Abnormal proteins in primary breast cancer tissues from 25 Sudanese patients

European Journal of Inflammation

Volumn 6, Issue 3, 2008, Pages 115-121

  Ahamed, Mohammed Elimam ^a   Ahmed, M E ^a   Eltoum, A M ^a   Altahir, G O ^a   Ahmed, K M ^a   Harbi, S O ^a   Stanslas, J ^b   Mohamed, A O ^a  

^a UNIVERSITY OF KHARTOUM   (Sudan)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Chain A; Isoform2 of beta tropomyosin; rcTPM3; Thioredoxin mutant; X ray crystal structure of human galectin 1

Indexed keywords

AMINO ACID DERIVATIVE; ASPARAGINE; ASPARTIC ACID; BETA TROPOMYOSIN; CYSTEINE; GALECTIN 1; ISOPROTEIN; MUTANT PROTEIN; PROTEIN RCTPM3; PROTEIN SUBUNIT; THIOREDOXIN; TROPOMYOSIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN DETECTION; ARTICLE; BREAST CANCER; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG RESEARCH; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONTENT; PROTEIN DEFECT; PROTEIN DETERMINATION; PROTEIN STRUCTURE; PROTEIN TARGETING; SUDAN; TWO DIMENSIONAL GEL ELECTROPHORESIS; X RAY;

EID: 58149510590     PISSN: 1721727X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1721727X0800600303     Document Type: Article

References (33)

