Prospective study of natural killer cell phenotype in recurrent hepatitis C virus infection following liver transplantation

Journal of Hepatology

Volumn 50, Issue 2, 2009, Pages 314-322

  Varchetta, Stefania ^a   Oliviero, Barbara ^a   Francesca Donato, M ^b   Agnelli, Francesca ^b   Rigamonti, Cristina ^b   Paudice, Enrica ^a   Arosio, Eliana ^b   Berra, Mauro ^b   Rossi, Giorgio ^b   Tinelli, Carmine ^a   Fagnoni, Francesco F ^c   Colombo, Massimo ^b   Mavilio, Domenico ^d   Mondelli, Mario U ^a  

^a FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^b Fondazione Policlinico Mangiagalli Regina Elena   (Italy)

^c IRCCS   (Italy)

^d HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

Innate immunity; Liver transplantation; Natural killer cells

Indexed keywords

ALANINE AMINOTRANSFERASE; CD94 ANTIGEN; CYCLOSPORIN A; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; PEGINTERFERON; RIBAVIRIN; STEROID; TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HEPATITIS C; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; LIVER DISEASE; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; NATURAL KILLER CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECURRENT DISEASE; T LYMPHOCYTE;

ADULT; AGED; ANTIGENS, CD56; FEMALE; HEPATITIS C; HUMANS; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROSPECTIVE STUDIES; RECURRENCE;

EID: 58149295512     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2008.10.018     Document Type: Article

References (37)

