Blunted response to hypercapnia: Synonymous with depressed respiratory drive?

Respiratory Care

Volumn 53, Issue 8, 2008, Pages 1006-1007

  Sassoon, Catherine S ^a  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE RESPIRATORY FAILURE; AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; ARTIFICIAL VENTILATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; DIAPHRAGM; DIAPHRAGM MUSCLE; EDITORIAL; ENDOTRACHEAL TUBE; ESOPHAGUS PRESSURE; HUMAN; HYPERCAPNIA; INTENSIVE CARE UNIT; LUNG VOLUME; MOUTH CAVITY; NEUROMUSCULAR DISEASE; POSITIVE END EXPIRATORY PRESSURE; PRESSURE SUPPORT VENTILATION; RESPIRATION CONTROL; RESPIRATORY DRIVE; RESPIRATORY SYSTEM; HOMEOSTASIS; LUNG FUNCTION TEST; METHODOLOGY; NOTE; PATHOPHYSIOLOGY; PHYSIOLOGY; PREDICTION AND FORECASTING; RESPIRATORY FAILURE;

HOMEOSTASIS; HUMANS; HYPERCAPNIA; PREDICTIVE VALUE OF TESTS; RESPIRATORY FUNCTION TESTS; RESPIRATORY INSUFFICIENCY; VENTILATOR WEANING;

EID: 58149388167     PISSN: 00201324     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (12)

1. Jubran A, Tobin MJ. Pathophysiologic basis of acute respiratory distress in patients who fail a trial of weaning from mechanical ventilation. Am J Respir Crit Care Med 1997;155(3):906-915. (Pubitemid 27133402)
2. Pourriat JL, Baud M, Lamberto C, Fosse JP, Cupa M. Effects of doxapram on hypercapnic response during weaning from mechanical ventilation in COPD patients. Chest 1992;10(6):1639-1643.
3. Whitelaw WA, Derenne JP. Airway occlusion pressure. J Appl Physiol 1993;74(4):1475-1483. (Pubitemid 23133431)
4. Kuhlen R, Hausmann S, Pappert D, Slama K, Rossaint R, Falke K. A new method for P0.1 measurement using standard respiratory equipment. Intensive Care Med 1995;21(7):554-560.
5. Read DJ. A clinical method for assessing the ventilatory response to carbon dioxide. Aust Ann Med 1967;16(1):20-32.
6. Irsigler GB. Carbon dioxide response line in young adults: the limits of the normal response. Am Rev Respir Dis 1976;114(3):529-536.
7. 2 under methoxyflurane anesthesia. J Appl Physiol 1976;40(5):805-814.
8. 2 response and hypercapnia in severe chronic obstructive pulmonary disease. Eur Respir J 1998;12(3):666-671.
9. Raurich JM, Rialp G, Ibáñez J, Campillo C, Ayestarán I, Blanco C. Hypercapnia test as a predictor of success in spontaneous breathing trials and extubation. Respir Care 2008;53(8):1012-1018.
10. Ranieri VM, Giuliani R, Mascia L, Grasso S, Petruzzelli V, Puntillo N, et al. Patient-ventilator interaction during acute hypercapnia: pressure-support vs. proportional-assist ventilation. J Appl Physiol 1996;81(1):426-436. (Pubitemid 26255540)
11. Laghi F, Cattapan SE, Jubran A, Parthasarathy S, Warshawsky P, Choi YS, Tobin MJ. Is weaning failure caused by low-frequency fatigue of the diaphragm? Am J Respir Crit Care Med 2003;167(2):120-127.
12. Montgomery AB, Holle RHO, Neagle SR, Pierson DJ, Schone RB. Prediction of successful ventilator weaning using airway occlusion pressure and hypercapnic challenge. Chest 1987;91(4):497-499. (Pubitemid 17058869)