High-throughput evaluation of pulmonary surfactant adsorption and surface film formation

Journal of Lipid Research

Volumn 49, Issue 11, 2008, Pages 2479-2488

  Ravasio, Andrea ^a   Cruz, Antonio ^b   Pérez Gil, Jesús ^b   Haller, Thomas ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Air liquid interface; Fluorescence; Lamellar bodies; Lung; Microplate; Surface tension

Indexed keywords

ALBUMIN; LUNG SURFACTANT; PHOSPHOLIPID; PLASMA PROTEIN;

ADSORPTION KINETICS; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; BIOFILM; CONTROLLED STUDY; FLUORESCENCE; FLUORESCENCE MICROPLATE READER; HIGH THROUGHPUT SCREENING; INTERMETHOD COMPARISON; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS SURFACE TENSION; NONHUMAN; PHYSICAL PHASE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; REPRODUCIBILITY; SWINE; VALIDATION PROCESS; WILHELMY BALANCE MEASUREMENT; ADSORPTION; CHEMISTRY; LUMINESCENCE; LUNG; METHODOLOGY; SPECTROFLUOROMETRY; SURFACE TENSION;

ADSORPTION; LUMINESCENT MEASUREMENTS; LUNG; PHOSPHOLIPIDS; PULMONARY SURFACTANTS; SPECTROMETRY, FLUORESCENCE; SURFACE TENSION;

EID: 58149468454     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.D800029-JLR200     Document Type: Article

References (55)

