The phosphorylation of survivin Thr34 by p34cdc2 in carcinogenesis of oral submucous fibrosis

Oncology Reports

Volumn 20, Issue 5, 2008, Pages 1085-1091

  Zhou, Shanghui ^a   Li, Lili ^b   Jian, Xinchun ^a   Ou, Xinrong ^a   Jiang, Haiying ^c   Yao, Zhigang ^a   Xu, Chunjiao ^a   Peng, Jieying ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Central South University   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Oral squamous cell carcinoma; Oral submucous fibrosis; Phosphorylation; Survivin

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; SURVIVIN; THREONINE; BIRC5 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER SURGERY; CARCINOGENESIS; CELL DIVISION; CELL NUCLEUS; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MAJOR CLINICAL STUDY; MALIGNANT TRANSFORMATION; MOUTH CARCINOMA; MOUTH DISEASE; MOUTH MUCOSA; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA; STAINING; WESTERN BLOTTING; CELL TRANSFORMATION; METABOLISM; MOUTH TUMOR; PHOSPHORYLATION; PRECANCER;

BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CDC2 PROTEIN KINASE; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MICROTUBULE-ASSOCIATED PROTEINS; MOUTH NEOPLASMS; NEOPLASM PROTEINS; ORAL SUBMUCOUS FIBROSIS; PHOSPHORYLATION; PRECANCEROUS CONDITIONS;

EID: 58149357598     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000113     Document Type: Article

References (30)

1. Scully C: Oral precancer: preventive and medical approaches to management. Eur J Cancer B Oral Oncol 31B: 16-26, 1995.
2. Schepman K, der Meij E, Smeele L and der Waal I: Concomitant leukoplakia in patients with oral squamous cell carcinoma. Oral Dis 5: 206-209, 1999.
3. Pindborg JJ and Sirsat SM: Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol 22: 764-779, 1966.
4. Zhang X and Reichart PA: A review of betel quid chewing, oral cancer and precancer in Mainland China. Oral Oncol 43: 424-430, 2007.
5. Gupta PC, Sinor PN, Bhonsle RB, Pawar VS and Mehta HC: Oral submucous fibrosis in India: a new epidemic? Natl Med J India 11: 113-116, 1998.
6. Murti PR, Bhonsle RB, Pindborg JJ, Daftary DK, Gupta PC and Mehta FS: Malignant transformation rate in oral submucous fibrosis over a 17-year period. Community Dent Oral Epidemiol 13: 340-341, 1985.
7. Jian XC, Shen ZH and Liu SF: Oral submucous fibrosis-case reporters. J Clin Stomatol 1: 12-13, 1985. (In Chinese)
8. Gao YJ, Ling TY, Yin xm, Yao ZG and Tang JQ: A retrospective study of malignant transformation of oral submucous fibrosis. J Clin Stomatol 21: 119-120, 2005.
9. Altieri DC: Survivin, cancer networks and pathway-directed drug discovery. Nat Rev Cancer 8: 61-70, 2008.
10. Pennati M, Folini M and Zaffaroni N: Targeting survivin in cancer therapy: fulfilled promises and open questions. Carcinogenesis 28: 1133-1139, 2007.
11. Li F and Ling X: Survivin study: an update of 'what is the next wave'? J Cell Physiol 208: 476-486, 2006.
12. O'Connor DS, Grossman D, Plescia J, Li F, Zhang H, Villa A, Tognin S, Marchisio PC and Altieri DC: Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci USA 97: 13103-13107, 2000.
13. Dohi T, Xia F and Altieri DC: Compartmentalized phosphorylation of IAP by protein kinase A regulates cytoprotection. Mol Cell 27: 17-28, 2007.
14. Wheatley SP, Barrett RM, Andrews PD, Medema RH, Morley SJ, Swedlow JR and Lens SM: Phosphorylation by aurora-B negatively regulates survivin function during mitosis. Cell Cycle 6: 1220-1230, 2007.
15. Tanaka C, Uzawa K, Shibahara T, Yokoe H, Noma H and Tanzawa H: Expression of an inhibitor of apoptosis, survivin, in oral carcinogenesis. J Dent Res 82: 607-611, 2003.
16. Lo Muzio L, Pannone G, Staibano S, Mignogna MD, Rubini C, Mariggio MA, Procaccini M, Ferrari F, De Rosa G and Altieri DC: Survivin expression in oral squamous cell carcinoma. Br J Cancer 89: 2244-2248, 2003.
17. Lo Muzio L, Pannone G, Leonardi R, Staibano S, Mignogna MD, De Rosa G, Kudo Y, Takata T and Altieri DC: Survivin, a potential early predictor of tumor progression in the oral mucosa. J Dent Res 82: 923-928, 2003.
18. Pindborg JJ, Reichart PA and Smith CJ: Histological Typing of Cancer and Precancer of the Oral Mucosa. 2nd edition, Springer-Verlag, Berlin, 1997.
19. Lu CD, Altieri DC and Tanigawa N: Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res 58: 1808-1812, 1998.
20. Jones MK, Padilla OR, Webb NA and Norng M: The antiapoptosis protein, survivin, mediates gastric epithelial cell cytoprotection against ethanol-induced injury via activation of the p34(cdc2) cyclin-dependent kinase. J Cell Physiol (In press).
21. Wall NR, O'Connor DS, Plescia J, Pommier Y and Altieri DC: Suppression of survivin phosphorylation on Thr34 by flavopiridol enhances tumor cell apoptosis. Cancer Res 63: 230-235, 2003.
22. Salz W, Eisenberg D, Plescia J, Garlick DS, Weiss RM, Wu XR, Sun TT and Altieri DC: A survivin gene signature predicts aggressive tumor behavior. Cancer Res 65: 3531-3534, 2005.
23. Zhang M, Latham DE, Delaney MA and Chakravarti A: Survivin mediates resistance to antiandrogen therapy in prostate cancer. Oncogene 24: 2474-2482, 2005.
24. Knauer SK, Bier C, Habtemichael N and Stauber RH: The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function. EMBO Rep 7: 1259-1265, 2006.
25. Stauber RH, Mann W and Knauer SK: Nuclear and cytoplasmic survivin: molecular mechanism, prognostic, and therapeutic potential. Cancer Res 67: 5999-6002, 2007.
26. Engels K, Knauer SK, Metzler D, Simf C, Struschka O, Bier C, Mann W, Kovacs AF and Stauber RH: Dynamic intracellular survivin in oral squamous cell carcinoma: underlying molecular mechanism and potential as an early prognostic marker. J Pathol 211: 532-540, 2007.
27. Wada S, Yue L and Furuta I: Prognostic significance of p34cdc2 expression in tongue squamous cell carcinoma. Oral Oncol 40: 164-169, 2004.
28. Harada H, Omura K, Nakajima Y, Hasegawa S and Mogi S: Cyclin B1 is useful to predict occult cervical lymph node metastases in tongue carcinoma. J Exp Clin Cancer Res 25: 351-356, 2006.
29. Pannone G, Bufo P, Serpico R, Rubini C, Zamparese R, Corsi F, Pedicillo MC, Pannone G, Staibano S, De Rosa G and Lo Muzio L: Survivin phosphorylation and M-phase promoting factor in oral carcinogenesis. Histol Histopathol 22: 1241-1249, 2007.
30. Ruchaud S, Carmena M and Earnshaw WC: Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol 8: 798-812, 2007.