17β-Estradiol-induced remodeling of GABAergic axo-somatic synapses on estrogen receptor expressing neurons in the anteroventral periventricular nucleus of adult female rats

Neuroscience

Volumn 158, Issue 2, 2009, Pages 553-557

  Kurunczi, A ^a   Hoyk, Z ^a   Csakvari, E ^a   Gyenes, A ^a   Parducz A ^a  

^a INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

estrogen receptor; GABAergic; hormone; stereology; synaptic plasticity

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; 4 AMINOBUTYRIC ACID; ESTROGEN; ESTROGEN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CONTROLLED STUDY; FEMALE; GABAERGIC SYSTEM; HORMONAL REGULATION; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMUNOCYTOCHEMISTRY; NERVE CELL PLASTICITY; NEUROENDOCRINOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEREOLOGY; SYNAPTOGENESIS; ANIMAL; ANTERIOR HYPOTHALAMUS; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOELECTRON MICROSCOPY; METABOLISM; METHODOLOGY; NERVE CELL; NERVE FIBER; OVARIECTOMY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SYNAPSE;

ANIMALS; ANTERIOR HYPOTHALAMIC NUCLEUS; AXONS; ESTRADIOL; ESTROGENS; FEMALE; GAMMA-AMINOBUTYRIC ACID; MICROSCOPY, IMMUNOELECTRON; NEURONAL PLASTICITY; NEURONS; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; SYNAPSES;

EID: 58149465010     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.10.028     Document Type: Article

References (30)

