Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness

Biochemical and Biophysical Research Communications

Volumn 379, Issue 2, 2009, Pages 304-308

  Tran, Truong An ^a,b   Gillet, Ludovic ^a,b   Roger, Sébastien ^a,b   Besson, Pierre ^a,b   White, Edward ^c   Le Guennec, Jean Yves ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Cancer invasiveness; MDA MB 231; MDA MB 468; Metastasis; NaV1.5; Taxol; Tubulin

Indexed keywords

MESSENGER RNA; PACLITAXEL; SODIUM CHANNEL; TETRODOTOXIN; TUBULIN; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN MDA MB 231; CELL STRAIN MDA MB 468; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS INHIBITION; MITOSIS INHIBITION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MITOSIS; NEOPLASM INVASIVENESS; PACLITAXEL; SIGNAL TRANSDUCTION; SODIUM CHANNELS; TUBULIN MODULATORS;

EID: 58249118000     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.12.073     Document Type: Article

References (15)

1. Dang G., and Hudis C. Adjuvant taxanes in the treatment of breast cancer: no longer at the tip of the iceberg. Clin. Breast Cancer 7 (2006) 51-58
2. Horwitz S. Taxol (Paclitaxel): mechanisms of action. Ann. Oncol. 5 (1994) S3-S6
3. Camacho J., Sanchez A., Stühmer W., and Pardo L. Cytoskeletal interactions determine the electrophysiological properties of human EAG potassium channels. Pflügers Arch. 441 (2000) 167-174
4. Roger S., Besson P., and Le Guennec J.-Y. Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line. Biochim. Biophys. Acta 1616 (2003) 107-111
5. Roger S., Rollin J., Barascu A., Besson P., Raynal P.-I., Iochmann S., Lei M., Bougnoux P., Gruel Y., and Le Guennec J.-Y. Voltage-gated sodium channels potentiate the invasive capacities of human non-small-cell lung cancer cell lines. Int. J. Biochem. Cell Biol. 39 (2007) 774-786
6. Roger S., Potier M., Vandier C., Besson P., and Le Guennec J.-Y. Voltage-gated sodium channels: new targets for epithelial cancer therapy?. Curr. Pharm. Des. 12 (2006) 3681-3695
7. Judé S., Roger S., Martel E., Besson P., Richard S., Bougnoux P., and Le Guennec J.-Y. Dietary long-chain omega-3 fatty acids of marine origin: a comparison of their protective effects on coronary heart disease and breast cancers. Prog. Biophys. Mol. Biol. 90 (2006) 299-325
8. Roger S., Besson P., and Le Guennec J.-Y. Influence of the whole cell patch-clamp configuration on electrophysiological properties of the voltage-dependent sodium current expressed in MDA-MB-231 breast cancer cells. Eur. Biophys. J. 33 (2004) 274-279
9. Maltsev V., and Undrovinas A. Cytoskeleton modulates coupling between availability and activation of cardiac sodium channel. Am. J. Physiol. 273 (1997) H1832-H1840
10. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
11. Tsutsui H., Ishihara K., and Cooper IV G. Cytoskeletal role in the contractile dysfunction of hypertrophied myocardium. Science 260 (1993) 682-687
12. 4 decoration of microtubules in adult cardiocytes. Am. J. Physiol. Heart Circ. Physiol. 285 (2003) H2072-H2083
13. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
14. Fraser S., Diss J., Chioni A., Mycielska M., Pan H., Yamaci R., Pani F., Siwy Z., Krasowska M., Grzywna Z., Brackenbury W., Theodorou D., Koyuturk M., Kaya H., Battaloglu E., De Bella M., Slade M., Tolhurst R., Palmieri C., Jiang J., Latchman D., Coombes R., and Djamgoz M. Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clin. Cancer Res. 11 (2005) 5381-5389
15. Motlagh D., Alden K., Russell B., and Garcia J. Sodium current modulation by a tubulin/GTP coupled process in rat neonatal cardiac myocytes. J. Physiol. 540.1 (2002) 93-103