The uses of radiotracers in the life sciences

Reports on Progress in Physics

Volumn 72, Issue 1, 2009, Pages

  Ruth, Thomas J ^a  

^a TRIUMF   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 58149376033     PISSN: 00344885     EISSN: None     Source Type: Journal    
DOI: 10.1088/0034-4885/72/1/016701     Document Type: Article

References (111)

1. Adelstein J S and Manning F J (ed) 1995 Isotopes for Medicine and the Life Sciences (Washington, DC: IOM, NAS Press)
2. Bingham I J, Glass A D M, Kronzucker H J, Robinson D and Scrimgeour C M 2000 Isotope techniques Root Methods: A Handbook ed A L Smit et al (Berlin: Springer) pp 365-402
3. Britto D T, Ruth T J, Lapi S and Kronzucker H J 2004 Cellular and whole-plant chloride dynamics in barley: insights into chloride-nitrogen interactions and salinity responses Planta 218 615-22
4. Campbell B 1995 Drug development and positron emission tomography PET for Drug Development and Evaluation ed D Comar (Dordrecht: Kluwer)
5. Catana C, Wu Y, Judenhofer M S, Qi J, Pichler B J and Cherry S R 2006 Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner J. Nucl. Med. 47 1968-76
6. Eckelman W C and Gibson R E 1993 The design of site-directed radiopharmaceuticals for use in drug discovery Nuclear Imaging in Drug Discovery, Development and Approval ed H D Burns et al (Boston: Birkhäuser) pp 113-34
7. Glass A D M, Britto D J, Kaiser B N, Kronzucker H J, Kumar A, Okamoto M, Siddiqi M Y and Vidmar J J 2002 The regulation of nitrate and ammonium transport systems in plants J. Exp. Bot. 53 855-64
8. Harbert J and da Roche A F G 1984 Textbook of Nuclear Medicine, Volume I: Basic Science 2nd edn (Philadelphia: Lea and Febiger)
9. Health Canada 2005 Bexxar available from: http://www.hc-sc.gc.ca/dhp-mps/ prodpharma/activit/proj/sbd-smd/nd-ad-2005-bexxar-084518-e.html. Accessed January 15th 2007
10. Health Canada 2005 Zevalin Available from: http://www.hc-sc.gc.ca/dhp- mps/prodpharma/activit/proj/sbd-smd/nd-ad-2005-zevalin-076192-e.html accessed January 15th 2007
11. Hume S P, Gunn R N and Jones T 1998 Pharmacological constraints associated with positron emission tomographic scanning of small laboratory animals Eur. J. Nucl. Med. 25 173-6
12. Iwata R 2002 Reference book for PET radiopharmaceuticals http://kakuyaku.cyric.tohoku.ac.jp/public/preface2002.html
13. Judenhofer M S, Catana C, Swann B K, Siegel S B, Jung W I, Nutt R E, Cherry S R, Claussen C D and Pichler B J 2007 PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet Radiology 244 807-14
14. 18F-labeled 1-[2-(4-alkoxy-3-methoxyphenyl)ethyl]-4-(3-phenylpropyl) piperazines as sigma receptor ligands for positron emission tomography studies Nucl. Med. Biol. 30 273-84
15. 186Re- hydroxyethylidene diphosphonate in patients with painful bone metastases of prostate or breast cancer J. Nucl. Med. 41 1689-94
16. 123I-radiopharmaceuticals for SPECT imaging Int. J. Radiat. Appl. Instrum. B 18 647-54
17. Kung H F, Kung M P and Choi S R 2003 Radiopharmaceuticals for single-photon emission computed tomography brain imaging Semin. Nucl. Med. 33 2-13
18. 123I-iodine monochloride as iodination reagent for synthesis of radiopharmaceuticals IV J. Nucl. Med. 13 266-73
19. Langstrom B, Bergstrom M, Hartvig P, Valind S and Watanabe Y 1995 Is PET a tool for drug evaluation? PET for Drug Development and Evaluation ed D Comar (Dordrecht: Kluwer)
20. Lawrence E O and Livingston M S 1932 The production of high speed light ions without the use of high voltages Phys. Rev. 40 19
