-
1
-
-
0021149603
-
The development of human benign prostatic hyperplasia with age
-
Berry SJ, Coffey DS, Walsh PC, Ewing LL: The development of human benign prostatic hyperplasia with age. J Urol 1984, 132:474-479.
-
(1984)
J Urol
, vol.132
, pp. 474-479
-
-
Berry, S.J.1
Coffey, D.S.2
Walsh, P.C.3
Ewing, L.L.4
-
2
-
-
0037940268
-
Comparison of lower urinary tract symptom severity and associated bother between community-dwelling black and white men: The Olmsted County Study of Urinary Symptoms and Health Status and the Flint Men's Health Study
-
Sarma AV, Wei JT, Jacobson DJ, et al.: Comparison of lower urinary tract symptom severity and associated bother between community-dwelling black and white men: the Olmsted County Study of Urinary Symptoms and Health Status and the Flint Men's Health Study. Urology 2003, 61:1086-1091.
-
(2003)
Urology
, vol.61
, pp. 1086-1091
-
-
Sarma, A.V.1
Wei, J.T.2
Jacobson, D.J.3
-
3
-
-
15044344536
-
Urologic diseases in America project: Benign prostatic hyperplasia
-
Wei JT, Calhoun E, Jacobsen SJ: Urologic diseases in America project: benign prostatic hyperplasia. J Urol 2005, 173:1256-1261.
-
(2005)
J Urol
, vol.173
, pp. 1256-1261
-
-
Wei, J.T.1
Calhoun, E.2
Jacobsen, S.J.3
-
4
-
-
0028942322
-
New diagnostic and treatment guidelines for benign prostatic hyperplasia. Potential impact in the United States
-
Jacobsen SJ, Girman CJ, Guess HA, et al.: New diagnostic and treatment guidelines for benign prostatic hyperplasia. Potential impact in the United States. Arch Intern Med 1995, 155:477-481.
-
(1995)
Arch Intern Med
, vol.155
, pp. 477-481
-
-
Jacobsen, S.J.1
Girman, C.J.2
Guess, H.A.3
-
5
-
-
0018765076
-
Patterns of inflammation in prostatic hyperplasia: A histologic and bacteriologic study
-
Kohnen PW, Drach GW: Patterns of inflammation in prostatic hyperplasia: a histologic and bacteriologic study. J Urol 1979, 121:755-760.
-
(1979)
J Urol
, vol.121
, pp. 755-760
-
-
Kohnen, P.W.1
Drach, G.W.2
-
6
-
-
0037326098
-
Distribution of inflammation, pre-malignant lesions, incidental carcinoma in histologically confirmed benign prostatic hyperplasia: A retrospective analysis
-
Di Silverio F, Gentile V, De Matteis A, et al.: Distribution of inflammation, pre-malignant lesions, incidental carcinoma in histologically confirmed benign prostatic hyperplasia: a retrospective analysis. Eur Urol 2003, 43:164-175.
-
(2003)
Eur Urol
, vol.43
, pp. 164-175
-
-
Di Silverio, F.1
Gentile, V.2
De Matteis, A.3
-
7
-
-
0036223581
-
Distribution of chronic prostatitis in radical prostatectomy specimens with up-regulation of bcl-2 in areas of inflammation
-
Gerstenbluth RE, Seftel AD, MacLennan GT, et al.: Distribution of chronic prostatitis in radical prostatectomy specimens with up-regulation of bcl-2 in areas of inflammation. J Urol 2002, 167:2267-2270.
-
(2002)
J Urol
, vol.167
, pp. 2267-2270
-
-
Gerstenbluth, R.E.1
Seftel, A.D.2
MacLennan, G.T.3
-
8
-
-
33644523454
-
Relationship between serum prostate specific antigen and the pattern of inflammation in both benign and malignant prostatic disease in Middle Eastern men
-
Anim JT, Kehinde EO, Prasad A, et al.: Relationship between serum prostate specific antigen and the pattern of inflammation in both benign and malignant prostatic disease in Middle Eastern men. Int Urol Nephrol 2006, 38:27-32.
