Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase α inhibitor, on DNA replication in cultured cells

Molecules

Volumn 13, Issue 12, 2008, Pages 2948-2961

  Kuriyama, Isoko ^a   Mizuno, Takeshi ^b   Fukudome, Keishi ^c   Kuramochi, Kouji ^d   Tsubaki, Kazunori ^d   Usui, Takeo ^e   Imamoto, Naoko ^b   Sakaguchi, Kengo ^c   Sugawara, Fumio ^c   Yoshida, Hiromi ^a   Mizushina, Yoshiyuki ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d KYOTO PREFECTURAL UNIVERSITY   (Japan)

^e UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Anticancer drug; Dehydroaltenusin C12 (C12); DNA polymerase (DNA directed DNA polymerase E.C. 2.7.7.7 , pol) ; DNA replication; Enzyme inhibitor; Hypotonic shift; Molecule probe; Replication fork uncoupling

Indexed keywords

BENZOPYRAN DERIVATIVE; DEHYDROALTENUSIN; DNA DIRECTED DNA POLYMERASE BETA; ENZYME INHIBITOR;

ANIMAL; ARTICLE; CELL STRAIN 3T3; DNA REPLICATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; MOUSE;

ANIMALS; BENZOPYRANS; DNA POLYMERASE I; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; MICE; NIH 3T3 CELLS;

EID: 58149236866     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules13122948     Document Type: Article

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