21. Lawrence J H 1940 Nuclear physics and therapy: preliminary report on a new method for the treatment of leukemia and polycythemia Radiology 35 51
22. Levi H 1976 George Hevesy and his concept of radioactive indicators-in retrospect Eur. J. Nucl. Med. 1 3-10
23. 64Cu for tumor imaging and therapy J. Nucl. Med. 44 1284-92
24. Maxon H R, Schroder L E, Thomas S R, Hertzberg V S, Deutsch E A, Scher H I, Samaratunga R C, Libson K F, Williams C C and Moulton J S 1990 Re-186(Sn) HEDP for treatment of painful osseous metastases: initial clinical experience in 20 patients with hormone-resistant prostate cancer Radiology 176 155-9
25. 64Cu using a biomedical cyclotron J. Nucl. Med. Biol. 24 35-43
26. Okarvi S M 2001 Recent progress in fluorine-18 labeled peptide radiopharmaceuticals Eur. J. Nucl. Med. 28 929-38
27. Ruth T J 1994 Nuclear medicine Encyclopedia of Applied Physics vol 11 (New York: VCH) pp 513-41
28. Sossi V and Ruth T J 2005 MicroPET imaging: in vivo biochemistry in small animals J. Neural Transm. 112 319-30
29. 18F-FDG PET scans J. Nucl. Med. 42 1622-9
30. Yalow R S 1978 Radioimmunoassay: a probe for the fine structure of biologic system Science 200 1236-45
31. Burns H D, Gibson R E, Dannals R F and Siegl P K S 1993 Nuclear Imaging in Drug Discovery, Development and Approval (Boston: Birkhauser)
32. Diksic M and Reba R C (ed) 1990 Radiopharmaceuticals and Brain Pathology Studied with PET and SPECT (Boca Raton, FL: CRC Press)
33. Frost J J and Wagner H N (ed) 1990 Quantitative Imaging, Neuroreceptors, Neurotransmitters and Enzymes (New York: Raven)
34. Harbert J and da Roche A F G 1984 Textbook of Nuclear Medicine, Volume I: Basic Science 2nd edn (Philadelphia: Lea and Febiger)
35. Swanson D P, Chilton H M and Thrall J H 1990 Pharmaceuticals in Medical Imaging (New York: Macmillan)
36. Eckelman W C and Gibson R E 1993 The design of site-directed radiopharmaceuticals for use in drug discovery Nuclear Imaging in Drug Discovery, Development and Approval ed H D Burns et al (Boston: Birkhäuser) pp 113-34
37. Lyons S K 2005 Advances in imaging mouse tumour models in vivo J. Pathol. 205 194-205
38. Saha G B 1979 Fundamentals of Nuclear Pharmacy (New York: Springer)
39. Campbell B 1995 Drug development and positron emission tomography PET for Drug Development and Evaluation ed D Comar (Dordrecht: Kluwer)
40. Chatziioannou A F 2002 PET scanners dedicated to molecular imaging of small animal models Mol. Imaging Biol. 4 47-63
41. Cherry S R and Gambhir S S 2001 Use of positron emission tomography in animal research ILAR J. 42 219-32
42. Cherry S R 2001 Fundamentals of positron emission tomography and applications in preclinical drug development J. Clin. Pharmacol. 41 482-91
43. del Guerra A and Belcari N 2002 Advances in animal PET scanners Q. J. Nucl. Med. 46 35-47
44. Frese T, Rouze N C, Bouman C A, Sauer K and Hutchins G D 2003 Quantitative comparison of FBP, EM, and Bayesian reconstruction algorithms for the IndyPET scanner IEEE Trans. Med. Imaging 22 258-76
45. Herschman H R 2003 Molecular imaging: looking at problems, seeing solutions Science 302 605-8
46. Herschman H R 2004 PET reporter genes for noninvasive imaging of gene therapy, cell tracking and transgenic analysis Crit. Rev. Oncol./Hematol. 51 191-204
47. Hume S P, Gunn R N and Jones T 1998 Pharmacological constraints associated with positron emission tomographic scanning of small laboratory animals Eur. J. Nucl. Med. 25 173-6
48. Hume S P and Myers R 2002 Dedicated small animal scanners: a new tool for drug development? Curr. Pharm. Des. 8 1497-511
