Propofol pretreatment reduces ceramide production and attenuates intestinal mucosal apoptosis induced by intestinal ischemia/reperfusion in rats

Anesthesia and Analgesia

Volumn 107, Issue 6, 2008, Pages 1884-1891

  Liu, Ke Xuan ^a   Chen, Shu Qing ^a   Huang, Wen Qi ^a   Li, Yun Sheng ^a   Irwin, Michael G ^b   Xia, Zhengyuan ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; MALONALDEHYDE; MESSENGER RNA; PROPOFOL; SPHINGOMYELIN PHOSPHODIESTERASE; SUPEROXIDE DISMUTASE; INTRAVENOUS ANESTHETIC AGENT;

ANESTHESIA; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTERY CLAMP; ARTICLE; COLORIMETRY; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; ELECTRON MICROSCOPY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ISCHEMIA; INTESTINE MUCOSA; LIPID OXIDATION; LIPOGENESIS; MALE; NICK END LABELING; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN INCISION; STIMULUS; SUPERIOR MESENTERIC ARTERY; UPREGULATION; ANIMAL; BIOSYNTHESIS; GENETICS; METABOLISM; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WISTAR RAT;

ANESTHETICS, INTRAVENOUS; ANIMALS; APOPTOSIS; CERAMIDES; INTESTINAL MUCOSA; MALE; MALONDIALDEHYDE; MICROSCOPY, ELECTRON, TRANSMISSION; PROPOFOL; RATS; RATS, WISTAR; REPERFUSION INJURY; RNA, MESSENGER; SPHINGOMYELIN PHOSPHODIESTERASE; SUPEROXIDE DISMUTASE;

EID: 58149295458     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e3181884bbf     Document Type: Article

References (36)