-
(2006)
Int Urol Nephrol
, vol.38
, pp. 27-32
-
-
Anim, J.T.1
Kehinde, E.O.2
Prasad, A.3
-
9
-
-
58149288152
-
-
•• Roehrborn C, Kaplan SA, Noble WD, et al.: The impact of acute or chronic inflammation in baseline biopsy on the risk of clinical progression of BPH: results of the MTOP study [abstract]. J Urol 2005, 173:204. This provocative abstract provides important data describing a temporal relationship between the presence of prostatic inflammation and the development of adverse urologic outcomes.
-
•• Roehrborn C, Kaplan SA, Noble WD, et al.: The impact of acute or chronic inflammation in baseline biopsy on the risk of clinical progression of BPH: results of the MTOP study [abstract]. J Urol 2005, 173:204. This provocative abstract provides important data describing a temporal relationship between the presence of prostatic inflammation and the development of adverse urologic outcomes.
-
-
-
-
10
-
-
10144246588
-
-
•• Rohrmann S, De Marzo AM, Smit E, et al.: Serum C-reactive protein concentration and lower urinary tract symptoms in older men in the Third National Health and Nutrition Examination Survey (NHANES III). Prostate 2005, 62:27-33. This is the only currently available study to examine the association between a nonprostatic measure of inflammation and LUTS.
-
•• Rohrmann S, De Marzo AM, Smit E, et al.: Serum C-reactive protein concentration and lower urinary tract symptoms in older men in the Third National Health and Nutrition Examination Survey (NHANES III). Prostate 2005, 62:27-33. This is the only currently available study to examine the association between a nonprostatic measure of inflammation and LUTS.
-
-
-
-
11
-
-
34547677616
-
-
• Nickel JC, Roehrborn CG, O'Leary MP, et al.: Examination of the relationship between symptoms of prostatitis and histological inflammation: baseline data from the REDUCE chemoprevention trial. J Urol 2007, 178:896-900; discussion 900-891. This study found small, nonclinically significant associations between the presence of prostatic inflammation and symptoms of prostatitis, including presence of urinary symptoms.
-
• Nickel JC, Roehrborn CG, O'Leary MP, et al.: Examination of the relationship between symptoms of prostatitis and histological inflammation: baseline data from the REDUCE chemoprevention trial. J Urol 2007, 178:896-900; discussion 900-891. This study found small, nonclinically significant associations between the presence of prostatic inflammation and symptoms of prostatitis, including presence of urinary symptoms.
-
-
-
-
12
-
-
0027172773
-
Relationship between prostate specific antigen, prostate volume and age in the benign prostate
-
Collins GN, Lee RJ, McKelvie GB, et al.: Relationship between prostate specific antigen, prostate volume and age in the benign prostate. Br J Urol 1993, 71:445-450.
-
(1993)
Br J Urol
, vol.71
, pp. 445-450
-
-
Collins, G.N.1
Lee, R.J.2
McKelvie, G.B.3
-
13
-
-
32044437826
-
Tracking of longitudinal changes in measures of benign prostatic hyperplasia in a population based cohort
-
discussion 1022
-
St Sauver JL, Jacobson DJ, Girman CJ, et al.: Tracking of longitudinal changes in measures of benign prostatic hyperplasia in a population based cohort. J Urol 2006, 175:1018-1022; discussion 1022.
-
(2006)
J Urol
, vol.175
, pp. 1018-1022
-
-
St Sauver, J.L.1
Jacobson, D.J.2
Girman, C.J.3
-
14
-
-
21844464091
-
-
• Tuncel A, Uzun B, Eruyar T, et al.: Do prostatic infarction, prostatic inflammation and prostate morphology play a role in acute urinary retention? Eur Urol 2005, 48:277-283; discussion 283-274. This case-controlled study found an association between presence of prostatic inflammation and AUR independent of prostate
-
• Tuncel A, Uzun B, Eruyar T, et al.: Do prostatic infarction, prostatic inflammation and prostate morphology play a role in acute urinary retention? Eur Urol 2005, 48:277-283; discussion 283-274. This case-controlled study found an association between presence of prostatic inflammation and AUR independent of prostate volume.
