메뉴 건너뛰기




Volumn 250, Issue 1, 2009, Pages 95-102

Quantification of liver fat content: Comparison of triple-echo chemical shift gradient-echo imaging and in vivo proton MR spectroscopy

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BODY WEIGHT; BREATH HOLDING; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; FAT CONTENT; FATTY LIVER; FEMALE; HUMAN; IMAGING SYSTEM; INTERMETHOD COMPARISON; LIVER; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; AGED; COMPARATIVE STUDY; COMPUTER PROGRAM; ECHO PLANAR IMAGING; IMAGE ENHANCEMENT; IMAGE PROCESSING; MATHEMATICAL COMPUTING; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

EID: 58149359688     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2493080217     Document Type: Article
Times cited : (168)

References (54)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 2
    • 34548306754 scopus 로고    scopus 로고
    • Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: Present and future
    • Wieckowska A, McCullough AJ, Feldstein AE. Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future. Hepatology 2007;46:582-589.
    • (2007) Hepatology , vol.46 , pp. 582-589
    • Wieckowska, A.1    McCullough, A.J.2    Feldstein, A.E.3
  • 3
    • 34547514221 scopus 로고    scopus 로고
    • Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
    • Gastaldelli A, Cusi K, Pettiti M, et al. Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects. Gastroenterology 2007;133:496-506.
    • (2007) Gastroenterology , vol.133 , pp. 496-506
    • Gastaldelli, A.1    Cusi, K.2    Pettiti, M.3
  • 5
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzen LE, Mathiesen UL, et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006;44:865-873.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M.1    Franzen, L.E.2    Mathiesen, U.L.3
  • 7
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma
    • Bugianesi E, Leone N, Vanni E, et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002;123:134-140.
    • (2002) Gastroenterology , vol.123 , pp. 134-140
    • Bugianesi, E.1    Leone, N.2    Vanni, E.3
  • 8
    • 33745146832 scopus 로고    scopus 로고
    • Hepatic macrosteatosis: Predicting appropriateness of liver donation by using MR imaging - correlation with histopathologic findings
    • Kim SH, Lee JM, Han JK, et al. Hepatic macrosteatosis: predicting appropriateness of liver donation by using MR imaging - correlation with histopathologic findings. Radiology 2006;240:116-129.
    • (2006) Radiology , vol.240 , pp. 116-129
    • Kim, S.H.1    Lee, J.M.2    Han, J.K.3
  • 9
    • 13944279982 scopus 로고    scopus 로고
    • Understanding the meaning of fat in the liver
    • McCormack L, Clavien PA. Understanding the meaning of fat in the liver. Liver Transpl 2005;11:137-139.
    • (2005) Liver Transpl , vol.11 , pp. 137-139
    • McCormack, L.1    Clavien, P.A.2
  • 10
    • 13944283869 scopus 로고    scopus 로고
    • The hepatic regeneration power of mild steatotic grafts is not impaired in living-donor liver transplantation
    • Cho JY, Suh KS, Kwon CH, et al. The hepatic regeneration power of mild steatotic grafts is not impaired in living-donor liver transplantation. Liver Transpl 2005;11:210-217.
    • (2005) Liver Transpl , vol.11 , pp. 210-217
    • Cho, J.Y.1    Suh, K.S.2    Kwon, C.H.3
  • 11
    • 32844458032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it
    • Begriche K, Igoudjil A, Pessayre D, Fromenty B. Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion 2006;6:1-28.
    • (2006) Mitochondrion , vol.6 , pp. 1-28
    • Begriche, K.1    Igoudjil, A.2    Pessayre, D.3    Fromenty, B.4
  • 12
    • 10844240700 scopus 로고    scopus 로고
    • Hepatic triglyceride content and its relation to body adiposity: A magnetic resonance imaging and proton magnetic resonance spectroscopy study
    • Thomas EL, Hamilton G, Patel N, et al. Hepatic triglyceride content and its relation to body adiposity: a magnetic resonance imaging and proton magnetic resonance spectroscopy study. Gut 2005;54:122-127.