1. Daniels, C. B., and S. Orgeig. 2003. Pulmonary surfactant: the key to the evolution of air breathing. News Physiol. Sci. 18: 151-157.
2. Perez-Gil, J. 2008. Structure of pulmonary surfactant membranes and films: the role of proteins and lipid-protein interactions. Biochim. Biophys. Acta. 1778: 1676-1695.
3. Hamvas, A., F. S. Cole, and L. M. Nogee. 2007. Genetic disorders of surfactant proteins. Neonatology. 91: 311-317.
4. Whitsett, J. A. 2006. Genetic disorders of surfactant homeostasis. Paediatr. Respir. Rev. 7 (Suppl.): 240-242.
5. Zimmermann, L. J., D. J. Janssen, D. Tibboel, A. Hamvas, and V. P. Carnielli. 2005. Surfactant metabolism in the neonate. Biol. Neonate. 87: 296-307.
6. deMello, D. E. 2004. Pulmonary pathology. Semin. Neonatol. 9: 311-329.
7. Taeusch, H. W., and K. M. Keough. 2001. Inactivation of pulmonary surfactant and the treatment of acute lung injuries. Pediatr. Pathol. Mol. Med. 20: 519-536.
8. Taeusch, H. W., J. B. de la Serna, J. Perez-Gil, C. Alonso, and J. A. Zasadzinski. 2005. Inactivation of pulmonary surfactant due to seruminhibited adsorption and reversal by hydrophilic polymers: experimental. Biophys. J. 89: 1769-1779.
9. Casals, C., A. Varela, M. L. Ruano, F. Valino, J. Perez-Gil, N. Torre, E. Jorge, F. Tendillo, and J. L. Castillo-Olivares. 1998. Increase of Creactive protein and decrease of surfactant protein A in surfactant after lung transplantation. Am. J. Respir. Crit. Care Med. 157: 43-49.
10. Bosma, K. J., and J. F. Lewis. 2007. Emerging therapies for treatment of acute lung injury and acute respiratory distress syndrome. Expert Opin. Emerg. Drugs. 12: 461-477.
11. Hammer, J. 2001. Acute lung injury: pathophysiology, assessment and current therapy. Paediatr. Respir. Rev. 2: 10-21.
12. Lacaze-Masmonteil, T. 2007. Expanded use of surfactant therapy in newborns. Clin. Perinatol. 34: 179-189.
13. Mazela, J., T. A. Merritt, J. Gadzinowski, and S. Sinha. 2006. Evolution of pulmonary surfactants for the treatment of neonatal respiratory distress syndrome and paediatric lung diseases. Acta Paediatr. 95: 1036-1048.
14. Blanco, O., and J. Perez-Gil. 2007. Biochemical and pharmacological differences between preparations of exogenous natural surfactant used to treat respiratory distress syndrome: role of the different components in an efficient pulmonary surfactant. Eur. J. Pharmacol. 568: 1-15.
15. Mingarro, I., D. Lukovic, M. Vilar, and J. Perez-Gil. 2008. Synthetic pulmonary surfactant preparations: new developments and future trends. Curr. Med. Chem. 15: 393-403.
16. Maruscak, A., and J. F. Lewis. 2006. Exogenous surfactant therapy for ARDS. Expert Opin. Investig. Drugs. 15: 47-58.
17. Gommers, D., J. J. Haitsma, and B. Lachmann. 2006. Surfactant as a carrier: influence of immunosuppressive agents on surfactant activity. Clin. Physiol. Funct. Imaging. 26: 357-361.
18. Haitsma, J. J., U. Lachmann, and B. Lachmann. 2001. Exogenous surfactant as a drug delivery agent. Adv. Drug Deliv. Rev. 47: 197-207.
19. Vermehren, C., S. Frokjaer, T. Aurstad, and J. Hansen. 2006. Lung surfactant as a drug delivery system. Int. J. Pharm. 307: 89-92.
20. Serrano, A. G., and J. Perez-Gil. 2006. Protein-lipid interactions and surface activity in the pulmonary surfactant system. Chem. Phys. Lipids. 141: 105-118.
21. Camacho, L., A. Cruz, R. Castro, C. Casals, and J. Perez-Gil. 1996. Effect of pH on the interfacial adsorption activity of pulmonary surfactant. Colloids Surf. B: Bioint. 5: 271-277.
22. Perez-Gil, J., J. Tucker, G. Simatos, and K. M. Keough. 1992. Interfacial adsorption of simple lipid mixtures combined with hydrophobic surfactant protein from pig lung. Biochem. Cell Biol. 70: 332-338.
23. Nag, K., J. Perez-Gil, M. L. Ruano, L. A. Worthman, J. Stewart, C. Casals, and K. M. Keough. 1998. Phase transitions in films of lung surfactant at the air-water interface. Biophys. J. 74: 2983-2995.
24. Enhorning, G. 2001. Pulmonary surfactant function studied with the pulsating bubble surfactometer (PBS) and the capillary surfactometer (CS). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 129: 221-226.
25. Seurynck, S. L., N. J. Brown, C. W. Wu, K. W. Germino, E. K. Kohlmeir, E. P. Ingenito, M. R. Glucksberg, A. E. Barron, and M. Johnson. 2005. Optical monitoring of bubble size and shape in a pulsating bubble surfactometer. J. Appl. Physiol. 99: 624-633.
26. Schurch, S., H. Bachofen, and F. Possmayer. 2001. Surface activity in situ, in vivo, and in the captive bubble surfactometer. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 129: 195-207.
27. Dobbs, L. G., R. Gonzalez, and M. C. Williams. 1986. An improved method for isolating type II cells in high yield and purity. Am. Rev. Respir. Dis. 134: 141-145.
28. Nanjee, M. N., A. K. Gebre, and N. E. Miller. 1991. Enzymatic fluorometric procedure for phospholipid quantification with an automated microtiter plate fluorometer. Clin. Chem. 37: 868-874.
29. Cruz, A., L. A. Worthman, A. G. Serrano, C. Casals, K. M. Keough, and J. Perez-Gil. 2000. Microstructure and dynamic surface properties of surfactant protein SP-B/dipalmitoylphosphatidylcholine interfacial films spread from lipid-protein bilayers. Eur. Biophys. J. 29: 204-213.