-
-
-
-
15
-
-
33646239640
-
-
• Kefi A, Koseoglu H, Celebi I, et al.: Relation between acute urinary retention, chronic prostatic inflammation and accompanying elevated prostate-specific antigen. Scand J Urol Nephrol 2006, 40:155-160. Together with Tuncel et al [14•], this case-controlled study also found an association, independent of prostate between presence of prostatic inflammation and AUR.
-
• Kefi A, Koseoglu H, Celebi I, et al.: Relation between acute urinary retention, chronic prostatic inflammation and accompanying elevated prostate-specific antigen. Scand J Urol Nephrol 2006, 40:155-160. Together with Tuncel et al [14•], this case-controlled study also found an association, independent of prostate volume, between presence of prostatic inflammation and AUR.
-
-
-
-
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-
-
34447129024
-
-
• Mishra VC, Allen DJ, Nicolaou C, et al.: Does intraprostatic inflammation have a role in the pathogenesis and progression of benign prostatic hyperplasia? BJU Int 2007, 100:327-331. These data add to the results of Tuncel et al. [14•] and Kefi et al. [15•] in establishing a role for prostatic inflammation in AUR.
-
• Mishra VC, Allen DJ, Nicolaou C, et al.: Does intraprostatic inflammation have a role in the pathogenesis and progression of benign prostatic hyperplasia? BJU Int 2007, 100:327-331. These data add to the results of Tuncel et al. [14•] and Kefi et al. [15•] in establishing a role for prostatic inflammation in AUR.
-
-
-
-
17
-
-
0031906466
-
Role of chronic inflammation in the promotion of prostatic hyperplasia in rats
-
Kessler OJ, Keisari Y, Servadio C, Abramovici A: Role of chronic inflammation in the promotion of prostatic hyperplasia in rats. J Urol 1998, 159:1049-1053.
-
(1998)
J Urol
, vol.159
, pp. 1049-1053
-
-
Kessler, O.J.1
Keisari, Y.2
Servadio, C.3
Abramovici, A.4
-
18
-
-
0027982930
-
Phenotype and function of peripheral and prostatic lymphocytes in patients with benign prostatic hyperplasia
-
Steiner G, Gessl A, Kramer G, et al.: Phenotype and function of peripheral and prostatic lymphocytes in patients with benign prostatic hyperplasia. J Urol 1994, 151:480-484.
-
(1994)
J Urol
, vol.151
, pp. 480-484
-
-
Steiner, G.1
Gessl, A.2
Kramer, G.3
-
19
-
-
0038753780
-
Intraepithelial and stromal lymphocytes in the normal human prostate
-
Bostwick DG, de la Roza G, Dundore P, et al.: Intraepithelial and stromal lymphocytes in the normal human prostate. Prostate 2003, 55:187-193.
-
(2003)
Prostate
, vol.55
, pp. 187-193
-
-
Bostwick, D.G.1
de la Roza, G.2
Dundore, P.3
-
20
-
-
0031757612
-
Characterisation of inflammatory cells in benign prostatic hyperplasia
-
Anim JT, Udo C, John B: Characterisation of inflammatory cells in benign prostatic hyperplasia. Acta Histochem 1998, 100:439-449.
-
(1998)
Acta Histochem
, vol.100
, pp. 439-449
-
-
Anim, J.T.1
Udo, C.2
John, B.3
-
21
-
-
33947247395
-
Kramer G, Mitteregger D, Marberger M: Is benign prostatic hyperplasia (BPH) an immune inflammatory disease?
-
••, This interesting review article proposes that BPH meets several characteristic criteria for immune inflammatory diseases
-
•• Kramer G, Mitteregger D, Marberger M: Is benign prostatic hyperplasia (BPH) an immune inflammatory disease? Eur Urol 2007, 51:1202-1216. This interesting review article proposes that BPH meets several characteristic criteria for immune inflammatory diseases.