    • (2005) Gut , vol.54 , pp. 122-127
    • Thomas, E.L.1    Hamilton, G.2    Patel, N.3
  • 13
    • 18544403656 scopus 로고    scopus 로고
    • Noninvasive in vivo quantitative assessment of fat content in human liver
    • Ricci C, Longo R, Gioulis E, et al. Noninvasive in vivo quantitative assessment of fat content in human liver. J Hepatol 1997;27:108-113.
    • (1997) J Hepatol , vol.27 , pp. 108-113
    • Ricci, C.1    Longo, R.2    Gioulis, E.3
  • 14
    • 34447509617 scopus 로고    scopus 로고
    • Unenhanced CT for assessment of macrovesicular hepatic steatosis in living liver donors: Comparison of visual grading with liver attenuation index
    • Lee SW, Park SH, Kim KW, et al. Unenhanced CT for assessment of macrovesicular hepatic steatosis in living liver donors: comparison of visual grading with liver attenuation index. Radiology 2007;244:479-485.
    • (2007) Radiology , vol.244 , pp. 479-485
    • Lee, S.W.1    Park, S.H.2    Kim, K.W.3
  • 15
    • 27744582271 scopus 로고    scopus 로고
    • Hepatic fat fraction: MR imaging for quantitative measurement and display- early experience
    • Hussain HK, Chenevert TL, Londy FJ, et al. Hepatic fat fraction: MR imaging for quantitative measurement and display- early experience. Radiology 2005;237:1048-1055.
    • (2005) Radiology , vol.237 , pp. 1048-1055
    • Hussain, H.K.1    Chenevert, T.L.2    Londy, F.J.3
  • 16
    • 27144532730 scopus 로고    scopus 로고
    • Accuracy of liver fat quantification at MR imaging: Comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques-initial experience
    • Qayyum A, Goh JS, Kakar S, Yeh BM, Merriman RB, Coakley FV. Accuracy of liver fat quantification at MR imaging: comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques-initial experience. Radiology 2005;237:507-511.
    • (2005) Radiology , vol.237 , pp. 507-511
    • Qayyum, A.1    Goh, J.S.2    Kakar, S.3    Yeh, B.M.4    Merriman, R.B.5    Coakley, F.V.6
  • 17
    • 33846452882 scopus 로고    scopus 로고
    • Liver fat: Effect of hepatic iron deposition on evaluation with opposed-phase MR imaging
    • Westphalen AC, Qayyum A, Yeh BM, et al. Liver fat: effect of hepatic iron deposition on evaluation with opposed-phase MR imaging. Radiology 2007;242:450-455.
    • (2007) Radiology , vol.242 , pp. 450-455
    • Westphalen, A.C.1    Qayyum, A.2    Yeh, B.M.3
  • 18
    • 37149001609 scopus 로고    scopus 로고
    • Increased intrahepatic triglyceride is associated with peripheral insulin resistance: In vivo MR imaging and spectroscopy studies
    • Hwang JH, Stein DT, Barzilai N, et al. Increased intrahepatic triglyceride is associated with peripheral insulin resistance: in vivo MR imaging and spectroscopy studies. Am J Physiol Endocrinol Metab 2007;293:E1663-E1669.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Hwang, J.H.1    Stein, D.T.2    Barzilai, N.3
  • 19
    • 0029300637 scopus 로고
    • Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis
    • Longo R, Pollesello P, Ricci C, et al. Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis. J Magn Reson Imaging 1995;5:281-285.
    • (1995) J Magn Reson Imaging , vol.5 , pp. 281-285
    • Longo, R.1    Pollesello, P.2    Ricci, C.3
  • 20
    • 0036310037 scopus 로고    scopus 로고
    • The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
    • Mayerson AB, Hundal RS, Dufour S, et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes 2002;51:797-802.
