-induced cell proliferation by up-regulating cyclin D1 and c-Myc expression. J Biol Chem 2007; 282: 16811-16819