-
(2007)
Eur Urol
, vol.51
, pp. 1202-1216
-
-
-
22
-
-
0035209077
-
Differential expression of interleukin-15, a pro-inflammatory cytokine and T-cell growth factor, and its receptor in human prostate
-
Handisurya A, Steiner GE, Stix U, et al.: Differential expression of interleukin-15, a pro-inflammatory cytokine and T-cell growth factor, and its receptor in human prostate. Prostate 2001, 49:251-262.
-
(2001)
Prostate
, vol.49
, pp. 251-262
-
-
Handisurya, A.1
Steiner, G.E.2
Stix, U.3
-
23
-
-
2442443317
-
Down-regulation of macrophage inhibitory cytokine-1/prostate derived factor in benign prostatic hyperplasia
-
Kakehi Y, Segawa T, Wu XX, et al.: Down-regulation of macrophage inhibitory cytokine-1/prostate derived factor in benign prostatic hyperplasia. Prostate 2004, 59:351-356.
-
(2004)
Prostate
, vol.59
, pp. 351-356
-
-
Kakehi, Y.1
Segawa, T.2
Wu, X.X.3
-
24
-
-
2442608523
-
Association of prostatic inflammation with down-regulation of macrophage inhibitory cytokine-1 gene in symptomatic benign prostatic hyperplasia
-
Taoka R, Tsukuda F, Ishikawa M, et al.: Association of prostatic inflammation with down-regulation of macrophage inhibitory cytokine-1 gene in symptomatic benign prostatic hyperplasia. J Urol 2004, 171:2330-2335.
-
(2004)
J Urol
, vol.171
, pp. 2330-2335
-
-
Taoka, R.1
Tsukuda, F.2
Ishikawa, M.3
-
25
-
-
0041669594
-
Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate
-
Steiner GE, Newman ME, Paikl D, et al.: Expression and function of pro-inflammatory interleukin IL-17 and IL-17 receptor in normal, benign hyperplastic, and malignant prostate. Prostate 2003, 56:171-182.
-
(2003)
Prostate
, vol.56
, pp. 171-182
-
-
Steiner, G.E.1
Newman, M.E.2
Paikl, D.3
-
26
-
-
33845570300
-
-
• Penna G, Mondaini N, Amuchastegui S, et al.: Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis/ chronic pelvic pain syndrome and benign prostatic hyperplasia. Eur Urol 2007, 51:524-533; discussion 533. This manuscript attempts to bridge basic science and clinical data, by both noting an increased level of IL-8 in BPH patients and an association between IL-8 level and urinary symptoms.
-
• Penna G, Mondaini N, Amuchastegui S, et al.: Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis/ chronic pelvic pain syndrome and benign prostatic hyperplasia. Eur Urol 2007, 51:524-533; discussion 533. This manuscript attempts to bridge basic science and clinical data, by both noting an increased level of IL-8 in BPH patients and an association between IL-8 level and urinary symptoms.
-
-
-
-
27
-
-
0346656567
-
Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplasic, and malignant human prostate
-
Royuela M, Ricote M, Parsons MS, et al.: Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplasic, and malignant human prostate. J Pathol 2004, 202:41-49.
-
(2004)
J Pathol
, vol.202
, pp. 41-49
-
-
Royuela, M.1
Ricote, M.2
Parsons, M.S.3
-
28
-
-
0036604284
-
Increased expression of lymphocyte-derived cytokines in benign hyperplastic prostate tissue, identification of the producing cell types, and effect of differentially expressed cytokines on stromal cell proliferation
-
Kramer G, Steiner GE, Handisurya A, et al.: Increased expression of lymphocyte-derived cytokines in benign hyperplastic prostate tissue, identification of the producing cell types, and effect of differentially expressed cytokines on stromal cell proliferation. Prostate 2002, 52:43-58.
-
(2002)
Prostate
, vol.52
, pp. 43-58
-
-
Kramer, G.1
Steiner, G.E.2
Handisurya, A.3
-
29
-
-
0042178346
-
Cytokine expression pattern in benign prostatic hyperplasia infiltrating T cells and impact of lymphocytic infiltration on cytokine mRNA profile in prostatic tissue
-
Steiner GE, Stix U, Handisurya A, et al.: Cytokine expression pattern in benign prostatic hyperplasia infiltrating T cells and impact of lymphocytic infiltration on cytokine mRNA profile in prostatic tissue. Lab Invest 2003, 83, 1131-1146.