    • (2002) Diabetes , vol.51 , pp. 797-802
    • Mayerson, A.B.1    Hundal, R.S.2    Dufour, S.3
  • 21
    • 0036312905 scopus 로고    scopus 로고
    • Fat accumulation in the liver is associated with defects in insulin suppression ofglucose production and serumfree fattyacids independent of obesity in normal men
    • Seppala-Lindroos A, Vehkavaara S, Hakkinen AM, et al. Fat accumulation in the liver is associated with defects in insulin suppression ofglucose production and serumfree fattyacids independent of obesity in normal men. J Clin Endocrinol Metab 2002;87:3023-3028.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3023-3028
    • Seppala-Lindroos, A.1    Vehkavaara, S.2    Hakkinen, A.M.3
  • 22
    • 0033007207 scopus 로고    scopus 로고
    • Measurement of intracellular triglyceride stores by H spectroscopy: Validation in vivo
    • Szczepaniak LS, Babcock EE, Schick F, et al. Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. Am J Physiol 1999;276:E977-E989.
    • (1999) Am J Physiol , vol.276
    • Szczepaniak, L.S.1    Babcock, E.E.2    Schick, F.3
  • 23
    • 62649138904 scopus 로고    scopus 로고
    • Szczepaniak LS, Nurenberg P, Leonard D, et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population
    • Szczepaniak LS, Nurenberg P, Leonard D, et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population.
  • 26
    • 0036730974 scopus 로고    scopus 로고
    • Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes
    • Tiikkainen M, Tamminen M, Hakkinen AM, et al. Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes. Obes Res 2002;10:859-867.
    • (2002) Obes Res , vol.10 , pp. 859-867
    • Tiikkainen, M.1    Tamminen, M.2    Hakkinen, A.M.3
  • 27
    • 37349086107 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy ofhepatic lipid content and associated risk factors in HIV infection
    • Hadigan C, Liebau J, Andersen R, Holalkere NS, Sahani DV. Magnetic resonance spectroscopy ofhepatic lipid content and associated risk factors in HIV infection. J Acquir Immune Defic Syndr 2007;46:312-317.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 312-317
    • Hadigan, C.1    Liebau, J.2    Andersen, R.3    Holalkere, N.S.4    Sahani, D.V.5
  • 28
    • 20244369267 scopus 로고    scopus 로고
    • Liver fat content measured by magnetic resonance spectroscopy at 3.0 tesla independently correlates with plasminogen activator inhibitor-1 and body mass index in type 2 diabetic subjects
    • Ishii M, Yoshioka Y, Ishida W, et al. Liver fat content measured by magnetic resonance spectroscopy at 3.0 tesla independently correlates with plasminogen activator inhibitor-1 and body mass index in type 2 diabetic subjects. Tohoku J Exp Med 2005;206:23-30.
    • (2005) Tohoku J Exp Med , vol.206 , pp. 23-30
    • Ishii, M.1    Yoshioka, Y.2    Ishida, W.3
  • 29
    • 19444368910 scopus 로고    scopus 로고
    • Feasibility of quantitative intrahepatic lipid imaging applied to the magnetic resonance dual gradient echo sequence
    • Kawamitsu H, Kaji Y, Ohara T, Sugimura K. Feasibility of quantitative intrahepatic lipid imaging applied to the magnetic resonance dual gradient echo sequence. Magn Reson Med Sci 2003;2:47-50.
    • (2003) Magn Reson Med Sci , vol.2 , pp. 47-50
    • Kawamitsu, H.1    Kaji, Y.2    Ohara, T.3    Sugimura, K.4
  • 30
    • 39349106660 scopus 로고    scopus 로고
    • Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents
    • Liska D, Dufour S, Zern TL, et al. Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents. PLoS ONE 2007;2:e569.
    • (2007) PLoS ONE , vol.2
    • Liska, D.1    Dufour, S.2    Zern, T.L.3
  • 31
    • 33645786275 scopus 로고    scopus 로고
    • Hepatic lipid accumulation in healthy subjects: A comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy
    • Machann J, Thamer C, Schnoedt B, et al. Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy. Magn Reson Med 2006;55:913-917.
