Development and evaluation of the sinomenine transdermal patch

Pakistan Journal of Pharmaceutical Sciences

Volumn 21, Issue 4, 2008, Pages 407-410

  Wang, Jianping ^a   Ruan, Jinlan ^a   Zhang, Changgong ^a   Ye, Yujie ^b   Cai, Yaling ^a   Wu, Yunxia ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Peel test; Sinomenine; Skin irritation test; Transdermal patch

Indexed keywords

ANTIRHEUMATIC AGENT; EXCIPIENT; MORPHINAN DERIVATIVE; SINOMENINE; TISSUE ADHESIVE;

ADHESION; ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG DOSAGE FORM; EDEMA; ERYTHEMA; EVALUATION; INTRADERMAL DRUG ADMINISTRATION; KINETICS; MALE; METABOLISM; MOUSE; PERMEABILITY; SKIN; SKIN ABSORPTION; SOLUBILITY; TOXICITY TESTING;

ADHESIVENESS; ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIRHEUMATIC AGENTS; CHEMISTRY, PHARMACEUTICAL; DOSAGE FORMS; EDEMA; ERYTHEMA; EXCIPIENTS; KINETICS; MALE; MICE; MORPHINANS; PERMEABILITY; SKIN; SKIN ABSORPTION; SKIN IRRITANCY TESTS; SOLUBILITY; TISSUE ADHESIVES;

EID: 58149250924     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. China Pharmacopoeia Committee-CPC (2005). Chinese Pharmacopoeia (I), Chemical Industry Press, Beijing, p.135.
2. Draize, Woodard G and Calvery H (2000). Methods for the study of irritation and toxicity of substances topically applied to skin and mucous membranes. J. Pharmacol. Expe. Ther., 82: 377-390.
3. Liu Q, Zhou LL and Li R. General development of sinomenine in chemistry, pharmacology and clinics. Chin. Tradit. Herb. Drugs, 28: 247-249.
4. Liu Q, Zhou LL and Li R (1999). Study on releasing rate of sinomenine TDD. Chin. Tradit. Pa. Med., 21: 279-281.
5. Paola M, Francesco C and Leila T (2003). Design of a New Water-Soluble Pressure-Sensitive Adhesive for Patch Preparation. AAPS Pharm. Sci. Tech., 4: 53-61.
6. Tardiff RG, Hubner RP and Graves CG (2003). Harmonization of thresholds for primary skin irritation from results of human repeated insult patch tests and laboratory animal skin irritation tests. Toxicol. Appl. Pharmaco., 23: 279-281.
7. Venkatraman S and Gale R (1998). Skin adhesives and skin adhesion: 1. Transdermal drug delivery systems. Biomaterials, 19: 1119-1136.
8. Yoshinori O, Masaru H and Hideaki O (2005). Formulation optimization of photocrosslinked polyacrylic acid modified with 2-hydroxyethyl methacrylate hydrogel as an adhesive for a dermatological patch. J. Control. Release, 108: 331-340.