49. Jacobs A H et al 2003 PET-based molecular imaging in neuroscience Eur. J. Nucl. Med. Mol. Imaging 30 1051-65
50. Jeavons A P, Chandler R A and Car D 1999 A 3D HIDAC-PET Camera with Sub-millimetre resolution for imaging small animals IEEE Trans. Nucl. Sci. 46 468-73
51. Knoess C et al 2003 Performance evaluation of the microPET R4 PET scanner for rodents Eur. J. Nucl. Med. Mol. Imaging 30 737-47
52. Langstrom B, Bergstrom M, Hartvig P, Valind S and Watanabe Y 1995 Is PET a tool for drug evaluation? PET for Drug Development and Evaluation ed D Comar (Dordrecht: Kluwer)
53. Lecomte R et al 2004 Design considerations for a combined, APD-based μPET/μCT Scanner Proc. IEEE/MIC Meeting (Rome, Italy)
54. Myers R 2001 The biological application of small animal PET imaging Nucl. Med. Biol. 28 585-93
55. Okarvi S M 2001 Recent progress in fluorine-18 labeled peptide radiopharmaceuticals Eur. J. Nucl. Med. 28 929-38
56. Rowland D J, Lewis J S and Welch M J 2002 Molecular imaging: the application of small animal positron emission tomography J. Cell Biochem. Suppl. 39 110-5
57. Seemann M D 2005 Whole-body PET/MRI: the future in oncological imaging Technol. Cancer Res. Treat. 4 577-82
58. Seidel J, Vaquero J J and Green M V 2003 Resolution uniformity and sensitivity of the NIH ATLAS small animal PET scanner: comparison to simulated LSO scanners without depth-of-interaction capability IEEE Trans. Nucl. Sci. 50 1347-50
59. Sossi V and Ruth T J 2005 MicroPET imaging: in vivo biochemistry in small animals J. Neural Transm. 112 319-30
60. Tai Y C, Chatziioannou A F, Yang Y, Silverman R W, Meadors K, Siegel S, Newport D F, Stickel J R and Cherry S R 2003 MicroPET II: design, development and initial performance of an improved microPET scanner for small-animal imaging Phys. Med. Biol. 48 1519-37
61. Tsyganov E N, Antich P P, Kulkarni P V, Mason R P, Parkey R W, Seliounine S Y, Shay J W, Soesbe T C and Zinchenko A I 2004 Micro-SPECT combined with 3D optical imaging Proc. IEEE/MIC Meeting (Rome, Italy)
62. Weber S et al 1999 First results from MADPET-II: a novel detector and readout system for high resolution small animal PET IEEE Trans. Nucl. Sci. 46 1177-83
63. Woody C L et al 2004 The RatCAP Conscious Small Animal PET tomography Proc. IEEE/MIC Meeting (Rome, Italy)
64. Qaim S M and Coenen H H (ed) 2004 Advances in Nuclear and Radiochemistry (Jülich: Forschungzentrum, Jülich GmbH)
65. Albrecht A, Schultze U, Bello Bugallo P, Wydler H, Frossard E and Flühler H 2003 Behavior of a surface applied radionuclide and a dye tracer in structured and repacked soil monoliths J. Environ. Radioact. 68 47-64
66. Ban-nai T and Muramatsu Y 2002 Transfer factors of radioactive Cs, Sr, Mn, Co and Zn from Japanese soils to root and leaf of radish J. Environ. Radioact. 63 251-64
67. Brandtberga P-O, Bengtssonb J and Lundkvist H 2004 Distributions of the capacity to take up nutrients by Betula spp. and Picea abies in mixed stands Forest Ecol. Management 198 193-208
68. Reide Corbetta D, McKeeb B and Duncan D 2004 An evaluation of mobile mud dynamics in the Mississippi River deltaic region Mar. Geol. 209 91-112
69. Seebaugh D R, Goto D and Wallace W G 2005 Bioenhancement of cadmium transfer along a multi-level food chain Mar. Environ. Res. 59 473-91
70. 65,69mZn Sci. Total Environ. 287 13-30
71. Britto D T, Ruth T J, Lapi S and Kronzucker H J 2004 Cellular and whole-plant chloride dynamics in barley: insights into chloride-nitrogen interactions and salinity responses Planta 218 615-22