-
(2003)
Lab Invest
, vol.83
, pp. 1131-1146
-
-
Steiner, G.E.1
Stix, U.2
Handisurya, A.3
-
30
-
-
0035404541
-
Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia
-
Giri D, Ittmann M: Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia. Am J Pathol 2001, 159:139-147.
-
(2001)
Am J Pathol
, vol.159
, pp. 139-147
-
-
Giri, D.1
Ittmann, M.2
-
31
-
-
2942584846
-
Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia
-
Castro P, Xia C, Gomez L, et al.: Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia. Prostate 2004, 60:153-159.
-
(2004)
Prostate
, vol.60
, pp. 153-159
-
-
Castro, P.1
Xia, C.2
Gomez, L.3
-
32
-
-
0038035216
-
T-cell-derived interleukin-17 regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of the p38 mitogen-activated protein kinase cascade: Role of distal sequences in the 3′-untranslated region of COX-2 mRNA
-
Faour WH, Mancini A, He QW, Di Battista JA: T-cell-derived interleukin-17 regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of the p38 mitogen-activated protein kinase cascade: role of distal sequences in the 3′-untranslated region of COX-2 mRNA. J Biol Chem 2003, 278:26897-26907.
-
(2003)
J Biol Chem
, vol.278
, pp. 26897-26907
-
-
Faour, W.H.1
Mancini, A.2
He, Q.W.3
Di Battista, J.A.4
-
33
-
-
4143109119
-
Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium
-
Wang W, Bergh A, Damber JE: Chronic inflammation in benign prostate hyperplasia is associated with focal upregulation of cyclooxygenase-2, Bcl-2, and cell proliferation in the glandular epithelium. Prostate 2004, 61:60-72.
-
(2004)
Prostate
, vol.61
, pp. 60-72
-
-
Wang, W.1
Bergh, A.2
Damber, J.E.3
-
34
-
-
84869982092
-
-
•• Lin VK, Wang SY, Roehrborn C: Alpha adrenergic stimulation regulates cox-2 expression in prostate stroma cells (abstract). J Urol 2005, 173 (Suppl):390. This interesting abstract has not been published in manuscript form, but suggests a fascinating association between upregulation of the α-adrenergic pathway and COX-2.
-
•• Lin VK, Wang SY, Roehrborn C: Alpha adrenergic stimulation regulates cox-2 expression in prostate stroma cells (abstract). J Urol 2005, 173 (Suppl):390. This interesting abstract has not been published in manuscript form, but suggests a fascinating association between upregulation of the α-adrenergic pathway and COX-2.
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-
-
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-
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0029899625
-
Apoptotic versus proliferative activities in human benign prostatic hyperplasia
-
Kyprianou N, Tu H, Jacobs SC: Apoptotic versus proliferative activities in human benign prostatic hyperplasia. Hum Pathol 1996, 27:668-675.
-
(1996)
Hum Pathol
, vol.27
, pp. 668-675
-
-
Kyprianou, N.1
Tu, H.2
Jacobs, S.C.3
-
36
-
-
27544438131
-
-
• Shariat SF, Ashfaq R, Roehrborn CG, et al.: Expression of survivin and apoptotic biomarkers in benign prostatic hyperplasia. J Urol 2005, 174:2046-2050. This paper begins to explore the role of apoptotic biomarkers in BPH beyond BCL-2.
-
• Shariat SF, Ashfaq R, Roehrborn CG, et al.: Expression of survivin and apoptotic biomarkers in benign prostatic hyperplasia. J Urol 2005, 174:2046-2050. This paper begins to explore the role of apoptotic biomarkers in BPH beyond BCL-2.
