The utility of routine laboratory testing in hypoglycaemic emergency department patients

Emergency Medicine Journal

Volumn 26, Issue 1, 2009, Pages 28-31

  Sinert, R ^a   Su, M ^a   Secko, M ^a   Zehtabchi, S ^a  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCOSE; INSULIN; ORAL ANTIDIABETIC AGENT; POTASSIUM; SODIUM; SULFONYLUREA;

ABNORMAL LABORATORY RESULT; ADULT; AGED; ARTICLE; COMBINATION CHEMOTHERAPY; DIABETES MELLITUS; ELECTROLYTE DISTURBANCE; EMERGENCY WARD; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPERKALEMIA; HYPOGLYCEMIA; HYPOKALEMIA; KIDNEY FAILURE; LABORATORY TEST; LEUKOCYTOSIS; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MONOTHERAPY; OUTCOME ASSESSMENT; PATIENT CARE; PHYSICAL EXAMINATION; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PYURIA; SODIUM BLOOD LEVEL; URINARY TRACT INFECTION;

ADULT; AGED; AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; DIAGNOSTIC TESTS, ROUTINE; EMERGENCIES; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; HYPOGLYCEMIA; MALE; MIDDLE AGED; PROGNOSIS; RISK FACTORS; YOUNG ADULT;

EID: 58249098591     PISSN: 14720205     EISSN: 14720213     Source Type: Journal    
DOI: 10.1136/emj.2008.060954     Document Type: Article

References (31)

1. Whipple AO. The surgical therapy of hyperinsulinism. J Int Chir 1938;3:237-76.
2. Mukherjee AK, Chowdhury MB. Metabolic emergencies in diabetes. J Indian Med Assoc 2006;104:244-6; 248.
3. Sloan FA, Bethel MA, Ruiz D Jr, et al. The growing burden of diabetes mellitus in the US elderly population. Arch Intern Med 2008;168:192-9; discussion 199.
4. National Institute of Diabetes and Digestive and Kidney Diseases. National diabetes Statistics fact sheet: general information and national estimates on diabetes in the United States, 2005. Bethesda, MD: US Department of Health and Human Services, National Institute of Health, 2005.
5. Johnson ES, Koepsell TD, Reiber G, et al. Increasing incidence of serious hypoglycemia in insulin users. J Clin Epidemiol 2002;55:253-9.
6. The DCCT Research Group. Epidemiology of severe hypoglycemia in the diabetes control and complications trial. Am J Med 1991; 90:450-9.
7. MacLeod KM, Hepburn DA, Frier BM. Frequency and morbidity of severe hypoglycaemia in insulin-treated diabetic patients. Diabet Med 1993;10:238-45.
8. Fisher BM, Heller SR. Mortality, cardiovascular morbidity and possible effects of hypoglycaemia on diabetic complications. In: Frier BM, Fisher BM, eds. Hypoglycaemia in clinical diabetes. Chichester: John Wiley and Sons, 1999;167-86.
9. Kagansky N, Levy S, Rimon E, et al. Hypoglycemia as a predictor of mortality in hospitalized elderly patients. Arch Intern Med 2003;163:1825-9.
10. Cryer PE, Davis SN, Shamoon H. Hypoglycemia in diabetes. Diabetes Care 2003;26:1902-12.
11. Lang CH, Dobrescu C. Sepsis-induced increases in glucose uptake by macrophage-rich tissues persist during hypoglycemia. Metabolism 1991;40:585-93.
12. Frizell M, Larsen PR. Field JB. Spontaneous hypoglycemia associated with chronic renal failure. Diabetes 1973; 22:493-8.
13. Felig P, Brown WV, Levine RA, et al. Glucose homeostasis in viral hepatitis. N Engl JMed 1970;283:1436-40.
14. Rabkin R, Ryan MP, Duckworth WC. The renal metabolism of insulin. Diabetologia 1984;27:351-7.
15. Duckworth WC. Insulin degradation: mechanisms, products, and significance. Endocr Rev 1988;9:319-45.
16. Krepinsky J, Ingram AJ, Close CM. Prolonged sulfonylurea-induced hypoglycemia in diabetic patients with end-stage renal disease. Am J Kidney Dis 2000;35:500-5.
17. Gan SC, Barr J, Arieff AI, et al. Biguanide-associated lactic acidosis. Case report and review of the literature. Arch Intern Med 1992;152:2333-6.
18. Biava C, Grossman A, West M. Ultrastructural observations on renal glycogen in normal and pathologic human kidneys. Lab Invest 1966;15:330-56.
19. Gerich JE. Glucose counterregulation and its impact on diabetes mellitus. Diabetes 1988;37:1608-17.
20. Cersosimo E, Molina PE, Abumrad N. Renal glucose production during insulin-induced hypoglycemia. Diabetes 1997;47:643-6.
21. Lang CH, Dobrescu C. Gram-negative infection increases noninsulin-mediated glucose disposal. Endocrinology 1991; 128:645-53.
22. Meszaros K, Lang CH, Bagby GJ, et al. Contribution of different organs to increased glucose consumption after endotoxin administration. J Biol Chem 1987;262:10965-70.
23. Shorr RI, Ray WA, Daugherty JR, et al. Incidence and risk factors for serious hypoglycemia in older persons using insulin or sulfonylureas. Arch Intern Med 1997;157:1681-6.
24. Donnelly LA, Morris AD, Frier BM, et al. Frequency and predictors of hypoglycaemia in type 1 and insulin-treated type 2 diabetes: a population-based study. Diabet Med 2005; 22:749-55.
25. Pramming S, Thorsteinsson B, Bendtson I, et al. Symptomatic hypoglycaemia in 411 type 1 diabetic patients. Diabet Med 1991; 8:217-22.
26. Akram K, Federsen-Bjergaard U, Carstensen B, et al. Frequency and risk factors of severe hypoglycaemia in insulin-treated type 2 diabetes: a cross-sectional survey. Diabet Med 2006; 23:750-6.
27. Leese GP, Wang J, Broomhall J, et al. Frequency of severe hypoglycemia requiring emergency treatment in type 1 and type 2 diabetes: a population-based study of health service resource use. Diabetes Care 2003;26:1176-80.
28. Frier BM, Fisher BM. Impaired hypoglycaemia awareness. In: Frier BM, Fisher BM, eds. Hypoglycaemia in clinical diabetes. Chichester, UK: John Wiley and Sons, 1999:111-46.
29. Cryer PE, Davis SN, Shamoon H. Hypoglycemia in diabetes. Diabetes Care 2003;26:1902-12.
30. Davis SN, Tate D. Effects of morning hypoglycemia on neuroendocrine and metabolic responses to subsequent afternoon hypoglycemia in normal man. J Clin Endocrinol Metab 2001; 86:2043-50.
31. Heller SR, Cryer PE. Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes 1991;40:223-6.