6-Thioguanine in DNA as CD-spectroscopic probe to study local structural changes upon protein binding

Chirality

Volumn 20, Issue 9, 2008, Pages 978-984

  Repges, Rudolf ^a   Beuck, Christine ^a   Weinhold, Elmar ^a   Raabe, Gerhard ^a   Fleischhauer, Jorg ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

6 thioguanine; Circular dichroism; DNA; M.TaqI; Matrix method calculations; Protein binding; Structural changes

Indexed keywords

ADENINE; CYTOSINE; DNA; DNA METHYLTRANSFERASE; GUANINE; NUCLEIC ACID BASE; THYMINE; TIOGUANINE; NUCLEIC ACID; TCGA SPECIFIC TYPE II DEOXYRIBONUCLEASES; TCGA-SPECIFIC TYPE II DEOXYRIBONUCLEASES; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE; UNCLASSIFIED DRUG;

BINDING KINETICS; CHEMICAL STRUCTURE; CHROMATOPHORE; CIRCULAR DICHROISM; CONFERENCE PAPER; CONTROLLED STUDY; DENSITY FUNCTIONAL THEORY; DNA BINDING; DNA MODIFICATION; DNA STRUCTURE; MOLECULAR PROBE; PRIORITY JOURNAL; PROTEIN BINDING; QUALITATIVE ANALYSIS; SIGNAL PROCESSING; ARTICLE; CHEMISTRY; CONFORMATION; ENZYMOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; THERMUS;

CIRCULAR DICHROISM; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMUS; THIOGUANINE;

EID: 58149269563     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20540     Document Type: Conference Paper

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