Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 51, 2008, Pages 20488-20493

  Kalamvoki, Maria ^a   Roizman, Bernard ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

DNA transfection; ND10 bodies; Silencing

Indexed keywords

BUTYRIC ACID; DNA; HISTONE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; ICP0 PROTEIN; ND10 PROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL STRAIN HEK293; DNA RESPONSIVE ELEMENT; DNA TRANSFECTION; DOSE RESPONSE; EMBRYO; GENE EXPRESSION; GENETIC TRANSFECTION; HEP 2 GENE; HERPES SIMPLEX VIRUS 1; HETEROCHROMATIN; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; RABBIT; SKIN CELL; U2OS GENE; VIRUS GENE; VIRUS INFECTION; WILD TYPE;

ACETYLATION; ANIMALS; BUTYRATES; CELL NUCLEUS; DNA; ENZYME INHIBITORS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HISTONE DEACETYLASES; HUMANS; IMMEDIATE-EARLY PROTEINS; PROTEIN TRANSPORT; RABBITS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; VIRAL PROTEINS;

HUMAN HERPESVIRUS 1; ORYCTOLAGUS CUNICULUS;

EID: 58149503667     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810879105     Document Type: Article

References (17)

1. Gelman IH, Silverstein S (1985) Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene. Proc Natl Acad Sci USA 82:5265-5269.
2. O'Hare P, Hayward GS (1985) Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters. J Virol 53:751-760.
3. Quinlan MP, Knipe DM (1985) Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions. Mol Cell Biol 5:957-963.
4. Eidson KM, Hobbs WE, Manning BJ, Carlson P, DeLuca NA (2002) Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection. J Virol 76:2180-2191.
5. Gu H, Roizman B (2007) Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex. Proc Natl Acad Sci USA 104:17134-17139.
6. Lin R, Noyce RS, Collins SE, Everett RD, Mossman KL (2004) The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7- mediated activation of interferon-stimulated genes. J Virol 78:1675-1684.
7. Melroe GT, DeLuca NA, Knipe DM (2004) Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J Virol 78:8411-8420.
8. Chee AV, Lopez P, Pandolfi PP, Roizman B (2003) Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effects. J Virol 77:7101-7105.
9. Hagglund R, Roizman B (2004) Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1. J Virol 78:2169-2178.
10. Lopez P, Van SC, Roizman B (2001) Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1. J Virol 75:3832-3840.
11. Van SC, Kawaguchi Y, Roizman B (1999) A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate. Proc Natl Acad Sci USA 96:8184-8189.
12. Ching RW, Dellaire G, Eskiw CH, Bazett-Jones DP (2005) PML bodies: A meeting place for genomic loci? J Cell Sci 118:847-854.
13. Tsukamoto T, et al. (2000) Visualization of gene activity in living cells. Nat Cell Biol 2:871-878.
14. Kalamvoki M, Qu J, Roizman B (2008) Translocation and colocalization of ICP4 and ICP0 in cells infected with herpes simplex virus 1 mutants lacking glycoprotein E, glycoprotein I, or the virion host shutoff product of the UL41 gene. J Virol 82:1701-1713.
15. Poon AP, Gu H, Roizman B (2006) ICP0 and the US3 protein kinase of herpes simplex virus 1 independently block histone deacetylation to enable gene expression. Proc Natl Acad Sci USA 103:9993-9998.
16. Zhong S, Salomoni P, Pandolfi PP (2000) The transcriptional role of PML and the nuclear body. Nat Cell Biol 2:E85-E90.
17. Gu H, Roizman B (2003) The degradation of promyelocytic leukemia and Sp100 proteins by herpes simplex virus 1 is mediated by the ubiquitin- conjugating enzyme UbcH5a. Proc Natl Acad Sci USA 100:8963-8968.