Role of endogenous bone marrow cells in long-term repair mechanisms after myocardial infarction

Journal of Cellular and Molecular Medicine

Volumn 12, Issue 6B, 2008, Pages 2867-2874

  Odörfer, Kathrin I ^a   Walter, Ingrid ^a   Kleiter, Miriam ^a   Sandgren, Eric P ^b   Erben, Reinhold G ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Bone marrow cells; Human placental alkaline phosphatase; Myocardial infarction; Regeneration; Stem cells; Tissue repair

Indexed keywords

ACTIN; ALKALINE PHOSPHATASE; CD68 ANTIGEN, HUMAN; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; PARAFFIN; VIMENTIN;

ANIMAL; ARTICLE; BONE MARROW CELL; CELL COUNT; ENZYMOLOGY; HEART INFARCTION; HEART MUSCLE; METABOLISM; PATHOLOGY; RAT; TIME; TRANSGENIC RAT; WOUND HEALING;

ACTINS; ALKALINE PHOSPHATASE; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BONE MARROW CELLS; CELL COUNT; MYOCARDIAL INFARCTION; MYOCARDIUM; PARAFFIN EMBEDDING; RATS; RATS, TRANSGENIC; TIME FACTORS; VIMENTIN; WOUND HEALING;

ANIMALIA; RATTUS;

EID: 58149456885     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00511.x     Document Type: Article

References (20)

1. Quaini F, Urbanek K, Beltrami AP, Finato N, Beltrami CA, Nadal-Ginard B, Kajstura J, Leri A, Anversa P. Chimerism of the transplanted heart. N Engl J Med. 2002 346 : 5 15.
2. Glaser R, Lu MM, Narula N, Epstein JA. Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts. Circulation. 2002 106 : 17 9.
3. Muller P, Pfeiffer P, Koglin J, Schafers HJ, Seeland U, Janzen I, Urbschat S, Bohm M. Cardiomyocytes of noncardiac origin in myocardial biopsies of human transplanted hearts. Circulation. 2002 106 : 31 5.
4. Deb A, Wang S, Skelding KA, Miller D, Simper D, Caplice NM. Bone marrow-derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients. Circulation. 2003 107 : 1247 9.
5. Ausoni S, Zaglia T, Dedja A, Di Lisi R, Seveso M, Ancona E, Thiene G, Cozzi E, Schiaffino S. Host-derived circulating cells do not significantly contribute to cardiac regeneration in heterotopic rat heart transplants. Cardiovasc Res. 2005 68 : 394 404.
6. Makino S, Fukuda K, Miyoshi S, Konishi F, Kodama H, Pan J, Sano M, Takahashi T, Hori S, Abe H, Hata J, Umezawa A, Ogawa S. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest. 1999 103 : 697 705.
7. Kucia M, Dawn B, Hunt G, Guo Y, Wysoczynski M, Majka M, Ratajczak J, Rezzoug F, Ildstad ST, Bolli R, Ratajczak MZ. Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction. Circ Res. 2004 95 : 1191 9.
8. Takahashi M, Hakamata Y, Murakami T, Takeda S, Kaneko T, Takeuchi K, Takahashi R, Ueda M, Kobayashi E. Establishment of lacZ-transgenic rats: a tool for regenerative research in myocardi-um. Biochem Biophys Res Commun. 2003 305 : 904 8.
9. Fukuhara S, Tomita S, Nakatani T, Ohtsu Y, Ishida M, Yutani C, Kitamura S. G-CSF promotes bone marrow cells to migrate into infarcted mice heart, and differentiate into cardiomyocytes. Cell Transplant. 2004 13 : 741 8.
10. Kuramochi Y, Fukazawa R, Migita M, Hayakawa J, Hayashida M, Uchikoba Y, Fukumi D, Shimada T, Ogawa S. Cardiomyocyte regeneration from circulating bone marrow cells in mice. Pediatr Res. 2003 54 : 319 25.
11. Möllmann H, Nef HM, Kostin S, von Kalle C, Pilz I, Weber M, Schaper J, Hamm CW, Elsasser A. Bone marrow-derived cells contribute to infarct remodelling. Cardiovasc Res. 2006 71 : 661 71.
12. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA. 2001 98 : 10344 9.
13. Zagzag D, Miller DC, Chiriboga L, Yee H, Newcomb EW. Green fluorescent protein immunohistochemistry as a novel experimental tool for the detection of glioma cell invasion in vivo. Brain Pathol. 2003 13 : 34 7.
14. Kisseberth WC, Brettingen NT, Lohse JK, Sandgren EP. Ubiquitous expression of marker transgenes in mice and rats. Dev Biol. 1999 214 : 128 38.
15. Odörfer KI, Unger NJ, Weber K, Sandgren EP, Erben RG. Marker tolerant, immuno-competent animals as a new tool for regenerative medicine and long-term cell tracking. BMC Biotechnol. 2007 7 : 30.
16. Antonitsis P, Ioannidou-Papagiannaki E, Kaidoglou A, Papakonstantinou C. In vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells. The role of 5-azacytidine. Interact Cardiovasc Thorac Surg. 2007 6 : 593 7.
17. Babai F, Musevi-Aghdam J, Schurch W, Royal A, Gabbiani G. Coexpression of alpha-sarcomeric actin, alpha-smooth muscle actin and desmin during myogenesis in rat and mouse embryos I. Skeletal muscle. Differentiation. 1990 44 : 132 42.
18. Yano T, Miura T, Ikeda Y, Matsuda E, Saito K, Miki T, Kobayashi H, Nishino Y, Ohtani S, Shimamoto K. Intracardiac fibroblasts, but not bone marrow derived cells, are the origin of myofibroblasts in myocardial infarct repair. Cardiovasc Pathol. 2005 14 : 241 6.
19. Virag JI, Murry CE. Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol. 2003 163 : 2433 40.
20. Nygren JM, Jovinge S, Breitbach M, Sawen P, Roll W, Hescheler J, Taneera J, Fleischmann BK, Jacobsen SE. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med. 2004 10 : 494 501.