Home intravenous therapy in cystic fibrosis: A prospective randomized trial examining clinical, quality of life and cost aspects

European Respiratory Journal

Volumn 10, Issue 4, 1997, Pages 896-900

  Wolter, J M ^a   Bowler, S D ^b   Nolan, P J ^b   McCormack, J G ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b NONE

Author keywords

Cost; Cystic fibrosis; Home therapy; Quality of life

Indexed keywords

ANTIBIOTIC AGENT;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; CYSTIC FIBROSIS; HEALTH CARE COST; HOME CARE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; PNEUMONIA; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; ANTI-BACTERIAL AGENTS; CEFTAZIDIME; COST-BENEFIT ANALYSIS; CYSTIC FIBROSIS; FEMALE; HOME INFUSION THERAPY; HOSPITALIZATION; HUMANS; MALE; PROSPECTIVE STUDIES; QUALITY OF LIFE; TOBRAMYCIN; TREATMENT OUTCOME;

EID: 0030935245     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Donati MA, Guenette G, Auerbaeh H. Prospective controlled study of home and hospital therapy of cystic fibrosis pulmonary disease. J Pediatr 1987; 111: 28-33.
2. Winter RJD, George RID, Deacock SJ, Shee CD, Geddes DM. Self-administered home intravenous antibiotic therapy in bronchiectasis and cystic fibrosis. Lancet 1984; 23 (3): 1338-1339.
3. Gilbert J, Robinson T, Littlewood JM. Home intravenous antibiotic treatment in cystic fibrosis. Arch Dis Child 1988; 63: 512-517.
4. Strandvik B, Hjelte L, Malmborg A-S, Widen B. Home intravenous antibiotic treatment of patients with cystic fibrosis. Acta Paediatr 1992; 81: 340-344.
5. van Aalderen WMC, Mannes GPM, Bosma ES, Roorda RJ, Heymans HSA. Home care in cystic fibrosis patients. Eur Respir J 1995; 8: 172-175.
6. Bakker W, Vinks AA, Mouton JW, De Jonge P, Verzijl JG, Heijerman HG. Continuous intravenous home treatment of airways infections using ceftazidime administration via portable pump in patients with cystic fibrosis; a multicenter study. Ned Tijsdchr Geneeskd 1993; 137: 2486-2491.
7. Pond MN, Newport M, Joanes D, Conway SP. Home versus hospital intravenous antibiotic therapy in the treatment of young adults with cystic fibrosis. Eur Respir J 1994; 7: 1640-1644.
8. Ramsey BW, Boat TF. Outcome measures for clinical trials in cystic fibrosis. J Paediatr 1994; 124: 177-192.
9. McGavin CR, Gupta SP, MeHardy GJR. Twelve minute walking test for assessing disability in chronic bronchitis. Br Med J 1976; 1: 82-83.
10. Guyatt GH, Berman LB, Townsend M, Pugsley SO, Chambers LW. A measure of QOL for clinical trials in chronic lung disease. Thorax 1987; 42: 773-778.
11. Nordstrom L, Ringberg H, Cronberg S, Tjernstrom O, Walder M. Does administration of an aminoglycoside in a single daily dose affect its efficacy and toxicity? J Antimicrob Chemother 1990; 25: 159-173.
12. Brummett RE, Morrison RB. The incidence of aminoglycoside antibiotic-induced hearing loss. Arch Otolaryngol Head Neck Surg 1990; 116: 406-409.
13. McCue JD. Out-patient i.v. antibiotic therapy: practical and ethical considerations. Hosp Pract 1988; 1 (8390): 208-211.
14. Fausti SA, Henry JA, Schaffer HI, Olson DJ, Frey RH, McDonald WJ. High-frequency audiometric monitoring for early detection of aminoglycoside toxicity. J Infect Dis 1992; 165: 1026-1043.
15. Poretz DM. Home intravenous antibiotic therapy. Geriatric Home Care 1991; 7: 749-763.
16. Balinsky W, Nesbitt S. Cost-effectiveness of out-patient parental antibiotics: a review of the literature. Am J Med 1989; 87: 301-305.
17. Graham DR, Keldermans MM, Klemm LW, Semenza NJ, Shafer ML. Infectious complications among patients receiving home intravenous therapy with peripheral, central, or peripherally placed central venous catheters. Am J Med 1991; 91(S3B): 3B-95S-3B100S.
18. Gravert C, Schulz E, Sack K. Ceftazidime in intensive care medicine and haemofiltration. J Antimicrob Chemother 1983; 12 (Suppl. A): 117-180.
19. Norrby SR, Finch RG, Glauser M, a European Study Group. Monotherapy in serious hospital-acquired infections: a clinical trial of ceftazidime versus imipenem/ cilastatin. J Antimicrob Chemother 1993; 31: 927-937.
20. Keresmar CM, Stem RC, Reed MD, Myers CM, Murdell D, Blumer JL. Ceftazidime in cystic fibrosis: pharmacokinetics and therapeutic response. J Antimicrob Chemother 1983; 12 (Suppl. A): 289-295.
21. Thickson ND. Economics of home intravenous services. Pharmacoeconomics 1993; 3: 220-227.