    • (2006) Magn Reson Med , vol.55 , pp. 913-917
    • Machann, J.1    Thamer, C.2    Schnoedt, B.3
  • 33
    • 33847613579 scopus 로고    scopus 로고
    • Habitual physical activity is associated with intrahepatic fat content in humans
    • Perseghin G, Lattuada G, De Cobelli F, et al. Habitual physical activity is associated with intrahepatic fat content in humans. Diabetes Care 2007;30:683-688.
    • (2007) Diabetes Care , vol.30 , pp. 683-688
    • Perseghin, G.1    Lattuada, G.2    De Cobelli, F.3
  • 34
    • 33750428930 scopus 로고    scopus 로고
    • Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging
    • Sijens PE, Smit GP, Borgdorff MA, Kappert P, Oudkerk M. Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging. J Hepatol 2006;45:851-855.
    • (2006) J Hepatol , vol.45 , pp. 851-855
    • Sijens, P.E.1    Smit, G.P.2    Borgdorff, M.A.3    Kappert, P.4    Oudkerk, M.5
  • 35
    • 17544385213 scopus 로고    scopus 로고
    • MR proton spectroscopy in liver examinations of healthy individuals in vivo
    • Tarasow E, Siergiejczyk L, Panasiuk A, et al. MR proton spectroscopy in liver examinations of healthy individuals in vivo. Med Sci Monit 2002;8:MT36-MT40.
    • (2002) Med Sci Monit , vol.8
    • Tarasow, E.1    Siergiejczyk, L.2    Panasiuk, A.3
  • 36
    • 33746220435 scopus 로고    scopus 로고
    • 1H MR spectroscopy of the brain: Absolute quantification of metabolites
    • Jansen JF, Backes WH, Nicolay K, Kooi ME. 1H MR spectroscopy of the brain: absolute quantification of metabolites. Radiology 2006;240:318-332.
    • (2006) Radiology , vol.240 , pp. 318-332
    • Jansen, J.F.1    Backes, W.H.2    Nicolay, K.3    Kooi, M.E.4
  • 37
    • 0034989141 scopus 로고    scopus 로고
    • Java-based graphical user interface for the MRUI quantitation package
    • Naressi A, Couturier C, Devos JM, et al. Java-based graphical user interface for the MRUI quantitation package. MAGMA 2001;12:141-152.
    • (2001) MAGMA , vol.12 , pp. 141-152
    • Naressi, A.1    Couturier, C.2    Devos, J.M.3
  • 38
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307-310.
    • (1986) Lancet , vol.1 , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 39
    • 0024521543 scopus 로고
    • A concordance correlation coefficient to evaluate reproducibility
    • Lin LI. A concordance correlation coefficient to evaluate reproducibility. Biometrics 1989;45:255-268.
    • (1989) Biometrics , vol.45 , pp. 255-268
    • Lin, L.I.1
  • 40
    • 40449095940 scopus 로고    scopus 로고
    • Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point dixon and three-point IDEAL
    • Kim H, Taksali SE, Dufour S, et al. Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point dixon and three-point IDEAL. Magn Reson Med 2008;59:521-527.
    • (2008) Magn Reson Med , vol.59 , pp. 521-527
    • Kim, H.1    Taksali, S.E.2    Dufour, S.3
  • 42
    • 43949144276 scopus 로고    scopus 로고
    • Noninvasive assessment of hepatic lipid composition: Advancing understanding and management of fatty liver disorders
    • Johnson NA, Walton DW, Sachinwalla T, et al. Noninvasive assessment of hepatic lipid composition: advancing understanding and management of fatty liver disorders. Hepatology 2008;47:1513-1523.
    • (2008) Hepatology , vol.47 , pp. 1513-1523
    • Johnson, N.A.1    Walton, D.W.2    Sachinwalla, T.3
  • 43
    • 1342330052 scopus 로고    scopus 로고
    • MR imaging relaxation times of abdominal and pelvic tissues measured in vivo at 3.0 T: Preliminary results
    • de Bazelaire CM, Duhamel GD, Rofsky NM, Alsop DC. MR imaging relaxation times of abdominal and pelvic tissues measured in vivo at 3.0 T: preliminary results. Radiology 2004;230:652-659.