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-
-
-
37
-
-
0030021726
-
Evidence for atrophy and apoptosis in the prostates of men given finasteride
-
Rittmaster RS, Norman RW, Thomas LN, Rowden G: Evidence for atrophy and apoptosis in the prostates of men given finasteride. J Clin Endocrinol Metab 1996, 81:814-819.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 814-819
-
-
Rittmaster, R.S.1
Norman, R.W.2
Thomas, L.N.3
Rowden, G.4
-
38
-
-
0036617272
-
Induction of apoptosis in rat ventral prostate by finasteride is associated with alteration in MAP kinase pathways and Bcl-2 related family of proteins
-
Huynh H: Induction of apoptosis in rat ventral prostate by finasteride is associated with alteration in MAP kinase pathways and Bcl-2 related family of proteins. Int J Oncol 2002, 20:1297-1303.
-
(2002)
Int J Oncol
, vol.20
, pp. 1297-1303
-
-
Huynh, H.1
-
39
-
-
1642417428
-
Apoptotic impact of alpha1-blockers on prostate cancer growth: A myth or an inviting reality?
-
Tahmatzopoulos A, Kyprianou N: Apoptotic impact of alpha1-blockers on prostate cancer growth: a myth or an inviting reality? Prostate 2004, 59:91-100.
-
(2004)
Prostate
, vol.59
, pp. 91-100
-
-
Tahmatzopoulos, A.1
Kyprianou, N.2
-
40
-
-
31544446659
-
Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway
-
Garrison JB, Kyprianou N: Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res 2006, 66:464-472.
-
(2006)
Cancer Res
, vol.66
, pp. 464-472
-
-
Garrison, J.B.1
Kyprianou, N.2
-
41
-
-
33745663261
-
-
• Roehrborn CG: Three months' treatment with the alpha1-blocker alfuzosin does not affect total or transition zone of the prostate. Prostate Cancer Prostatic Dis 2006, 9:121-125. This study did not find a clinical association between the potential apoptotic effects of alfuzosin and decreased prostate however, 3 months' treatment may not have been long enough to observe any clinical changes in prostate
-
• Roehrborn CG: Three months' treatment with the alpha1-blocker alfuzosin does not affect total or transition zone volume of the prostate. Prostate Cancer Prostatic Dis 2006, 9:121-125. This study did not find a clinical association between the potential apoptotic effects of alfuzosin and decreased prostate volume; however, 3 months' treatment may not have been long enough to observe any clinical changes in prostate volume.
-
-
-
-
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-
-
33749460341
-
-
•• St. Sauver JL, Jacobson D, McGree ME, et al.: Protective association between non-steroidal anti-inflammatory drug use and measures of benign prostatic hyperplasia. Am J Epidemiol 2006, 164:760-768. This paper examines the association between NSAID use and urologic outcomes, finding a protective association between daily use of NSAID and prostate LUTS, and AUR, suggesting that NSAIDs may be useful in preventing some of these conditions.
-
•• St. Sauver JL, Jacobson D, McGree ME, et al.: Protective association between non-steroidal anti-inflammatory drug use and measures of benign prostatic hyperplasia. Am J Epidemiol 2006, 164:760-768. This paper examines the association between NSAID use and urologic outcomes, finding a protective association between daily use of NSAID and prostate volume, LUTS, and AUR, suggesting that NSAIDs may be useful in preventing some of these conditions.
-
-
-
-
43
-
-
20444445530
-
-
• Minnery CH, Getzenberg RH: Benign prostatic hyperplasia cell line viability and modulation of jm-27 by doxazosin and Ibuprofen. J Urol 2005, 174:375-379. These authors provide basic science data to suggest that both doxazosin and ibuprofen act through JM-27 to reduce prostate growth via increased cell death and increased apoptosis.
-
• Minnery CH, Getzenberg RH: Benign prostatic hyperplasia cell line viability and modulation of jm-27 by doxazosin and Ibuprofen. J Urol 2005, 174:375-379. These authors provide basic science data to suggest that both doxazosin and ibuprofen act through JM-27 to reduce prostate growth via increased cell death and increased apoptosis.