1. Amir H, Kwesigabo G, Aziz MR, Kitinya JN. Breast cancer and conservative surgery in sub-Saharan Africa. East Afr Med J 1996; 73(2):83-7.
2. Bray F, McCarron P, Parkin DM. The changing global patterns of female breast cancer incidence and mortality. Breast Cancer Res 2004; 6:229-39.
3. De Potter CR, Schelfhout AM, De Smet FH, Van Damme S, De Rider L, Dhont E, Van Emmelo J. A monoclonal antibody directed against a human cell membrane antigen prevents cell substrate adhesion and tumor invasion. Am J Pathol 1994; 144:95-103.
4. Rohrer JW, Barsoum AL, Dyess DL, Tucker JA, Coggin JH. Human breast carcinoma patients develop cloneable oncofetal antigen-specific effector and regulatory T lymophocytes. J Immunol 1999; 162:6880-92.
5. Disis ML, Goodell V, Sciffman K, Kunston KL. Humoral epitope spreading following immunization with a HER-2/neu peptide based vaccine. J Clin Immunol 2004 15; 24:571-8.
6. Berois N, Mazal D, Ubillos L, Trajtenberg F, Nicolas A, Sastre-Garau X, Magdelenat H, Osinaga E. UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyl-transferase-6 as a new immunohistochemical breast cancer marker. J Histochem Cytochem 2006; 54(3):317-28.
7. Somiari RI, Sullivan A, Russell S, et al. High-throughput proteomic analysis of human infiltrating ductal carcinoma of the breast. Proteomics 2003; 3: 1863-73.
8. Powis G, Montfort WR. Properties and biological activities of Thioredoxins. Ann Rev Pharmacol Toxicol 2001; 41:261-95.
9. Luthman M, Holgren A. Rat liver thioredoxin and thioredoxin reductase: purification and characterization. Biochemistry 1982; 21:6628-33.
10. Powis G, Oblong AE, Gasdaska PY, Berggren M, Hill S, Kirkpatrick DL. The thioredoxin/thioredoxin reductase redox system and control of cell growth. Oncol Res 1994; 6:539-44.
11. Andersen JF, Sanders DA, Gasdaska JR, Weichsel A, Powis G, Montfort WR. Human thioredoxin homodimers: regulating by pH, role of aspartate 60, and crystal structure of the spartate 60 → asparagine mutant. Biochemistry 1997; 36:13979-88.
12. Husbeck B, Powis G. The redox protein thioredoxin-1 regulates the constitutive and inducible expression of estrogen metabolizing cytochromes P450 1B1 and 1A1 in MCF-1 human breast cancer cells. Carcinogenesis 2002; 10:1625-30.
13. Gallegos A, Gasdaska JR, Taylor CW, et al. Transfection with human thioredoxin increases cell proliferation and a dominant - negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells. Cancer Res 1996; 56: 5765-70.
14. Wiest I, Seliger C, Walzel, H, Friese K, Jeschke U. Induction of apoptosis in human breast cancer and trophoblast tumor cells by galectin-1. Anticancer Res 2005; 25:1575-80.
15. Perillo NL, Marcus ME, Baum LG. Galectins: Versatile mediators of cell adhesion, cell proliferation, and cell death. J Mol Med 1998; 76: 402-12.
16. Harvey S, Zhang Y, Landry F, Miller C, Smith JW. Insights into a plasma membrane signature. Physiol Genomics 2001; 5:129-36.
17. Jung EG, Moon HG, Cho BI, et al. Galectin-1 expression in cancer-associated stromal cells correlates tumor invasiveness and tumor progression in breast cancer. Int J Cancer 2007: 120:2331-8.
18. André S, Kojima S, Yamazake N, Fink C, Kaltner H, Kayser K, Gabius HJ. Galectins-1 and -3 and their ligands in tumor biology. J Cancer Res Clin Oncol 1999; 125:461-74.
19. Weist I, Seliger C, Walzel H, Friese K, Jeschke U. Induction of apoptosis in human breast cancer and trophoblast tumor cells by galectin-1. Anticancer Res 2005; 25:1575-80.
20. Lopez-Lucendo MF, Solis D, Andre S, Hirabayashi J, Kasai K, Kaltner H, Gabius HJ, Romero A. Growth regulatory human galectin-1: crystallographic characterization of the structural changes induced by single site mutations and their impact on the thermodynamics of ligand binding. J Mol Biol 2004; 343:957-70.
21. Brosius J. Retroposons - seeds of evolution. Science 1991; 251:753-62.
22. Mighell AJ, Smith NR, Robinson PA, Markham AF. Vertebrate pseudo genes. FEBS Lett 2000; 468:109-14.
23. Marques AC, Dupanloup I, Vinckenbosch N, Reymond A, Kaessmman H. Emergence of young human genes after a burst of retroposition in primates. PloS Biology 2005; 357:1970-9.
24. Widada JS, Ferraz C, Capony JP, Liautard JP. Complete nucleotide sequence of the adult skeletal isoform of human skeletal muscle beta-tropomyosin. Nucleic Acids Res 1998; 16:3109.
25. Prasad GL, Meissner S, Sheer DG, Cooper HL. A cDNA encoding a muscle-type tropomyosin cloned from a human epithelial cell line: identity with human fibroblast tropomyosin. Biochem Biophys Res Commun 1981; 177:1068-75.
26. Libri D, Mouly V, Lemonnier M, Fiszman MY. A non muscle tropomyosin is encoded by the smooth/skeletal beta-tropomyosin gene and its RNA is transcribed from an internal promoter. J Bio Chem 1990; 265:3471-3.
27. Squire JM, Morris EP. A new look at thin filament regulation in vertebrate skeletal muscle. FASEB J 1998; 12:761-73.
28. Donner K, Ollikainen M, Ridanpaa M, Christen H, Wallgren-Pettersson C. Mutations in Beta - Tropomyosin (TPM2) gene - a rare cause of nemaline myopathy. Neuromusc Disord 2002; 12:151-8.
29. Bamshad M, Jorde LB, Carey JC. A revised and extended classification of the distal Arthrogryposes. Am J Genet 1996; 65:277-81.
30. Li DQ, Wang L, Fei F, et al. Identification of breast cancer metastasis associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trapmass spectrometry. Proteomic 2006; 11:3352-68.
31. Bahttacharya B, Prasad GL, Valverius EM, Salomon DS, Cooper HL. Tropomyosins of human mammary epithelial cells: consistent defects of expression in mammary carcinoma cell lines. Cancer Res 1990; 50(7):2105-12.
32. Raval GN, Bharadwaj S, Levine EA, Willingham MC, Geary RL, Kute T, Prasad GL. Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors. Oncogene 2003; 22:6194-203.
33. Ben-Yosef T, Francomano CA. Nucleotide sequence of the human TPM2 gene. EMBL GenBank DDBJ databases submitted Nov, 1999; P07951.