    • (2004) Radiology , vol.230 , pp. 652-659
    • de Bazelaire, C.M.1    Duhamel, G.D.2    Rofsky, N.M.3    Alsop, D.C.4
  • 44
    • 33747047274 scopus 로고    scopus 로고
    • Statins and hepatic steatosis: Perspectives from the Dallas Heart Study
    • Browning JD. Statins and hepatic steatosis: perspectives from the Dallas Heart Study. Hepatology 2006;44:466-471.
    • (2006) Hepatology , vol.44 , pp. 466-471
    • Browning, J.D.1
  • 45
    • 42949178538 scopus 로고    scopus 로고
    • Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects
    • Korenblat KM, Fabbrini E, Mohammed BS, Klein S. Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 2008;134:1369-1375.
    • (2008) Gastroenterology , vol.134 , pp. 1369-1375
    • Korenblat, K.M.1    Fabbrini, E.2    Mohammed, B.S.3    Klein, S.4
  • 46
    • 38149030206 scopus 로고    scopus 로고
    • Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects
    • Kotronen A, Juurinen L, Hakkarainen A, et al. Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects. Diabetes Care 2008;31:165-169.
    • (2008) Diabetes Care , vol.31 , pp. 165-169
    • Kotronen, A.1    Juurinen, L.2    Hakkarainen, A.3
  • 47
    • 41349098551 scopus 로고    scopus 로고
    • Assessment of the variations in fat content in normal liver using a fast MR imaging method in comparison with results obtained by spectroscopic imaging
    • Irwan R, Edens MA, Sijens PE. Assessment of the variations in fat content in normal liver using a fast MR imaging method in comparison with results obtained by spectroscopic imaging. Eur Radiol 2008;18:806-813.
    • (2008) Eur Radiol , vol.18 , pp. 806-813
    • Irwan, R.1    Edens, M.A.2    Sijens, P.E.3
  • 48
    • 34547673500 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients
    • Targher G, Bertolini L, Rodella S, et al. Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients. Diabetes Care 2007;30:2119-2121.
    • (2007) Diabetes Care , vol.30 , pp. 2119-2121
    • Targher, G.1    Bertolini, L.2    Rodella, S.3
  • 49
    • 0032881292 scopus 로고    scopus 로고
    • Hepatic iron and nonalcoholic fatty liver disease
    • Younossi ZM, Gramlich T, Bacon BR, et al. Hepatic iron and nonalcoholic fatty liver disease. Hepatology 1999;30:847-850.
    • (1999) Hepatology , vol.30 , pp. 847-850
    • Younossi, Z.M.1    Gramlich, T.2    Bacon, B.R.3
  • 51
    • 39549097104 scopus 로고    scopus 로고
    • Liver fat and iron at in-phase and opposed-phase MR imaging [letter]
    • Alustiza JM, Castiella A. Liver fat and iron at in-phase and opposed-phase MR imaging [letter]. Radiology 2008;246:641.
    • (2008) Radiology , vol.246 , pp. 641
    • Alustiza, J.M.1    Castiella, A.2
  • 52
    • 20444443042 scopus 로고    scopus 로고
    • Sampling variability of liver biopsy in nonalcoholic fatty liver disease
    • Ratziu V, Charlotte F, Heurtier A, et al. Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastroenterology 2005;128:1898-1906.
    • (2005) Gastroenterology , vol.128 , pp. 1898-1906
    • Ratziu, V.1    Charlotte, F.2    Heurtier, A.3
  • 53
    • 1942421659 scopus 로고    scopus 로고
    • Assessment of donor liver steatosis: Pathologist or automated software?
    • Marsman H, Matsushita T, Dierkhising R, et al. Assessment of donor liver steatosis: pathologist or automated software? Hum Pathol 2004;35:430-435.
    • (2004) Hum Pathol , vol.35 , pp. 430-435
    • Marsman, H.1    Matsushita, T.2    Dierkhising, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.