Harmonization of thresholds for primary skin irritation from results of human repeated insult patch tests and laboratory animal skin irritation tests

Journal of Applied Toxicology

Volumn 23, Issue 4, 2003, Pages 279-281

  Tardiff, Robert G ^a   Hubner, Richard P ^a   Graves, Carol Gevecker ^a  

^a The Sapphire Group Inc   (United States)

Author keywords

Animal test; Harmonization; Human RIPT; Repeated insult patch tests; Scoring; Skin irritation

Indexed keywords

COSMETIC; IRRITANT AGENT;

ANIMAL WELFARE; ARTICLE; CHEMICAL ANALYSIS; CLINICAL PROTOCOL; HUMAN; INTERMETHOD COMPARISON; LABORATORY TEST; NONHUMAN; PATCH TEST; PRIORITY JOURNAL; RATING SCALE; REFERENCE VALUE; SCORING SYSTEM; SKIN IRRITATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; HUMANS; INTERNATIONAL COOPERATION; IRRITANTS; PATCH TESTS; RABBITS; SKIN; SKIN IRRITANCY TESTS;

ANIMALIA;

EID: 0043201341     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.917     Document Type: Article

References (5)

1. Buehler EV, Griffith JF. 1975. Experimental skin sensitization in the guinea pig and man. In Animal Models in Dermatology: Relevance to Human Dermatopharmacology and Dermatotoxicology, Maibach H (ed.). Churchill Livingstone: New York; 56-66.
2. Consumer Products Safety Commission (CPSC). 1996. Method of Testing and Evaluating Primary Irritant Substances, 16 CFR 1500.41. CPSC: Washingto DC, USA.
3. Klecak G. 1998. Test methods for allergic contact dermatitis in animals. In Dermatotoxicology Methods: the Laboratory Workers vade mecum, Marzulli FN, Maibach HI (eds). Taylor & Francis: Washington, DC; 121-143.
4. Marzulli FN, Maibach HI. 1998. Test methods for allergic contact dermatitis in humans. In Dermatotoxicology Methods: the Laboratory Workers vade mecum, Marzulli FN, Maibach HI (eds). Taylor & Francis: Washington, DC; 153-159.
5. Patil SM, Patrick E, Maibach HI. 1998. Animal, human, and in vitro test methods for predicting skin irritation. In Dermatotoxicology Methods: the Laboratory Workers vade mecum, Marzulli FN, Maibach HI (eds). Taylor & Francis: Washington, DC; 89-114.