30. Haller, T., P. Dietl, H. Stockner, M. Frick, N. Mair, I. Tinhofer, A. Ritsch, G. Enhorning, and G. Putz. 2004. Tracing surfactant transformation from cellular release to insertion into an air-liquid interface. Am. J. Physiol. Lung Cell. Mol. Physiol. 286: L1009-L1015.
31. Bertocchi, C., A. Ravasio, S. Bernet, G. Putz, P. Dietl, and T. Haller. 2005. Optical measurement of surface tension in a miniaturized airliquid interface and its application in lung physiology. Biophys. J. 89: 1353-1361.
32. Schurch, S., F. H. Green, and H. Bachofen. 1998. Formation and structure of surface films: captive bubble surfactometry. Biochim. Biophys. Acta. 1408: 180-202.
33. Biswas, S. C., S. B. Rananavare, and S. B. Hall. 2007. Differential effects of lysophosphatidylcholine on the adsorption of phospholipids to an air/water interface. Biophys. J. 92: 493-501.
34. Schram, V., and S. B. Hall. 2001. Thermodynamic effects of the hydrophobic surfactant proteins on the early adsorption of pulmonary surfactant. Biophys. J. 81: 1536-1546.
35. Walters, R. W., R. R. Jenq, and S. B. Hall. 2000. Distinct steps in the adsorption of pulmonary surfactant to an air-liquid interface. Biophys. J. 78: 257-266.
36. Palmblad, M., M. Gustafsson, T. Curstedt, J. Johansson, and S. Schurch. 2001. Surface activity and film formation from the surface associated material of artificial surfactant preparations. Biochim. Biophys. Acta. 1510: 106-117.
37. Wustneck, R., J. Perez-Gil, N. Wustneck, A. Cruz, V. B. Fainerman, and U. Pison. 2005. Interfacial properties of pulmonary surfactant layers. Adv. Colloid Interface Sci. 117: 33-58.
38. Follows, D., F. Tiberg, R. K. Thomas, and M. Larsson. 2007. Multilayers at the surface of solutions of exogenous lung surfactant: direct observation by neutron reflection. Biochim. Biophys. Acta. 1768: 228-235.
39. Na Nakorn, P., M. C. Meyer, C. R. Flach, R. Mendelsohn, and H. J. Galla. 2007. Surfactant protein C and lung function: new insights into the role of alpha-helical length and palmitoylation. Eur. Biophys. J. 36: 477-489.
40. Nag, K., J. G. Munro, K. Inchley, S. Schurch, N. O. Petersen, and F. Possmayer. 1999. SP-B refining of pulmonary surfactant phospholipid films. Am. J. Physiol. 277: L1179-L1189.
41. Veldhuizen, E. J., R. V. Diemel, G. Putz, L. M. van Golde, J. J. Batenburg, and H. P. Haagsman. 2001. Effect of the hydrophobic surfactant proteins on the surface activity of spread films in the captive bubble surfactometer. Chem. Phys. Lipids. 110: 47-55.
42. Gustafsson, M., M. Palmblad, T. Curstedt, J. Johansson, and S. Schurch. 2000. Palmitoylation of a pulmonary surfactant protein C analogue affects the surface associated lipid reservoir and film stability. Biochim. Biophys. Acta. 1466: 169-178.
43. Inglese, J., R. L. Johnson, A. Simeonov, M. Xia, W. Zheng, C. P. Austin, and D. S. Auld. 2007. High-throughput screening assays for the identification of chemical probes. Nat. Chem. Biol. 3: 466-479.
44. Kumar, L., A. Amin, and A. K. Bansal. 2007. An overview of automated systems relevant in pharmaceutical salt screening. Drug Discov. Today. 12: 1046-1053.
45. Mishra, K. P., L. Ganju, M. Sairam, P. K. Banerjee, and R. C. Sawhney. 2008. A review of high throughput technology for the screening of natural products. Biomed. Pharmacother. 62: 94-98.
46. Gunasekara, L., W. M. Schoel, S. Schurch, and M. W. Amrein. 2008. A comparative study of mechanisms of surfactant inhibition. Biochim. Biophys. Acta. 1778: 433-444.
47. Gunther, A., C. Ruppert, R. Schmidt, P. Markart, F. Grimminger, D. Walmrath, and W. Seeger. 2001. Surfactant alteration and replacement in acute respiratory distress syndrome. Respir. Res. 2: 353-364.
48. Warriner, H. E., J. Ding, A. J. Waring, and J. A. Zasadzinski. 2002. A concentration-dependent mechanism by which serum albumin inactivates replacement lung surfactants. Biophys. J. 82: 835-842.
49. Kim, S. H., and E. I. Franses. 2006. Competitive adsorption of fibrinogen and dipalmitoylphosphatidylcholine at the air/aqueous interface. J. Colloid Interface Sci. 295: 84-92.
50. McEachren, T. M., and K. M. Keough. 1995. Phosphocholine reverses inhibition of pulmonary surfactant adsorption caused by Creactive protein. Am. J. Physiol. 269: L492-L497.
51. Touqui, L., and L. Arbibe. 1999. A role for phospholipase A2 in ARDS pathogenesis. Mol. Med. Today. 5: 244-249.
52. Schmidt, R., C. Ruppert, P. Markart, N. Lubke, L. Ermert, N. Weissmann, A. Breithecker, M. Ermert, W. Seeger, and A. Gunther. 2004. Changes in pulmonary surfactant function and composition in bleomycin-induced pneumonitis and fibrosis. Toxicol. Appl. Pharmacol. 195: 218-231.
53. Hite, R. D., M. C. Seeds, R. B. Jacinto, B. L. Grier, B. M. Waite, and D. A. Bass. 2005. Lysophospholipid and fatty acid inhibition of pulmonary surfactant: non-enzymatic models of phospholipase A2 surfactant hydrolysis. Biochim. Biophys. Acta. 1720: 14-21.
54. Gross, T., E. Zmora, Y. Levi-Kalisman, O. Regev, and A. Berman. 2006. Lung-surfactant-meconium interaction: in vitro study in bulk and at the air-solution interface. Langmuir. 22: 3243-3250.
55. Amato, M., S. Schurch, R. Grunder, H. Bachofen, and P. H. Burri. 1996. Influence of bilirubin on surface tension properties of lung surfactant. Arch. Dis. Child. Fetal Neonatal Ed. 75: F191-F196.