Analysis of breeding and pathology helps refine management practices of a large-scale N′-ethyl-N′-nitrosourea mouse mutagenesis programme

Laboratory Animals

Volumn 43, Issue 1, 2009, Pages 1-10

  Smith, A P L ^a   Polley, S ^a   Wells, S ^a   Stewart, M ^a   Vizor, L ^a   Humphreys, J ^a   Warren, M V ^b,c   Dear, N ^a,d   Cheeseman, M T ^a  

^a Medical Research Council Harwell Institute   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Breeding management; Mouse mutagenesis; N ethyl n nitrosourea; Pathology

Indexed keywords

MUTAGENIC AGENT; N' ETHYL N' MITROSOUREA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BREEDING; CANCER SURVIVAL; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; INFERTILITY; LUNG CARCINOMA; LYMPHOBLASTOMA; MALE; MORBIDITY; MORTALITY; MOUSE; MOUSE STRAIN; MUTAGENESIS; NONHUMAN;

AGE FACTORS; ANIMAL HUSBANDRY; ANIMAL WELFARE; ANIMALS; CASE-CONTROL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLNITROSOUREA; FEMALE; FERTILITY; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED STRAINS; MUTAGENESIS; MUTAGENS; NEOPLASMS, EXPERIMENTAL; RETROSPECTIVE STUDIES;

MUS;

EID: 58349089261     PISSN: 00236772     EISSN: None     Source Type: Journal    
DOI: 10.1258/la.2008.007072     Document Type: Article

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