Pregnancy and the risk of torsades de pointes in congenital long-QT syndrome

Netherlands Heart Journal

Volumn 16, Issue 12, 2008, Pages 422-425

  Meregalli, P G ^a   Westendorp, I C D ^b   Tan, H L ^a   Elsman, P ^c   Kok, W E M ^a   Wilde, A A M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RED CROSS HOSPITAL   (Netherlands)

^c JEROEN BOSCH HOSPITAL   (Netherlands)

Author keywords

Beta blocker; Genetic; Long QT syndrome; Pregnancy

Indexed keywords

ALDOSTERONE ANTAGONIST; BISOPROLOL; GENE PRODUCT; MAGNESIUM SULFATE; METOPROLOL; POTASSIUM; POTASSIUM CHANNEL KCNH2; POTASSIUM CHANNEL KV1.1; UNCLASSIFIED DRUG;

ADULT; ANAMNESIS; ARTICLE; BRADYCARDIA; CASE REPORT; DEFIBRILLATOR; DELIVERY; ELECTROCARDIOGRAM; ELECTROCARDIOGRAPHY MONITORING; FEMALE; GENE MUTATION; HEART ARRHYTHMIA; HEART VENTRICLE EXTRASYSTOLE; HUMAN; LABORATORY TEST; LONG QT SYNDROME; NULLIPARA; PREGNANCY; QT INTERVAL; QT PROLONGATION; RISK ASSESSMENT; RR INTERVAL; SINUS RHYTHM; SYNCOPE; TORSADE DES POINTES;

EID: 58149233996     PISSN: 15685888     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03086191     Document Type: Article

References (10)

1. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS. Diagnostic criteria for the long QT syndrome. An update. Circulation 1993;88:782-4.
2. Roden DM. Clinical practice. Long-QT syndrome. N Engl J Med 2008;358:169-76.
3. Jackman WM, Friday KJ, Anderson JL, Aliot EM, Clark M, Lazzara R. The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis. Prog Cardiovasc Dis 1988;31:115-72.
4. Splawski I, Shen J, Timothy KW, Lehmann MH, Priori S, Robinson JL, et al. Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2. Circulation 2000;102:1178-85.
5. Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, et al. Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation 2001;103:89-95.
6. Conrath CE, Jongbloed RJE, van Langen IM, van Tintelen, Hauer RNW, Robles de Medina EO, et al. Gene-specific distribution of cardiac events in LQTS1 and LQTS2. Neth Heart J 1999;6:254-9.
7. Wilde AA, Jongbloed RJ, Doevendans PA, Duren DR, Hauer RN, van Langen I, et al. Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KVLQT1-related patients (LQTS1). J Am Coll Cardiol 1999; 33:327-32.
8. Seth R, Moss AJ, McNitt S, Zareba W, Andrews ML, Qi M, et al. Long QT syndrome and pregnancy. J Am Coll Cardiol 2007;49: 1092-8.
9. Tan HL, Alings M, Van Olden RW, Wilde AA. Long-term (subacute) potassium treatment in congenital HERG-related long QT syndrome (LQTS2). J Cardiovasc Electrophysiol 1999;10:229-33.
10. Rashba EJ, Zareba W, Moss AJ, Hall WJ, Robinson J, Locati EH, et al. Influence of pregnancy on the risk for cardiac events in patients with hereditary long QT syndrome. LQTS Investigators. Circulation 1998;97:451-6.