-
-
-
-
44
-
-
0142259751
-
BPH and inflammation: Pharmacological effects of Permixon on histological and molecular inflammatory markers. Results of a double blind pilot clinical assay
-
Vela Navarrete R, Garcia Cardoso JV, Barat A, et al.: BPH and inflammation: pharmacological effects of Permixon on histological and molecular inflammatory markers. Results of a double blind pilot clinical assay. Eur Urol 2003, 44:549-555.
-
(2003)
Eur Urol
, vol.44
, pp. 549-555
-
-
Vela Navarrete, R.1
Garcia Cardoso, J.V.2
Barat, A.3
-
45
-
-
0021139797
-
Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of rat urinary bladder
-
Maggi CA, Evangelista S, Grimaldi G, et al.: Evidence for the involvement of arachidonic acid metabolites in spontaneous and drug-induced contractions of rat urinary bladder. J Pharmacol Exp Ther 1984, 230:500-513.
-
(1984)
J Pharmacol Exp Ther
, vol.230
, pp. 500-513
-
-
Maggi, C.A.1
Evangelista, S.2
Grimaldi, G.3
-
46
-
-
0031809295
-
Pharmacological characterization of thromboxane and prostanoid receptors in human isolated urinary bladder
-
Palea S, Toson G, Pietra C, et al.: Pharmacological characterization of thromboxane and prostanoid receptors in human isolated urinary bladder. Br J Pharmacol 1998, 124:865-872.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 865-872
-
-
Palea, S.1
Toson, G.2
Pietra, C.3
-
47
-
-
0032890990
-
Obstruction stimulates COX-2 expression in bladder smooth muscle cells via increased mechanical stretch
-
Park JM, Yang T, Arend LJ, et al.: Obstruction stimulates COX-2 expression in bladder smooth muscle cells via increased mechanical stretch. Am J Physiol 1999, 276: F129-136.
-
(1999)
Am J Physiol
, vol.276
-
-
Park, J.M.1
Yang, T.2
Arend, L.J.3
-
48
-
-
0346848806
-
Monocyte chemoattractant protein-1 production by human detrusor smooth muscle cells
-
Bouchelouche K, Alvarez S, Andersen L, et al.: Monocyte chemoattractant protein-1 production by human detrusor smooth muscle cells. J Urol 2004, 171:462-466.
-
(2004)
J Urol
, vol.171
, pp. 462-466
-
-
Bouchelouche, K.1
Alvarez, S.2
Andersen, L.3
-
49
-
-
30344459452
-
-
• Bouchelouche K, Alvarez S, Horn T, et al.: Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha. Urology 2006, 67:214-219. This study provides basic science data indicating that detrusor smooth muscle cells are able to release proinflammatory cytokines.
-
• Bouchelouche K, Alvarez S, Horn T, et al.: Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha. Urology 2006, 67:214-219. This study provides basic science data indicating that detrusor smooth muscle cells are able to release proinflammatory cytokines.
-
-
-
-
50
-
-
4544388555
-
Effects of NSAIDs on bladder function in normal and cystitis rats: A comparison study of aspirin, indomethacin, and ketoprofen
-
Takagi-Matsumoto H, Ng B, Tsukimi Y, Tajimi M: Effects of NSAIDs on bladder function in normal and cystitis rats: a comparison study of aspirin, indomethacin, and ketoprofen. J Pharmacol Sci 2004, 95:458-465.
-
(2004)
J Pharmacol Sci
, vol.95
, pp. 458-465
-
-
Takagi-Matsumoto, H.1
Ng, B.2
Tsukimi, Y.3
Tajimi, M.4
-
51
-
-
33644917137
-
-
• Angelico P, Guarneri L, Velasco C, et al.: Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes. BJU Int 2006, 97:837-846. This study provides animal model data to suggest that efficacy of COX inhibitors in treating rat micturition conditions is related primarily to action on the COX-2 enzyme.
-
• Angelico P, Guarneri L, Velasco C, et al.: Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes. BJU Int 2006, 97:837-846. This study provides animal model data to suggest that efficacy of COX inhibitors in treating rat micturition conditions is related primarily to action on the COX-2 enzyme.
