-
1
-
-
18344390450
-
The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling
-
Dunn KL, Espino P, Drobic B, He S, Davie JR. The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling. Biochem Cell Biol 2005;83:1-14.
-
(2005)
Biochem Cell Biol
, vol.83
, pp. 1-14
-
-
Dunn, K.L.1
Espino, P.2
Drobic, B.3
He, S.4
Davie, J.R.5
-
2
-
-
1542328273
-
Nucleosome remodeling: One mechanism, many phenomena?
-
Langst G, Becker PB. Nucleosome remodeling: one mechanism, many phenomena? Biochim Biophys Acta 2004;1677:58-63.
-
(2004)
Biochim Biophys Acta
, vol.1677
, pp. 58-63
-
-
Langst, G.1
Becker, P.B.2
-
3
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989;49:4682-9.
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
4
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007;26:3291-310.
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
CJ, D.2
-
6
-
-
0036358038
-
MAPK-regulated transcription: A continuously variable gene switch?
-
Hazzalin CA, Mahadevan LC. MAPK-regulated transcription: a continuously variable gene switch? Nat Rev Mol Cell Biol 2002;3:30-40.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 30-40
-
-
Hazzalin, C.A.1
Mahadevan, L.C.2
-
7
-
-
34547686501
-
Epigenetic mechanisms in stress-related memory formation
-
Reul JM, Chandramohan Y. Epigenetic mechanisms in stress-related memory formation. Psychoneuroendocrinology 2007;32(Suppl 1):S21-5.
-
(2007)
Psychoneuroendocrinology
, vol.32
, Issue.SUPPL. 1
-
-
Reul, J.M.1
Chandramohan, Y.2
-
8
-
-
0033609882
-
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts
-
Chadee DN, Hendzel MJ, Tylipski CP, Allis CD, Bazett-Jones DP, Wright JA, Davie JR. Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J Biol Chem 1999;274:24914-20.
-
(1999)
J Biol Chem
, vol.274
, pp. 24914-24920
-
-
Chadee, D.N.1
Hendzel, M.J.2
Tylipski, C.P.3
Allis, C.D.4
Bazett-Jones, D.P.5
Wright, J.A.6
Davie, J.R.7
-
9
-
-
21044450362
-
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2
-
Dyson MH, Thomson S, Inagaki M, Goto H, Arthur SJ, Nightingale K, Iborra FJ, Mahadevan LC. MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2. J Cell Sci 2005;118:2247-59.
-
(2005)
J Cell Sci
, vol.118
, pp. 2247-2259
-
-
Dyson, M.H.1
Thomson, S.2
Inagaki, M.3
Goto, H.4
Arthur, S.J.5
Nightingale, K.6
Iborra, F.J.7
Mahadevan, L.C.8
-
10
-
-
33646390099
-
Chromatin modification of the trefoil factor 1 gene in human breast cancer cells by the Ras/mitogen-activated protein kinase pathway
-
Espino PS, Li L, He S, Yu J, Davie JR. Chromatin modification of the trefoil factor 1 gene in human breast cancer cells by the Ras/mitogen-activated protein kinase pathway. Cancer Res 2006;66:4610-6.
-
(2006)
Cancer Res
, vol.66
, pp. 4610-4616
-
-
Espino, P.S.1
Li, L.2
He, S.3
Yu, J.4
Davie, J.R.5
-
11
-
-
36148991452
-
Phosphorylated serine 28 of histone H3 is associated with destabilized nucleosomes in transcribed chromatin
-
Sun JM, Chen HY, Espino PS, Davie JR. Phosphorylated serine 28 of histone H3 is associated with destabilized nucleosomes in transcribed chromatin. Nucleic Acids Res 2007;35:6640-7.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 6640-6647
-
-
Sun, J.M.1
Chen, H.Y.2
Espino, P.S.3
Davie, J.R.4
-
12
-
-
0038182524
-
MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14
-
Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, Mahadevan LC, Arthur JS. MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. EMBO J 2003;22:2788-97.
-
(2003)
EMBO J
, vol.22
, pp. 2788-2797
-
-
Soloaga, A.1
Thomson, S.2
Wiggin, G.R.3
Rampersaud, N.4
Dyson, M.H.5
Hazzalin, C.A.6
Mahadevan, L.C.7
Arthur, J.S.8
-
13
-
-
19444363852
-
Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28
-
Dunn KL, Davie JR. Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28. Oncogene 2005;24:3492-502.
-
(2005)
Oncogene
, vol.24
, pp. 3492-3502
-
-
Dunn, K.L.1
Davie, J.R.2
-
14
-
-
23844518230
-
Inducible covalent posttranslational modification of histone H3
-
Bode AM, Dong Z. Inducible covalent posttranslational modification of histone H3. Sci STKE 2005:re4.
