Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample

Neuropsychopharmacology

Volumn 34, Issue 3, 2009, Pages 698-706

  Hoft, Nicole R ^a   Corley, Robin P ^a   McQueen, Matthew B ^a   Schlaepfer, Isabel R ^a   Huizinga, David ^a   Ehringer, Marissa A ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Genetic association; Nicotine dependence; Nicotinic receptors; SNP; Tobacco use

Indexed keywords

ARTICLE; CHRNA6 GENE; CHRNB3 GENE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING CESSATION; TOBACCO DEPENDENCE;

ADOLESCENT; ADULT; CHILD; CONTINENTAL POPULATION GROUPS; DATA COLLECTION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LONGITUDINAL STUDIES; MALE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, NICOTINIC; SIBLINGS; SMOKING CESSATION; TOBACCO USE DISORDER; UNITED STATES;

EID: 58149463197     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2008.122     Document Type: Article

References (30)

1. Anchordoquy HC, McGeary C, Liu L, Krauter KS, Smolen A (2003). Genotyping of three candidate genes after whole-genome preamplification of DNA collected from buccal cells. Behav Genet 33: 73-78.
2. Barrett JC, Fry B, Maller J, Daly MJ (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
3. Bierut LJ, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau OF et al (2007). Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet 16: 24-35.
4. Brant-Zawadzki PB, Schmid DI, Jiang H, Weyrich AS, Zimmerman GA, Kraiss LW (2007). Translational control in endothelial cells. J Vasc Surg 45(Suppl A): A8-A14.
5. Champtiaux N, Gotti C, Cordero-Erausquin M, David DJ, Przybylski C, Lena C et al (2003). Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J Neurosci 23: 7820-7829.
6. Cottler LB, Keating SK (1990). Operationalization of alcohol and drug dependence criteria by means of a structured interview. Recent Dev Alcohol 8: 69-83.
7. Crabbe JC, Phillips TJ, Harris RA, Arends MA, Koob GF (2006). Alcohol-related genes: contributions from studies with genetically engineered mice. Addict Biol 11: 195-269.
8. Cui C, Booker TK, Allen RS, Grady SR, Whiteaker P, Marks MJ et al (2003). The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors. J Neurosci 23: 11045-11053.
9. Elliott DS, Huizinga D, Menard SW (1989). Multiple Problem Youth: Delinquency, Substance Use, and Mental Health Problems. Springer-Verlag: New York.
10. Fulker DW, Cherny SS, Sham PC, Hewitt JK (1999). Combined linkage and association sib-pair analysis for quantitative traits. Am J Hum Genet 64: 259-267.
11. Gotti C, Riganti L, Vailati S, Clementi F (2006a). Brain neuronal nicotinic receptors as new targets for drug discovery. Curr Pharm Des 12: 407-428.
12. Gotti C, Zoli M, Clementi F (2006b). Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends Pharmacol Sci 27: 482-491.
13. Greenbaum L, Kanyas K, Karni O, Merbl Y, Olender T, Horowitz A et al (2006). Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes. Mol Psychiatry 11: 312-322, 223.
14. Haberstick BC, Smolen A (2004). Genotyping of three single nucleotide polymorphisms following whole genome preamplification of DNA collected from buccal cells. Behav Genet 34: 541-547.
15. Hymowitz N, Cummings KM, Hyland A, Lynn WR, Pechacek TF, Hartwell TD (1997). Predictors of smoking cessation in a cohort of adult smokers followed for five years. Tob Control 6(Suppl 2): S57-S62.
16. Jarvis MJ (2004). Why people smoke. BMJ 328: 277-279.
17. Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM (2004). PBAT: tools for family-based association studies. Am J Hum Genet 74: 367-369.
18. Li MD, Cheng R, Ma JZ, Swan GE (2003). A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction 98: 23-31.
19. Maes HH, Sullivan PF, Bulik CM, Neale MC, Prescott CA, Eaves LJ et al (2004). A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependence. Psychol Med 34: 1251-1261.
20. Maziere P, Enright AJ (2007). Prediction of microRNA targets. Drug Discov Today 12: 452-458.
21. Mineur YS, Picciotto MR (2008). Genetics of nicotinic acetylcholine receptors: relevance to nicotine addiction. Biochem Pharmacol 75: 323-333.
22. Rebhan M, Chalifa-Caspi V, Prilusky J, Lancet D (1998). GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support. Bioinformatics 14: 656-664.
23. Rhee SH, Hewitt JK, Young SE, Corley RP, Crowley TJ, Stallings MC (2003). Genetic and environmental influences on substance initiation, use, and problem use in adolescents. Arch Gen Psychiatry 60: 1256-1264.
24. Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA et al (2007). Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet 16: 36-49.
25. Salminen O, Murphy KL, McIntosh JM, Drago J, Marks MJ, Collins AC et al (2004). Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Mol Pharmacol 65: 1526-1535.
26. Swan GE, Carmelli D, Rosenman RH, Fabsitz RR, Christian JC (1990). Smoking and alcohol consumption in adult male twins: genetic heritability and shared environmental influences. J Subst Abuse 2: 39-50.
27. The International HapMap Consortium (2003). The International HapMap Project. Nature 426: 789-796.
28. US Department of Health and Human Services. Reducing Tobacco Use: A Report of the Surgeon General. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2000.
29. Zeiger JS, Haberstick BC, Schlaepfer I, Collins AC, Corley RP, Crowley TJ et al (2008). The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco. Hum Mol Genet 17: 724-734.
30. Zhang L, Cui X, Schmitt K, Hubert R, Navidi W, Arnheim N (1992). Whole genome amplification from a single cell: implications for genetic analysis. Proc Natl Acad Sci USA 89: 5847-5851.