The human H5N1 influenza A virus polymerase complex is active in vitro over a broad range of temperatures, in contrast to the WSN complex, and this property can be attributed to the PB2 subunit

Journal of General Virology

Volumn 89, Issue 12, 2008, Pages 2923-2932

  Bradel Tretheway, Birgit G ^a   Kelley, Z ^a   Chakraborty Sett, Shikha ^a   Takimoto, Toru ^a   Kim, Baek ^a   Dewhurst, Stephen ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; LYSINE; RNA POLYMERASE; MULTIENZYME COMPLEX; PB2 PROTEIN, INFLUENZAVIRUS A; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS; ARTICLE; CHIMERA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STABILITY; GENE EXPRESSION SYSTEM; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; VIRUS STRAIN; ANIMAL; CELL LINE; CYTOLOGY; ENDOTHELIUM CELL; ENZYMOLOGY; ISOLATION AND PURIFICATION; KIDNEY; LUNG; METABOLISM; MOUSE; TEMPERATURE;

AVES; INFLUENZA A VIRUS;

ANIMALS; CELL LINE; ENDOTHELIAL CELLS; ENZYME STABILITY; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; KIDNEY; LUNG; MICE; MULTIENZYME COMPLEXES; RNA REPLICASE; TEMPERATURE; VIRAL PROTEINS;

EID: 58149388469     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.2008/006254-0     Document Type: Article

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