Down-regulation of macrophage inhibitory cytokine-1/prostate derived factor in benign prostatic hyperplasia

Prostate

Volumn 59, Issue 4, 2004, Pages 351-356

  Kakehi, Yoshiyuki ^a   Segawa, Takehiko ^b   Wu, Xiu Xian ^a   Kulkarni, Prakash ^c   Dhir, Rajiv ^d   Getzenberg, Robert H ^d  

^a KAGAWA UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Gene Logic Inc   (United States)

^d UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Androgen regulation; BPH; MIC 1; Prostate cancer

Indexed keywords

ANDROGEN; BONE MORPHOGENETIC PROTEIN; MACROPHAGE INHIBITORY CYTOKINE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROSTATE EPITHELIUM; PROSTATE HYPERTROPHY; PROSTATECTOMY; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; BONE MORPHOGENETIC PROTEINS; CYTOKINES; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PROSTATE; PROSTATIC HYPERPLASIA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 2442443317     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.10365     Document Type: Article

References (18)

1. Bootcov MR, Bauskin AR, Valenzuela SM, Moore A, Bansal M, He XY, zhang HP, Donnellan M, Mahler S, Pryor K, Walsh BJ, Nicholson RC, Fairlie WD, Por SB, Robbins JM, Brett SN. MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily. Proc Natl Acad Sci USA 1997;94: 11514-11519.
2. Hromas R, Hufford M, Sutton J, Xu D, Li Y, Lu L. PLAB, a novel placental bone morphogenetic protein. Biochem Biophys Acta 1997;1354:40-44.
3. Paralkar VM, Vail AL, Grasser WA, Brown TA, Xu H, Vukicevic S, Ke HZ, Qi H, Owen TA, Thompson DD. Cloning and characterization of a novel member of the transforming growth factor-β/bone morphogenetic p-protein family. J Biol Chem 1998;273:13760-13767.
4. Lawton LN, Bonaldo MF, Jelene PC, Qiu L, Baumes SA, Marcelino RA, deJesus GM, Wellington S, Knowles JA, Warburton D, Brown S, Soares MB. Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta. Gene 1997;203:17-26.
5. Strelau J, Bottner M, Lingor P, Suter-Crazzolara C, Galter D, Jaszai J, Sullivan A, Schober A, Kriegistein K, Unsicker K. GDF-15/MIC-1 a novelmember of the TGF-beta superfamily. J Neural Transm Suppl 2000;60:273-276.
6. Prakash K, Pirozzi G, Elashoff M, Munger W, Waga I, Dhir R, Kakehi Y, Getzenberg RH. Symptomatic and asymptomatic benign prostatic hyperplasia: Molecular differentiation using microarrays. Proc Natl Acad Sci USA 2002;99: 7598-7603.
7. Krill D, Shuman M, Thompson MT, Becich MJ, Strom SC. A simple method for the isolation and culture of epithelial and stromal cells from benign and neoplastic prostates. Urology 1997;49:981-988.
8. Tackels-Horne D, Goodman MD, Williams AJ, Wilson DJ, Eskandari T, Vogt LM, Boland JF, Scherf U, Vockley JG. Identification of differentiallay expressed genes in hepatocellular carcinoma and metastatic liver tumors by oligonucleotide expression profiling. Cancer 2001;92:395-405.
9. Young CY, Montgomery BT, Andrews PE, Qui SD, Bilhartz DL, Tindall DJ. Hormonal regulation of prostate-specific antigen messenger RNA in human prostatic adenocarcinoma cell line LNCaP. Cancer Res 1991;51:3748-3751.
10. Berry SJ, Coffey DS, Walsh PC, Ewing LL. The development of human benign prostatic hyperplasia with age. J Urol 1984;132: 474-479.
11. Moore AG, Brown DA, Fairlie WD, Bauskin AR, Brown PK, Munier MLC, Russell PK, Salamonsen LA, Wallace EM, Breit SN. The transforming growth factor-beta superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. J Clin Endocrinol Metab 2000;85:4781-4788.
12. Karan D, Kelly DL, Rizzino A, Lin M-F, Batra SK. Expression profile of differentially-regulated genes during progression of androgen-independent growth in human prostate cancer cells. Carcinogenesis 2002;23:967-976.
13. Welsh JB, Sapinoso LM, Su AI, Kern SG, Wang-Rodriguez J, Moskaluk CA, Frierson HF Jr., Hampton GM. Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res 2001;61: 5974-5978.
14. Nakamura T, Scorilas A, Stephan C, Yousef GM, Kristiansen G, Jung K, Diamandis EP. Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues. Br J Cancer 2003;88:1101-1104.
15. Krieg M, Nass R, Tunn S. Effect of aging on endogenous level of 5-alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. J Clin Endocrinol Metab 1993;77:375-381.
16. Kannan K, Amariglio N, Rechavi G, Givol D. Profile of gene expression regulated by induced p53: Connection to the TGF-beta family. FEBS Lett 2000;470:77-82.
17. Albertoni M, Shaw PH, Nozaki M, Godard S, Tenan M, Hamou MF, Fairlie DW, Breit SN, Paralkar VM, de Tribolet N, Van Meir EG, Hegi ME. Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1. Oncogene 2002;21:4212-4219.
18. Nickel JC, Downey J, Young I, Boag S. Asymptomatic inflammation and/or infection in benign prostatic hyperplasia. BJU Int 1999;84:976-981.