-
(2005)
Sci STKE
-
-
Bode, A.M.1
Dong, Z.2
-
15
-
-
34248141223
-
Tumor-stroma interactions in pancreatic ductal adenocarcinoma
-
Mahadevan D, von Hoff DD. Tumor-stroma interactions in pancreatic ductal adenocarcinoma. Mol Cancer Ther 2007;6:1186-97.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1186-1197
-
-
Mahadevan, D.1
von Hoff, D.D.2
-
16
-
-
0036142892
-
Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts
-
Strelkov IS, Davie JR. Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts. Cancer Res 2002;62:75-8.
-
(2002)
Cancer Res
, vol.62
, pp. 75-78
-
-
Strelkov, I.S.1
Davie, J.R.2
-
17
-
-
10844281158
-
MSK1 activity and histone H3 phosphorylation in oncogene-transformed mouse fibroblasts
-
Drobic B, Espino PS, Davie JR. MSK1 activity and histone H3 phosphorylation in oncogene-transformed mouse fibroblasts. Cancer Res 2004;64:9076-9.
-
(2004)
Cancer Res
, vol.64
, pp. 9076-9079
-
-
Drobic, B.1
Espino, P.S.2
Davie, J.R.3
-
18
-
-
21344450516
-
Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation
-
Choi HS, Choi BY, Cho YY, Mizuno H, Kang BS, Bode AM, Dong Z. Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation. Cancer Res 2005;65:5818-27.
-
(2005)
Cancer Res
, vol.65
, pp. 5818-5827
-
-
Choi, H.S.1
Choi, B.Y.2
Cho, Y.Y.3
Mizuno, H.4
Kang, B.S.5
Bode, A.M.6
Dong, Z.7
-
19
-
-
42049108200
-
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation
-
Kim HG, Lee KW, Cho YY, Kang NJ, Oh SM, Bode AM, Dong Z. Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer Res 2008;68:2538-47.
-
(2008)
Cancer Res
, vol.68
, pp. 2538-2547
-
-
Kim, H.G.1
Lee, K.W.2
Cho, Y.Y.3
Kang, N.J.4
Oh, S.M.5
Bode, A.M.6
Dong, Z.7
-
20
-
-
33750465141
-
Comparing aurora A and aurora B as molecular targets for growth inhibition of pancreatic cancer cells
-
Warner SL, Munoz RM, Stafford P, Koller E, Hurley LH, von Hoff DD, Han H. Comparing aurora A and aurora B as molecular targets for growth inhibition of pancreatic cancer cells. Mol Cancer Ther 2006;5:2450-8.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2450-2458
-
-
Warner, S.L.1
Munoz, R.M.2
Stafford, P.3
Koller, E.4
Hurley, L.H.5
von Hoff, D.D.6
Han, H.7
-
21
-
-
0035986858
-
The impact of p53 loss on murine plasmacytoma development
-
Mai S, Wiener F. The impact of p53 loss on murine plasmacytoma development. Chromosome Res 2002;10:239-51.
-
(2002)
Chromosome Res
, vol.10
, pp. 239-251
-
-
Mai, S.1
Wiener, F.2
-
22
-
-
14644423344
-
Rearrangements of the telomeric region of mouse chromosome 11 in Pre-B ABL/MYC cells revealed by mBANDing, spectral karyotyping, and fluorescence in-situ hybridization with a subtelomeric probe
-
Benedek K, Chudoba I, Klein G, Wiener F, Mai S. Rearrangements of the telomeric region of mouse chromosome 11 in Pre-B ABL/MYC cells revealed by mBANDing, spectral karyotyping, and fluorescence in-situ hybridization with a subtelomeric probe. Chromosome Res 2004;12:777-85.
-
(2004)
Chromosome Res
, vol.12
, pp. 777-785
-
-
Benedek, K.1
Chudoba, I.2
Klein, G.3
Wiener, F.4
Mai, S.5
-
23
-
-
18344387814
-
Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein
-
Fest T, Guffei A, Williams G, Silva S, Mai S. Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein. Oncogene 2005;24:2944-53.
-
(2005)
Oncogene
, vol.24
, pp. 2944-2953
-
-
Fest, T.1
Guffei, A.2
Williams, G.3
Silva, S.4
Mai, S.5
-
25
-
-
33745610123
-
Cancer progression by non-clonal chromosome aberrations
-
Heng HH, Bremer SW, Stevens J, Ye KJ, Miller F, Liu G, Ye CJ. Cancer progression by non-clonal chromosome aberrations. J Cell Biochem 2006;98:1424-35.
-
(2006)
J Cell Biochem
, vol.98
, pp. 1424-1435
-
-
Heng, H.H.1
Bremer, S.W.2
Stevens, J.3
Ye, K.J.4
Miller, F.5
Liu, G.6
Ye, C.J.7
-
26
-
-
33745580375
-
Clonal and nonclonal chromosome aberrations and genome variation and aberration
-
Heng HH, Liu G, Bremer S, Ye KJ, Stevens J, Ye CJ. Clonal and nonclonal chromosome aberrations and genome variation and aberration. Genome 2006;49:195-204.