72. Britto D T and Kronzucker H J 2003 Trans-stimulation of efflux provides evidence for the cytosolic origin of tracer in the compartmental analysis of barley roots Funct. Plant Biol. 30 1233-8
73. Kaiser B N, Rawat S R, Siddiqi M Y, Masle J and Glass A D M 2002 Functional analysis of an Arabidopsis T-DNA 'knockout' of the high-affinity transporter AtAMT1 Plant Physiol. 130 1263-75
74. Kronzucker H J, Siddiqi M Y, Glass A D M and Britto D T 2003 Root ammonium transport efficiency as a determinant in forest colonization patterns: a hypothesis Physiol. Plant 117 164-70
75. Glass A D et al 2002 The regulation of nitrate and ammonium transport systems in plants J. Exp. Bot. 53 855-64 (Review)
76. Britto D T and Kronzucker H J 2001 Constancy of nitrogen turnover kinetics in the plant cell: insights into the integration of subcellular N fluxes Planta 213 175-81
77. Britto D T, Glass A D M, Kronzucker H J and Siddiqi M Y 2001 Cytosolic concentrations and transmembrane fluxes of : an analysis of a current controversy Plant Physiol. 125 523-6
78. Kronzucker H J, Britto D T, Davenport R J and Tester M 2001 Ammonium toxicity and the real cost of transport Trends Plant Sci. 6 335-7
79. Britto D T, Siddiqi M Y, Glass A D and Kronzucker H J 2001 Futile transmembrane cycling: a cellular hypothesis to explain ammonium toxicity in plants Proc. Natl Acad. Sci. USA 98 4255-8
80. Glass A D M et al 2001 Nitrogen transport in plants, with an emphasis on the regulation of fluxes to match plant demand J. Plant Nutrition Soil Sci. 164 199-207
81. Vidmar J J, Zhuo D, Siddiqi M Y, Schjoerring J K, Touraine B and Glass A D M 2000 Regulation of HvNRT2 expression and high-affinity nitrate influx in roots of Hordeum vulgare by ammonium and amino acids Plant Physiol. 123 307-18
82. Vidmar J J, Zhuo D, Siddiqi M Y and Glass A D M 2000 Isolation and characterization of HvNRT2.3 and HvNRT2.4, cDNAs encoding high-affinity nitrate transporters from roots of Hordeum vulgare Plant Physiol. 122 783-92
83. Kronzucker H J, Glass A D M, Siddiqi M Y and Kirk G J D 2000 Comparative kinetic analysis of ammonium and nitrate acquisition by tropical lowland rice: implications for rice cultivation and yield potential New Phytol. 145 471-6
84. Min X J, Siddiqi M Y, Guy R D, Glass A D M and Kronzucker H J 2000 A comparative kinetic analysis of nitrate and ammonium influx in two early-successional tree species of temperate and boreal forest ecosystems Plant Cell Environ. 23 321-8
85. Britto D T, Glass A D, Kronzucker H J and Siddiqi M Y 2001 Cytosolic concentrations and transmembrane fluxes of : an evaluation of recent proposals Plant Physiol. 125 523-6
86. Glass A D M et al 2001 Nitrogen transport in plants, with emphasis on the regulation of fluxes to match plant demand Pflanzen. Boden. 164 199-207
87. Touraine B and Glass A D M 1997 Nitrate and chlorate fluxes in the chl1-5 mutant of Arabidopsis thaliana: does the CHL1-5 gene encode a low affinity nitrate transporter? Plant Physiol. 114 137-44
88. Chen X, Gastaldi C, Siddiqi M Y and Glass A D M 1997 Growth of a lettuce crop at low ambient nutrient concentrations: a strategy designed to limit the potential for eutrophication J. Plant Nutrition 20 1403-17
89. Crawford N M and Glass A D M 1998 Molecular and physiological aspects of nitrate uptake in plants Trends Plant Sci. 3 381-95
90. Min X, Siddiqi M Y, Guy R D, Glass A D M and Kronzucker H J 1998 Induction of nitrate uptake and nitrate reductase in trembling aspen and lodgepole pine Plant Cell Environ. 21 1039-46
