Synthesis and in vitro dual calcium channel antagonist-agonist activity of some 1, 4-Dihydo-2,6-dimethyl-3-nitro and cyano-4-(1-methyl-5-nitro-1H-imidazol- 2-yl)-5-pyridinecarboxylates

Daru

Volumn 16, Issue 4, 2008, Pages 263-270

  Miri, R ^a,b   Javidnia, K ^a,b   Mirkhani, H ^a   Kazemi, F ^b   Hemmateenejad, B ^b,c   Edraki, N ^a   Mehdipour, A R ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHIRAZ UNIVERSITY   (Iran)

Author keywords

Calcium channel antagonist agonist activity; Dihydropyridines; QSAR

Indexed keywords

1 METHYL 5 NITROIMIDAZOLE 2 CARBOXALDEHYDE; 1,4 DIHYDO 2,6 DIMETHYL 3 NITRO; 1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 3 AMINOCROTONITRYL; 4 [2 (DIFLUOROMETHOXY)PHENYL] 1,4,5,7 TETRAHYDRO 2 METHYL 5 OXOFURO[3,4 B]PYRIDINE 3 CARBOXYLIC ACID ETHYL ESTER; ACETIC ACID DERIVATIVE; ALDEHYDE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; CARBOXYLIC ACID DERIVATIVE; CYANO 4 (1 METHYL 5 NITRO IMIDAZOL 2 YL) 5 PYRIDINECARBOXYLATE DERIVATIVE; ISOPROPYL 3 AMINOCROTONATE; NIFEDIPINE; NITRILE; NITRO DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HEART LEFT ATRIUM; ILEUM; INOTROPISM; MALE; NONHUMAN; OUTCOME ASSESSMENT; STRUCTURE ACTIVITY RELATION;

EID: 58449093791     PISSN: 15608115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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