Lack of association between HLA-G 14 bp insertion/deletion polymorphism and response to longterm therapy with methotrexate response in rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 68, Issue 1, 2009, Pages 154-155

  Stamp, L K ^a,b   O'Donnell, J L ^a   Chapman, P T ^a   Barclay, M L ^a   Kennedy, M A ^b   Frampton, C M A ^b   Roberts, R L ^b  

^a CHRISTCHURCH HOSPITAL   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

HLA G ANTIGEN; METHOTREXATE; RHEUMATOID FACTOR;

ALLELE; DISEASE ACTIVITY; GASTROINTESTINAL SYMPTOM; GENE DELETION; GENE INSERTION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LETTER; NEUROLOGIC DISEASE; PRIORITY JOURNAL; QUESTIONNAIRE; RHEUMATOID ARTHRITIS; STATISTICAL ANALYSIS; TREATMENT RESPONSE;

ARTHRITIS, RHEUMATOID; CROSS-SECTIONAL STUDIES; FEMALE; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; METHOTREXATE; POLYMORPHISM, GENETIC; TREATMENT OUTCOME;

EID: 58349110722     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2008.089383     Document Type: Letter

References (4)

1. Kremer J. Methotrexate pharmacogenomics. Ann Rheum Dis 2006;55:1121-3.
2. Rizzo R. Rubini M, Govoni M, Padovan M, Melchiorri L, Stignani M, et al. HLA-G 14-bp polymorphism regulates the methotrexate response in rheumatoid arthritis. Pharmacogenet Genomics 2006; 16:615-23.
3. Baricordi O, Govoni M, Rizzo R, Trotta F. In rheumatoid arthritis, a polymorphism in the HLA-G gene concurs in the clinical response to methotrexate treatment. Ann Rheum Dis 2007; 66:1125-6.
4. Le Maoult J, Le Discorde M, Rouas-Freiss N, Moreau P, Menier C, McCluskey J, et al. Biology and functions of human leukocyte antigen-G in health and sickness. Tissue Antigens 2003; 62:273-84.