91. Kronzucker H J, Guy R D, Kirk K, Siddiqi M Y and Glass A D M 1998 Effects of hypoxia on uptake in rice roots: kinetics and compartmental analysis Plant Physiol. 116 581-7
92. Kronzucker H J, Siddiqi M Y and Glass A D M 1997 Conifer root discrimination against soil nitrate and the ecology of forest succession Nature 385 59-61
93. Glass A D M, Erner Y, Kronzucker H J, Schjoerring J K, Siddiqi M Y and Wang M Y 1997 Ammonium fluxes into plant roots: energetics, kinetics and regulation Z. Pflanzen. Boden. 160 261-8
94. Glass A D M et al 1999 Inorganic nitrogen absorption by plant roots: physiology and molecular biology Plant Nutrition Molecular Biology and Genetics ed G Gissel-Nielsen and A Jensen (Wageningen: Kluwer) pp 1-16
95. Min X, Siddiqi M Y, Guy R D, Glass A D M and Kronzucker H J 1999 A comparative study of fluxes and compartmentation of nitrate and ammonium in early successional tree species Plant Cell Environ. 22 821-30
96. Johnson R R, Glass A D M, Kronzucker H J, Gelbart Z, Venczel E, Paul M, Berkovits D, Cavan A, Kashiv Y and Ghelberg S 1997 Measurement of aluminum transport in wheat at the cellular level Nucl. Instrum. Methods B 123 283-6
97. Wang M Y, Glass A, Shaff J E and Kochian L V 1994 Ammonium uptake by rice roots: III. Electrophysiology Plant Physiol. 104 899-906
98. Wang M Y, Siddiqi M Y, Ruth T J and Glass A 1993 Ammonium uptake by rice roots: II. Kinetics of Influx across the plasmalemma Plant Physiol. 103 1259-67
99. Wang M Y, Siddiqi M Y, Ruth T J and Glass A 1993 Ammonium uptake by rice roots: I. Fluxes and subcellular distribution of Plant Physiol. 103 1249-58
100. King B J, Siddiqi M Y, Ruth T J, Warner R L and Glass A 1993 Feedback regulation of nitrate influx in barley roots by nitrate, nitrite, and ammonium Plant Physiol. 102 1279-86
101. Kronzucker H J, Siddiqi M Y and Glass A 1995 Analysis of efflux in spruce roots (a test case for phase identification in compartmental analysis Plant Physiol. 109 481-90
102. Kronzucker H J, Glass A D and Yaeesh Siddiqi M 1999 Inhibition of nitrate uptake by ammonium in barley: analysis of component fluxes Plant Physiol. 120 283-92
103. Kronzucker H J, Siddiqi M Y, Glass A D and Kirk G J 1999 Nitrate-ammonium synergism in rice: a subcellular flux analysis Plant Physiol. 119 1041-6
104. Kronzucker H J, Kirk G J D, Yaeesh Siddiqi M and Glass A D M 1998 Effects of hypoxia on fluxes in rice roots: kinetics and compartmental analysis Plant Physiol. 116 581-7
105. 3-influx Plant Physiol. 93 1426-32
106. Glass A D M, Siddiqi M Y, Ruth T J and Rufty T W 1990 Studies of the uptake of nitrate in barley: 2. Energetics Plant Physiol. 93 1585-9
107. + chloride salts J. Plant Nutr. 15 959-75
108. Babst B A, Ferrieri R A, Gray D W, Lerdau M, Schlyer D J, Schueller M, Thorpe M R and Orians C M 2005 Jasmonic acid induces rapid changes in carbon transport and partitioning in Populus New Phytol. 167 63-72
109. 11C)-imaging: methyl jasmonate moves in both phloem and xylem, promotes transport of jasmonate, and of photoassimilate even after proton transport is decoupled Planta 226 541-51
110. Ferrieri A P, Thorpe M R and Ferrieri R A 2006 Stimulating natural defenses in poplar clones (OP-367) increases plant metabolism of carbon tetrachloride Int. J. Phytoremediation 8 233-43
111. Babst B A, Ferrieri R A, Gray D W, Lerdau M, Schlyer D J, Schueller M, Thorpe M R and Orians C M 2005 Jasmonic acid induces rapid changes in carbon transport and partitioning in Populus New Phytol. 167 63-72