1. Csakvari E., Hoyk Z., Gyenes A., Garcia-Ovejero D., Garcia-Segura L.M., and Parducz A. Fluctuation of synapse density in the arcuate nucleus during the estrous cycle. Neuroscience 144 (2007) 1288-1292
2. Csakvari E., Kurunczi A., Hoyk Z., Gyenes A., Naftolin F., and Parducz A. Estradiol-induced synaptic remodeling of tyrosine hydroxylase immunopositive neurons in the rat arcuate nucleus. Endocrinology 149 (2008) 4137-4141
3. Garcia-Segura L.M., Baetens D., and Naftolin F. Sex differences and maturational changes in arcuate nucleus neuronal plasma membrane organization. Brain Res 351 (1985) 146-149
4. Greenough W.T., Carter C.S., Steerman C., and DeVoogd T.J. Sex differences in dendritic patterns in hamster preoptic area. Brain Res 126 (1977) 63-72
5. Gu G.B., and Simerly R.B. Projections of the sexually dimorphic anteroventral periventricular nucleus in the female rat. J Comp Neurol 384 (1997) 142-164
6. Horvath T.L., Naftolin F., and Leranth C. Luteinizing hormone-releasing hormone and gamma-aminobutyric acid neurons in the medial preoptic area are synaptic targets of dopamine axons originating in anterior periventricular areas. J Neuroendocrinol 5 (1993) 71-79
7. Hutton L.A., Gu G., and Simerly R.B. Development of a sexually dimorphic projection from the bed nuclei of the stria terminalis to the anteroventral periventricular nucleus in the rat. J Neurosci 18 (1998) 3003-3013
8. Jung H., Shannon E.M., Fritschy J.M., and Ojeda S.R. Several GABAA receptor subunits are expressed in LHRH neurons of juvenile female rats. Brain Res 780 (1998) 218-229
9. Langub Jr. M.C., Maley B.E., and Watson Jr. R.E. Estrous cycle-associated axosomatic synaptic plasticity upon estrogen receptive neurons in the rat preoptic area. Brain Res 641 (1994) 303-310
10. Leranth C., Maclusky N.J., Sakamoto H., Shanabrough M., and Naftolin F. Glutamic acid decarboxylase-containing axons synapse on LHRH neurons in the rat medial preoptic area. Neuroendocrinology 40 (1985) 536-539
11. Matsumoto A., and Arai Y. Sexual dimorphism in 'wiring pattern' in the hypothalamic arcuate nucleus and its modification by neonatal hormonal environment. Brain Res 190 (1980) 238-242
12. Matsumoto A., and Arai Y. Effect of androgen on sexual differentiation of synaptic organization in the hypothalamic arcuate nucleus: an ontogenetic study. Neuroendocrinology 33 (1981) 166-169
13. Matsumoto A., and Arai Y. Neuronal plasticity in the deafferented hypothalamic arcuate nucleus of adult female rats and its enhancement by treatment with estrogen. J Comp Neurol 197 (1981) 197-205
14. Mitsushima D., Tin-Tin W.S., and Kimura F. Sexual dimorphism in the GABAergic control of gonadotropin release in intact rats. Neurosci Res 46 (2003) 399-405
15. Norgren Jr. R.B., and Lehman M.N. A double-label pre-embedding immunoperoxidase technique for electron microscopy using diaminobenzidine and tetramethylbenzidine as markers. J Histochem Cytochem 37 (1989) 1283-1289
16. Olmos G., Naftolin F., Perez J., Tranque P.A., and Garcia-Segura L.M. Synaptic remodeling in the rat arcuate nucleus during the estrous cycle. Neuroscience 32 (1989) 663-667
17. Orikasa C., Kondo Y., Hayashi S., McEwen B.S., and Sakuma Y. Sexually dimorphic expression of estrogen receptor beta in the anteroventral periventricular nucleus of the rat preoptic area: implication in luteinizing hormone surge. Proc Natl Acad Sci U S A 99 (2002) 3306-3311
18. Orikasa C., and Sakuma Y. Possible involvement of preoptic estrogen receptor beta positive cells in luteinizing hormone surge in the rat. Domest Anim Endocrinol 25 (2003) 83-92
19. Parducz A., Hoyk Z., Kis Z., and Garcia-Segura L.M. Hormonal enhancement of neuronal firing is linked to structural remodelling of excitatory and inhibitory synapses. Eur J Neurosci 16 (2002) 665-670
20. Parducz A., Perez J., and Garcia-Segura L.M. Estradiol induces plasticity of gabaergic synapses in the hypothalamus. Neuroscience 53 (1993) 395-401
21. Parducz A., Zsarnovszky A., Naftolin F., and Horvath T.L. Estradiol affects axo-somatic contacts of neuroendocrine cells in the arcuate nucleus of adult rats. Neuroscience 117 (2003) 791-794
22. Perez J., Naftolin F., and Garcia Segura L.M. Sexual differentiation of synaptic connectivity and neuronal plasma membrane in the arcuate nucleus of the rat hypothalamus. Brain Res 527 (1990) 116-122
23. Polston E.K., Gu G., and Simerly R.B. Neurons in the principal nucleus of the bed nuclei of the stria terminalis provide a sexually dimorphic GABAergic input to the anteroventral periventricular nucleus of the hypothalamus. Neuroscience 123 (2004) 793-803
24. Polston E.K., and Simerly R.B. Ontogeny of the projections from the anteroventral periventricular nucleus of the hypothalamus in the female rat. J Comp Neurol 495 (2006) 122-132
25. Raisman G., and Field P.M. Sexual dimorphism in the neuropil of the preoptic area of the rat and its dependence on neonatal androgen. Brain Res 54 (1973) 1-29
26. Sim J.A., Skynner M.J., Pape J.R., and Herbison A.E. Late postnatal reorganization of GABA(A) receptor signalling in native GnRH neurons. Eur J Neurosci 12 (2000) 3497-3504
27. Simerly R.B. Organization and regulation of sexually dimorphic neuroendocrine pathways. Behav Brain Res 92 (1998) 195-203
28. Somogyi P., and Hodgson A.J. Antisera to gamma-aminobutyric acid. III. Demonstration of GABA in Golgi-impregnated neurons and in conventional electron microscopic sections of cat striate cortex. J Histochem Cytochem 33 (1985) 249-257
29. Sterio D.C. The unbiased estimation of number and sizes of arbitrary particles using the disector. J Microsc 134 Pt 2 (1984) 127-136
30. Witkin J.W., Ferin M., Popilskis S.J., and Silverman A.J. Effects of gonadal steroids on the ultrastructure of GnRH neurons in the rhesus monkey: synaptic input and glial apposition. Endocrinology 129 (1991) 1083-1092