1. Berenguer M. Systematic review of the treatment of established recurrent hepatitis C with pegylated interferon in combination with ribavirin. J Hepatol 49 (2008) 274-287
2. Weston S.J., Leistikow R.L., Reddy K.R., Torres M., Wertheimer A.M., Lewinsohn D.M., et al. Reconstitution of hepatitis C virus-specific T-cell mediated immunity after liver transplantation. Hepatology 41 (2005) 72-81
3. Gruener N.H., Jung M.C., Ulsenheimer A., Gerlach J.T., Zachoval R., Diepolder H.M., et al. Analysis of a successful HCV-specific CD8+ T cell response in patients with recurrent HCV-infection after orthotopic liver transplantation. Liver Transpl 10 (2004) 1487-1496
4. Rosen H.R., Doherty D.G., Madrigal-Estebas L., O'Farrelly C., and Golden-Mason L. Pretransplantation CD56+ innate lymphocyte populations associated with severity of hepatitis C recurrence. Liver Transpl 14 (2008) 31-40
5. Doherty D.G., and O'Farrelly C. Innate and adaptive lymphoid cells in the human liver. Immunol Rev 174 (2000) 5-20
6. Szabo G., Chang S., and Dolganiuc A. Altered innate immunity in chronic hepatitis C infection - cause or effect?. Hepatology 46 (2007) 1279-1290
7. Corado J., Toro F., Rivera H., Bianco N.E., Deibis L., and De Sanctis J.B. Impairment of natural killer (NK) cytotoxic activity in hepatitis C virus (HCV) infection. Clin Exp Immunol 109 (1997) 451-457
8. Pár G., Rukavina D., Podack E.R., Horányi M., Szekeres-Barthó J., Hegedüs G., et al. Decrease in CD3-negative-CD8dim(+) and Vdelta2/Vgamma9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity is associated with chronic hepatitis C virus infection. J Hepatol 37 (2002) 514-522
9. Meier U.C., Owen R.E., Taylor E., Worth A., Naoumov N., Willberg C., et al. Shared alterations in NK cell frequency, phenotype, and function in chronic human immunodeficiency virus and hepatitis C virus infections. J Virol 79 (2005) 12365-12374
10. Golden-Mason L., Madrigal-Estebas L., McGrath E., Conroy M.J., Ryan E.J., Hegarty J.E., et al. Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure. Gut 57 (2008) 1121-1128
11. Morishima C., Paschal D.M., Wang C.C., Yoshihara C.S., Wood B.L., Yeao A.E., et al. Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing. Hepatology 43 (2006) 573-580
12. Düesberg U., Schneiders A.M., Flieger D., Inchauspé G., Sauerbruch T., and Spengler U. Natural cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC) is not impaired in patients suffering from chronic hepatitis C. J Hepatol 35 (2001) 650-657
13. Demetris A.J., Eghtesad B., Marcos A Ruppert K., Nalesnik M.A., Randhawa P., et al. Recurrent hepatitis C in liver allografts: prospective assessment of diagnostic accuracy, identification of pitfalls, and observations about pathogenesis. Am J Surg Pathol 28 (2004) 658-669
14. Ishak K., Baptista A., Bianchi L., Callea F., De Groote J., Gudat F., et al. Histological grading and staging of chronic hepatitis. J Hepatol 22 (1995) 696-699
15. No authors listed. Banff schema for grading liver allograft rejection: an international consensus document. Hepatology 1997;25:658-63.
16. Kronenberg M. Toward an understanding of NKT cell biology: progress and paradoxes. Annu Rev Immunol 23 (2005) 877-900
17. Murphy K., Travers P., and Walport M. Janeway's immunobiology. 7th ed. (2008), Garland Science, New York
18. dim NK cells upon activation. J Immunol 178 (2007) 4947-4955
19. dim cells: role of contact with peripheral fibroblasts. J Immunol 179 (2007) 89-94
20. Miyamoto M., Emoto M., Brinkmann V., Van Rooijen N., Schmits R., Kita E., et al. Cutting edge: contribution of NK cells to the homing of thymic CD4+NKT cells to the liver. J Immunol 165 (2000) 1729-1732
21. Vacher-Coponat H., Brunet C., Moal V., Loundou A., Bonnet E., Lyonnet L., et al. Tacrolimus/mycophenolate mofetil improved natural killer lymphocyte reconstitution one year after kidney transplant by reference to cyclosporine/azathioprine. Transplantation 82 (2006) 558-566
22. Gluhovschi C., Gluhovschi G., Herman D., Potencz E., Trandafirescu V., Schiller A., et al. The effects of steroids on lymphocyte profile in primary chronic glomerulonephritis empirical or tailored therapy?. Int Immunopharmacol 7 (2007) 1265-1270
23. Lanier L.L. NK cell recognition. Annu Rev Immunol 23 (2005) 225-274
24. Stewart C.A., Vivier E., and Colonna M. Strategies of natural killer cell recognition and signaling. Curr Top Microbiol Immunol 298 (2006) 1-21
25. Caligiuri M.A. Human natural killer cells. Blood 112 (2008) 461-469
26. Clausen J., Vergeiner B., Enk M., Petzer A.L., Gastl G., and Gunsilius E. Functional significance of the activation-associated receptors CD25 and CD69 on human NK-cells and NK-like T-cells. Immunobiology 207 (2003) 85-93
27. Oliviero B., Varchetta S., Cerino A., Paudice E., Michelone G., Zaramella M., et al. Enhanced NK cell cytolytic activity in chronic HCV infection. J Hepatol 48 (2008) S51
28. Raulet D.H. Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 3 (2003) 781-790
29. Burgess S.J., Maasho K., Madhan M., Narayanan S., Borrego F., and Coligan J.E. The NKG2D receptor: immunobiology and clinical implications. Immunol Res 40 (2008) 18-34
30. Bauer S., Groh V., Wu J., Steinle A., Phillips J.H., Lanier L.L., et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285 (1999) 727-729
31. Cosman D., Mullberg J., Sutherland C.L., Chin W., Armitage R., Fanslow W., et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14 (2001) 123-133
32. Mizutani K., Terasaki P., Bignon J.D., Hourmant M., Cesbron-Gautier A., Shih R.N., et al. Association of kidney transplant failure and antibodies against MICA. Hum Immunol 67 (2006) 683-691
33. Ogasawara K., Benjamin J., Takaki R., Phillips J.H., and Lanier L.L. Function of NKG2D in natural killer cell-mediated rejection of mouse bone marrow grafts. Nat Immunol 6 (2005) 938-945
34. Gumá M., Budt M., Saez A., Brckalo T., Hengel H., Angulo A., et al. Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts. Blood 107 (2006) 3624-3631
35. Mela C.M., Burton C.T., Imami M., Nelson M., Steel A., Gazzard B.G., et al. Switch from inhibitory to activating NKG2 receptor expression in HIV-1 infection: lack of reversion with highly active antiretroviral therapy. AIDS 19 (2005) 1761-1769
36. Fausther-Bovendo H., Wauquier N., Cherfils-Vicini J., Cremer I., Debre P., and Vieillard V. NKG2C is a major triggering receptor involved in the V[delta]1 T cell-mediated cytotoxicity against HIV-infected CD4 T cells. AIDS 22 (2008) 217-226
37. Fogli M., Mavilio D., Brunetta E., Varchetta S., Ata K., Roby G., et al. Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals. PLoS Pathog 4 (2008) e1000101