-
-
-
-
52
-
-
14644410481
-
The restorative effect of a selective cyclooxygenase-2 inhibitor on urothelial cell-cell interactions after partial bladder outlet obstruction in rats
-
Erdogru T, Celik-Ozenci C, Seval Y, et al.: The restorative effect of a selective cyclooxygenase-2 inhibitor on urothelial cell-cell interactions after partial bladder outlet obstruction in rats. BJU Int 2005, 95:664-669.
-
(2005)
BJU Int
, vol.95
, pp. 664-669
-
-
Erdogru, T.1
Celik-Ozenci, C.2
Seval, Y.3
-
53
-
-
0032454709
-
Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists
-
Meini S, Lecci A, Cucchi P, et al.: Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists. J Pharmacol Exp Ther 1998, 287:137-143.
-
(1998)
J Pharmacol Exp Ther
, vol.287
, pp. 137-143
-
-
Meini, S.1
Lecci, A.2
Cucchi, P.3
-
54
-
-
0018831582
-
A comparison between bromocriptine and indomethacin in the treatment of detrusor instability
-
Cardozo LD, Stanton SL: A comparison between bromocriptine and indomethacin in the treatment of detrusor instability. J Urol 1980, 123:399-401.
-
(1980)
J Urol
, vol.123
, pp. 399-401
-
-
Cardozo, L.D.1
Stanton, S.L.2
-
55
-
-
0018922153
-
Evaluation of flurbiprofen in detrusor instability
-
Cardozo LD, Stanton SL, Robinson H, Hole D: Evaluation of flurbiprofen in detrusor instability. Br Med J 1980, 280:281-282.
-
(1980)
Br Med J
, vol.280
, pp. 281-282
-
-
Cardozo, L.D.1
Stanton, S.L.2
Robinson, H.3
Hole, D.4
-
56
-
-
1642485727
-
Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: A prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping
-
Araki T, Yokoyama T, Kumon H: Effectiveness of a nonsteroidal anti-inflammatory drug for nocturia on patients with benign prostatic hyperplasia: a prospective non-randomized study of loxoprofen sodium 60 mg once daily before sleeping. Acta Med Okayama 2004, 58:45-49.
-
(2004)
Acta Med Okayama
, vol.58
, pp. 45-49
-
-
Araki, T.1
Yokoyama, T.2
Kumon, H.3
-
57
-
-
9644272488
-
-
•• Di Silverio F, Bosman C, Salvatori M, et al.: Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Eur Urol 2005, 47:72-78; discussion 78-79. This small clinical trial provides interesting data to suggest that NSAIDs may be a useful adjunct therapy for treating BPH-related LUTS.
-
•• Di Silverio F, Bosman C, Salvatori M, et al.: Combination therapy with rofecoxib and finasteride in the treatment of men with lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). Eur Urol 2005, 47:72-78; discussion 78-79. This small clinical trial provides interesting data to suggest that NSAIDs may be a useful adjunct therapy for treating BPH-related LUTS.
-
-
-
-
58
-
-
23044451172
-
-
•• Verhamme KM, Dieleman JP, Van Wijk MA, et al.: Nonsteroidal anti-inflammatory drugs and increased risk of acute urinary retention. Arch Intern Med 2005, 165:1547-1551. This large, retrospective, case-controlled study provides cautionary data suggesting that, in at least some men, new use of NSAIDs may actually trigger AUR.
-
•• Verhamme KM, Dieleman JP, Van Wijk MA, et al.: Nonsteroidal anti-inflammatory drugs and increased risk of acute urinary retention. Arch Intern Med 2005, 165:1547-1551. This large, retrospective, case-controlled study provides cautionary data suggesting that, in at least some men, new use of NSAIDs may actually trigger AUR.
-
-
-
-
59
-
-
0038792746
-
Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction
-
Partin JV, Anglin IE, Kyprianou N: Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction. Br J Cancer 2003, 88:1615-1621.
-
(2003)
Br J Cancer
, vol.88
, pp. 1615-1621
-
-
Partin, J.V.1
Anglin, I.E.2
Kyprianou, N.3
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