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For a discussion on the mechanism of olefin isomerization in metathesis reactions, see
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It must be noted that two-step yields of 4 from 2 via 6 were better than those via 3 with the exception of the special case of 4f, see: Ref. 9.
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58149309751
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The mesylated phenol was obtained under the conditions
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The mesylated phenol was obtained under the conditions.
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58149292768
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The reason why we chose 2h and 2i as substrates to investigate these sequential experiments is that we observed that both intermediates 6h and 6i were somewhat unstable to isolation.
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The reason why we chose 2h and 2i as substrates to investigate these sequential experiments is that we observed that both intermediates 6h and 6i were somewhat unstable to isolation.
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Attempts to obtain 8f from 6f at once were unsuccessful. For example, Swern oxidation of 6f gave a mixture of 4f, 5f (major), and 8f.
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Attempts to obtain 8f from 6f at once were unsuccessful. For example, Swern oxidation of 6f gave a mixture of 4f, 5f (major), and 8f.
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58149307253
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The cyclized product 6b is also a potential precursor of resorcinol derivative. However, the synthesis of 8b from 6b was unfortunately unsuccessful. Although we have screened various oxidation conditions, the formation of phenol derivative 5b preferentially occurred.
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The cyclized product 6b is also a potential precursor of resorcinol derivative. However, the synthesis of 8b from 6b was unfortunately unsuccessful. Although we have screened various oxidation conditions, the formation of phenol derivative 5b preferentially occurred.
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