Real life evaluation of intravenous antibiotic treatment in a paediatric cystic fibrosis centre: Outcome of home therapy is not inferior

Respiratory Medicine

Volumn 103, Issue 2, 2009, Pages 244-250

  Proesmans, M ^a   Heyns, Lieve ^b   Moons, Philip ^b   Havermans, Trudy ^a   De Boeck, Kris ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Cystic fibrosis; Home therapy; Intravenous antibiotics; Lung infection; Outcome; Paediatric

Indexed keywords

ANTIBIOTIC AGENT; IMMUNOGLOBULIN G;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG EFFICACY; DRUG SAFETY; EVALUATION; FEMALE; FORCED EXPIRATORY VOLUME; HOME CARE; HOSPITAL CARE; HUMAN; LUNG INFECTION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PHYSIOTHERAPY; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; TREATMENT OUTCOME;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; CLINICAL PROTOCOLS; CYSTIC FIBROSIS; DRUG ADMINISTRATION ROUTES; FEMALE; HOME CARE SERVICES; HUMANS; INJECTIONS, INTRAVENOUS; MALE; QUALITY OF LIFE; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES;

EID: 58249084601     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2008.08.017     Document Type: Article

References (26)

1. Ratjen F., and Doring G. Cystic fibrosis. Lancet 361 (2003) 681-689
2. Orenstein D.M., Winnie G.B., and Altman H. Cystic fibrosis: a 2002 update. J Pediatr 140 (2002) 156-164
3. Frederiksen B., Lanng S., Koch C., and Hoiby N. Improved survival in the Danish center-treated cystic fibrosis patients: a result of aggressive treatment. Pediatr Pulmonol 21 (1996) 153-158
4. Doring G., Hoiby N., and the Consensus Study Group. Early intervention and prevention of lung disease in cystic fibrosis: a European consensus. J Cyst Fibros 3 (2004) 67-91
5. Elliot R.A., Webb A.K., and Tully M.P. Comparing costs of home-versus hospital-based treatment of infections in adults in a specialist cystic fibrosis center. Int J Technol Assess Health Care 21 (2005) 506-510
6. Strandvik B., Hjelte L., and Widen B. Home intravenous antibiotic treatment in cystic fibrosis. Scand J Gastroenterol Suppl. 143 (1988) 119-120
7. Gilbert J., Robinson T., and Littlewood J.M. Home intravenous antibiotic treatment in cystic fibrosis. Arch Dis Child 63 (1988) 512-517
8. Winter R.J., George R.J., Deacock S.J., Shee C.D., and Geddes D.M. Self-administered home intravenous antibiotic treatment in bronchiectasis and adult cystic fibrosis. Lancet 1 (1984) 1338-1339
9. Donati M.A., Guenette G., and Auerbach H. Prospective controlled study of home and hospital therapy of cystic fibrosis pulmonary disease. J Pediatr 111 (1987) 28-33
10. Pond M.N., Newport M., Joanes D., and Conway S.P. Home versus hospital intravenous antibiotic therapy in the treatment of young adults with cystic fibrosis. Eur Respir J 7 (1994) 1640-1644
11. Riethmueller J., Busch A., Damm V., Ziebach R., and Stern M. Home and hospital antibiotic treatment prove similar effective in cystic fibrosis. Infection 30 (2002) 387-391
12. Strandvik B., Hjelte L., Malmborg A.-S., and Widen B. Home intravenous antibiotic treatment of patients with cystic fibrosis. Acta Paediatr 81 (1992) 340-344
13. Thornton J., Elliot R., Tully M.P., Dodd M., and Webb A.K. Long term clinical outcome of home and hospital intravenous antibiotic treatment in adults with cystic fibrosis. Thorax 59 (2004) 242-246
14. Bradley J.M., Wallace E.S., Elborn J.S., Howard J.L., and Mc Coy M.P. An audit of the effect on intravenous antibiotic treatment on spirometric measures of pulmonary function in cystic fibrosis. Ir J Med Sci 168 (1999) 25-28
15. Bosworth D.G., and Nielson D.W. Effectiveness of home versus hospital care in the routine treatment of cystic fibrosis. Pediatr Pulmonol 24 (1997) 42-47
16. Thornton J., Elliott R.A., Tully M.P., Dodd M., and Webb A.K. Clinical and economic choices in the treatment of respiratory infections in cystic fibrosis: comparing hospital and home care. J Cyst Fibros 4 (2005) 239-247
17. Yi M.S., Tsevat J., Wilmott R.W., Kotagal U.R., and Britto M.T. The impact of treatment of pulmonary exacerbations on the health related quality of life of patients with cystic fibrosis: does hospitalization make a difference?. J Pediatr 144 (2004) 711-718
18. Van Aalderen W.M., Mannes G.P., Van Bommel G., Voorthuis I., Bosma E., and Heymans H.S. Continue intraveneuze thuisbehandeling met antibiotica van luchtweginfecties bij 11 patiënten met cystische fibrose in Noord-Nederland. Ned Tijdschr Geneeskd 137 (1993) 2482-2486
19. Nazer D., Abdulhamid I., Thomas R., and Pendleton S. Home versus hospital intravenous antibiotic therapy for acute pulmonary exacerbations in children with cystic fibrosis. Pediatr Pulmonol 41 (2006) 744-749
20. Knudson R.B., Lebowitz M.D., Holberg C.J., and Burrows B. Changes in maximal expiratory flow-volume curve with growth and aging. Am Rev Respir Dis 127 (1983) 725-734
21. American Thoracic Society. Standardization of spirometry. Am J Respir Crit Care Med 152 (1995) 1107-1136
22. Cole T.J., Freeman J.V., and Preece M.A. Body mass index reference curves for the UK, 1990. Arch Dis Child 73 (1995) 25-29
23. Doring G., Conway S.P., Heijerman H.G., Hodson M.E., Hoiby N., Smyth A., et al. Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus. Eur Respir J 16 (2000) 749-767
24. Rosenfeld M., Davis R., Fitzsimmons S., Pepe M., and Ramsey B. Gender gap in cystic fibrosis mortality. Am J Clin Epidemiol 145 (1997) 794-803
25. Wolter J.M., Bowler S.D., Nolan P.J., and McCormack J.G. Home intravenous therapy in cystic fibrosis: a prospective randomized trial examining clinical, quality of life and cost aspects. Eur Respir J 10 (1997) 896-900
26. Esmond G., Butler M., and Mc Cormack A.M. Comparison of hospital and home intravenous antibiotic therapy in adults with cystic fibrosis. J Clin Nurs 15 (2006) 52-60