Chemical modification of pectins, characterization and evaluation for drug delivery

Scientia Pharmaceutica

Volumn 76, Issue 4, 2008, Pages 775-784

  Bhatia, Manish S ^a   Choudhari, Praffula ^a   Bhatia, Neela M ^a   Deshmukh, Rameshwar ^a  

^a SHIVAJI UNIVERSITY   (India)

Author keywords

Chemical modification; Ibuprofen; Pectins; Release profile

Indexed keywords

CHLOROFORM; HYDROXYL GROUP; IBUPROFEN; METHANOL; PECTIN; WATER;

CHEMICAL MODIFICATION; DRUG ACETYLATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; GASTROINTESTINAL ABSORPTION; INTESTINE TRANSIT TIME; MATHEMATICAL MODEL; NONHUMAN; PHYSICAL CHEMISTRY; REVIEW; TABLET FORMULATION;

EID: 58149236984     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.0805-23     Document Type: Review

References (17)

1. Liu L S., Fishman M L, Kost J, Hicks K B. Pectin-based systems for colon-specific drug delivery via oral route. Biomaterials. 2003; 24: 3333-3343. doi:10.1016/S0142-9612(03)00213-8
2. Ugurlu T, Turkoglu M, Gurer U S, Akarsu B G. Colonic delivery of compression coated nisin tablets using pectin/HPMC polymer mixture. Eur J Pharm Biopharm. 2007; 67: 202-210. doi:10.1016/j.ejpb.2007.01.016
3. International Pectin Producers Association http://www.ippa.info
4. Cybercolloids Ltd. http://www.cybercolloids.net/library/pectin/ properties.php (accepted 26 May 2005)
5. Kudela V Hydrogels Encyclopedia of Polymer Science and Engineering. Wiley, New York. 1987; 7: 703-807.
6. Bamba M, Puisieux F. Release mechanism in gel forming sustained release preparation. Int J Pharm. 1979; 2: 307-315. doi:10.1016/0378-5173(79)90037-1
7. Sande S A. Pectin-based oral drug delivery to the colon. Expert Opin Drug Deliv. 2005; 2: 441-450. doi:10.1517/17425247.2.3.441
8. Baojian W, Daoyin D, Yi L, Wei W. Biphasic release of indomethacin from HPMC/Pectin/Calcium matrix tablet: II. Influencing Variables, stability and Pharmacokinetics in dogs. Eur J Pharm Biopharm. 2008; 69: 294-302. doi:10.1016/j.ejpb.2007.10.001
9. Sinha V R, Kumria R. Microbiologically triggered drug delivery to the colon. Eur J Pharm Sci. 2003; 18: 3-18. doi: 10.1016/S0928-0987(02)00221 -X
10. Ofari-Kwakye K, Fell J T. Leaching of pectin from mixed films containing pectin, chitosan and HPMC intended for biphasic drug delivery. Int J Pharm. 2003; 250: 251-257. doi:10.1016/S0378-5173(02)00546-X
11. Ahrabi S F, Madsen G, Dyrstadb K, Sandea S A, Graffner C. Development of pectin matrix tablets for colonic delivery of model drug ropivacaine. Eur J Pharm Sci. 2000; 10: 43-52. doi:10.1016/S0928-0987(99)00087-1
12. Macleod G S, Fell J T, Collett J H, Sharma H L, Smith A -M. Selective drug delivery to the colon usng pectin:chitosan:hydroxypropyl methylcellulose film coated tablets. Int J Pharm. 1999; 187: 251-257. doi:10.1016/S0378-5173(99) 00196-9
13. Wakerly Z, Fell J T, Attwood D, Parkins D A. In vitro evaluation of pectin based colonic drug delivery systems. Int J Pharm. 1996; 129: 73-77. doi: 10.1016/0378-5173(95)04251-2
14. Kupchik L A, Kartel N T, Bogdanov E S, Bogdanov O V, Kupchik M P. [Chemical modification of pectin to improve its sorption properties]. Zh Prikl Khim. 2006; 79: 464-467. Russ J Appl Chem. 2006; 79: 457-460. doi: 10.1134/S1070427206030256
15. Dongowski G, Schnorrenberger B, Pitzer M, Schwarz M, Neubert R. Interaction between food components and drugs. Part 5: Effect of acetylation and amidation of pectins on the interaction with drug. Int J Pharm. 1997; 158: 99-107. doi: 10.1016/S0378-5173(97)00252-4
16. United State of Pharmacopoeia 23, 1791.
17. Indian pharmacopoeia, Vol. II, Appendix 13.1 & 13.5, A-147 & A-211, (1996).