-
(2006)
Genome
, vol.49
, pp. 195-204
-
-
Heng, H.H.1
Liu, G.2
Bremer, S.3
Ye, K.J.4
Stevens, J.5
Ye, C.J.6
-
27
-
-
33745612099
-
Stochastic cancer progression driven by non-clonal chromosome aberrations
-
Heng HH, Stevens JB, Liu G, Bremer SW, Ye KJ, Reddy PV, Wu GS, Wang YA, Tainsky MA, Ye CJ. Stochastic cancer progression driven by non-clonal chromosome aberrations. J Cell Physiol 2006;208:461-72.
-
(2006)
J Cell Physiol
, vol.208
, pp. 461-472
-
-
Heng, H.H.1
Stevens, J.B.2
Liu, G.3
Bremer, S.W.4
Ye, K.J.5
Reddy, P.V.6
Wu, G.S.7
Wang, Y.A.8
Tainsky, M.A.9
Ye, C.J.10
-
29
-
-
33846168450
-
Genomic mechanisms and measurement of structural and numerical instability in cancer cells
-
Bayani J, Selvarajah S, Maire G, Vukovic B, Al-Romaih K, Zielenska M, Squire JA. Genomic mechanisms and measurement of structural and numerical instability in cancer cells. Semin Cancer Biol 2007;17:5-18.
-
(2007)
Semin Cancer Biol
, vol.17
, pp. 5-18
-
-
Bayani, J.1
Selvarajah, S.2
Maire, G.3
Vukovic, B.4
Al-Romaih, K.5
Zielenska, M.6
Squire, J.A.7
-
30
-
-
34547641984
-
Cancer genome sequencing: The challenges ahead
-
Heng HH. Cancer genome sequencing: the challenges ahead. Bio Essays 2007;29:783-94.
-
(2007)
Bio Essays
, vol.29
, pp. 783-794
-
-
Heng, H.H.1
-
31
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995;80:179-85.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
32
-
-
0035117119
-
Phorbol esters modulate the Ras exchange factor RasGRP3
-
Lorenzo PS, Kung JW, Bottorff DA, Garfield SH, Stone JC, Blumberg PM. Phorbol esters modulate the Ras exchange factor RasGRP3. Cancer Res 2001;61:943-9.
-
(2001)
Cancer Res
, vol.61
, pp. 943-949
-
-
Lorenzo, P.S.1
Kung, J.W.2
Bottorff, D.A.3
Garfield, S.H.4
Stone, J.C.5
Blumberg, P.M.6
-
33
-
-
38449089807
-
Targeted therapy of the epidermal growth factor receptor in the treatment of pancreatic cancer
-
Heeger S. Targeted therapy of the epidermal growth factor receptor in the treatment of pancreatic cancer. Recent Results Cancer Res 2008;177:131-6.
-
(2008)
Recent Results Cancer Res
, vol.177
, pp. 131-136
-
-
Heeger, S.1
-
34
-
-
38449087414
-
The role of the EGFR signaling in tumor microenvironment
-
de Luca A, Carotenuto A, Rachiglio A, Gallo M, Maiello MR, Aldinucci D, Pinto A, Normanno N. The role of the EGFR signaling in tumor microenvironment. J Cell Physiol 2008;214:559-67.
-
(2008)
J Cell Physiol
, vol.214
, pp. 559-567
-
-
de Luca, A.1
Carotenuto, A.2
Rachiglio, A.3
Gallo, M.4
Maiello, M.R.5
Aldinucci, D.6
Pinto, A.7
Normanno, N.8
-
35
-
-
38949183695
-
Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy
-
Friday BB, Adjei AA. Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy. Clin Cancer Res 2008;14:342-6.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 342-346
-
-
Friday, B.B.1
Adjei, A.A.2
-
36
-
-
38349193135
-
Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells
-
Stephens B, Han H, Hostetter G, Demeure MJ, von Hoff DD. Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells. Mol Cancer Ther 2008;7:202-10.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 202-210
-
-
Stephens, B.1
Han, H.2
Hostetter, G.3
Demeure, M.J.4
von Hoff, D.D.5
-
37
-
-
0037434930
-
The function of the protein tyrosine phosphatase SHP-1 in cancer
-
Wu C, Sun M, Liu L, Zhou GW. The function of the protein tyrosine phosphatase SHP-1 in cancer. Gene 2003;306:1-12.
-
(2003)
Gene
, vol.306
, pp. 1-12
-
-
Wu, C.1
Sun, M.2
Liu, L.3
Zhou, G.W.4
|