1. Homer-Vanniasinkam S, Crinnion JN, Gough MJ. Postischaemic organ dysfunction: a review. Eur J Vasc Endovasc Surg 1997;14:195-203
2. Deitch EA. Role of the gut in multiple system organ failure. Curr Opin Crit Care 2001;7:92-8
3. Mitsuoka H, Kistler EB, Schmid-Schonbein GW. Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock. Shock 2002;17:205-9
4. Ikeda H, Suzuki Y, Suzuki M, Koike M, Tamura J, Tong J, Nomura M, Itoh G. Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium. Gut 1998;42:530-7
5. Sun Z, Wang X, Deng X, Lasson A, Walle'n R, Hallberg E, Andersson R. The influence of intestinal ischemia and reperfusion on bidirectional intestinal barrier permeability, cellular membrane integrity, proteinase inhibitors, and cell death in rats. Shock 1998;10:203-12
6. Noda T, Iwakiri R, Fujimoto K, Matsuo S, Aw TY. Programmed cell death induced by ischemia-reperfusion in rat intestinal mucosa. Am J Physiol 1998;274(2 Pt 1):G270-G276
7. Kuenzler KA, Pearson PY, Schwartz MZ. IL-11 pretreatment reduces cell death after intestinal ischemia-reperfusion. J Surg Res 2002;108:268-72
8. HannunYA. Functions of ceramide in coordinating cellular responses to stress. Science 1996;274:1855-9
9. Liu KX, He W, Rinne T, Liu Y, Zhao MQ, Wu WK. The effect of Ginkgo biloba extract (EGb 761) pretreatment on intestinal epithelial apoptosis induced by intestinal ischemia/reperfusion in rats: role of ceramide. Am J Chin Med 2007;35:805-19
10. Ogretmen B, Hannun Y A. Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer 2004; 4:604-6
11. Kolesnick R. The therapeutic potential of modulating the ceramide/sphingomyelin pathway. J Clin Invest 2002;110:3-8
12. Merrill AH Jr, Schmelz EM, Dillehay DL, Spiegel S, Shayman JA, Schroeder JJ, Riley RT, Voss KA, Wang E. Sphingolipids-the enigmatic lipid class: biochemistry, physiology, and pathophysiology. Toxico Appl Pharmacol 1997;142:208-25
13. Murphy PG, Myers DS, Davies MJ, Webster NR, Jones JG. The antioxidant potential of propofol (2,6-diisopropylphenol). Br J Anaesth 1992;68:613-8
14. Thiry JC, Hans P, Deby-Dupont G, Mouythis-Mickalad A, Bonhomme V, Lamy M. Propofol scavenges reactive oxygen species and inhibits the protein nitration induced by activated polymorphonuclear neutrophils. Eur J Pharmacol 2004;499:29-33
15. Xia Z, Huang Z, Ansley DM. Large-dose propofol during cardiopulmonary bypass decreases biochemical markers of myocardial injury in coronary surgery patients: a comparison with isoflurane. Anesth Analg 2006;103:527-32
16. De Hert SG, Cromheecke S, ten Broecke PW, Mertens E, De Blier IG, Stockman BA, Rodrigus IE, Van der Linden PJ. Effects of propofol, desflurane, and sevoflurane on recovery of myocardial function after coronary surgery in elderly high-risk patients. Anesthesiology 2003;99:314-23
17. Bovill JG. Intravenous anesthesia for the patient with left ventricular dysfunction. Semin Cardiothorac Vasc Anesth 2006;10:43-8
18. Liu KX, Rinne T, He W, Wang F, Xia Z. Propofol pretreatment attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in the rats. Can J Anaesth 2007;54:366-74
19. Inagawa G, Sato K, Kikuchi T, Nishihama M, Shioda M, Koyama Y, Yamada Y, Andoh T. Chronic ethanol consumption does not affect action of propofol on rat hippocampal acetylcholine release in vivo. Br J Anaesth 2004;93:37-9
20. Brasil LJ, San-Miguel B, Kretzmann NA, Amaral JL, Zettler CG, Marroni N, Gonza'lez-Gallego J, Tuño'n MJ. Halothane induces oxidative stress and NF-kappaB activation in rat liver: protective effect of propofol. Toxicology 2006;227:53-61
21. Liu KX, Wu WK, Liu CL, He W. Ginkgo biloba extract (EGb 761) attenuates lung injury induced by intestinal ischemia/reperfusion in rats: Roles of oxidative stress and nitric oxide. World J Gastroenterol 2007;13:299-305
22. Dasgupta S, Hogan EL. Chromatographic resolution and quantitative assay of CNS tissue sphingoids and sphingolipids. J Lipid Res 2001;42:301-8
23. Sultan I, Senkal CE, Ponnusamy S, Bielawski J, Szulc Z, Bielawska A, Hannun YA, Ogretmen B. Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function. J Biol Chem 2006;393(Pt 2):513-21
24. Won JS, Singh I. Sphingolipid signaling and redox regulation. Free Radic Biol Med 2006;40:1875-88
25. Hertervig E, Nilsson A, Nyberg L, Duan RD. Alkaline sphingomyelinase activity is decreased in human colorectal carcinoma. Cancer 1996;79:448-53
26. Lavrentiadou SN, Chan C, Kawcak T, Ravid T, Tsaba A, van der Vliet A, Rasooly R, Goldkorn T. Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. Am J Respir Cell Mol Bio 2001;25:676-84
27. Liu B, Andrieu-Abadie N, Levade T, Zhang P, Obeid LM, Hannun YA. Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-induced cell death. J Biol Chem 1998;273:11313-20
28. Hertervig E, Nilsson A, Cheng Y, Duan RD. Purified intestinal alkaline sphingomyelinase inhibits proliferation without inducing apoptosis in HT-29 colon carcinoma cells. J Cancer Res Clin Oncol 2003;129:577-82
29. Duan RD, Cheng Y, Hansen G, Hertervig E, Liu JJ, Syk I, Sjostrom H, Nilsson A. Purification, localization, and expression of human intestinal alkaline sphingomyelinase. J Lipid Res 2003;44:1241-50
30. Matsunaga T, Kotamraju S, Kalivendi SV, Dhanasekaran A, Joseph J, Kalyanaraman B. Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: protective role of endogenous nitric oxide. J Biol Chem 2004;279:28614-24
31. Zhu B, Ye TH, Zhao JX. Protective effect of propofol at clinically relevant concentrations on primary cultured newborn rat hippocampus. Chin Med J 2005;118:603-5
32. Carrizo GJ, Wu R, Cui X, Dwivedi AJ, Simms HH, Wang P. Adrenomedullin and adrenomedullin-binding protein-1 downregulate inflammatory cytokines and attenuate tissue injury after gut ischemia-reperfusion. Surgery 2007;141:245-53
33. Taniguchi T, Yamamoto K, Ohmoto N, Ohta K, Kobayashi T. Effects of propofol on hemodynamic and inflammatory responses to endotoxemia in rats. Crit Care Med 2000;28:1101-6
34. Taniguchi T, Kanakura H, Yamamoto K. Effects of posttreatment with propofol on mortality and cytokine responses to endotoxin-induced shock in rats. Crit Care Med 2002;30:904-7
35. Takemoto Y. Dose effects of propofol on hemodynamic and cytokine responses to endotoxemia in rats. J Anesth 2005; 19:40-4
36. Takaono M, Yogosawa T, Okawa-Takatsuji M, Aotsuka S. Effects of intravenous anesthetics on interleukin (IL)-6 and IL-10 production by lipopolysaccharide-stimulated mononuclear cells from healthy volunteers. Acta Anaesthesiol Scand 2002;46:176 -9