Core mutations in patients with acute episodes of chronic HBV infection are associated with the emergence of new immune recognition sites and the development of high IgM Anti-HBc index values

Journal of Medical Virology

Volumn 81, Issue 1, 2009, Pages 34-41

  Alexopoulou, Alexandra ^a,c   Baltayiannis, Gerassimos ^b   Eroglu, Cafer ^b   Nastos, Theodoros ^b   Dourakis, Spyros P ^a   Archimandritis, Athanasios J ^a   Karayiannis, Peter ^b  

^a HIPPOKRATION HOSPITAL   (Greece)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c NONE   (Greece)

Author keywords

Acute exacerbations; Core variants; HBeAg negative patients; Immune epitopes; Quasispecies

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; AMINO ACID; CLOTIAZEPAM; CORE PROTEIN; EPITOPE; HEPATITIS B CORE ANTIBODY; HEPATITIS B(E) ANTIGEN; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; VIRUS RNA; HEPATITIS B ANTIBODY; HEPATITIS B CORE ANTIGEN; VIRUS DNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBODY PRODUCTION; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CHRONIC DISEASE; CHRONIC HEPATITIS; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; FOLLOW UP; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MALE; MOLECULAR CLONING; RNA SEQUENCE; T LYMPHOCYTE; VIRUS CORE; VIRUS MUTANT; VIRUS MUTATION; BLOOD; CHEMISTRY; DNA SEQUENCE; GENETICS; IMMUNOLOGY; LONGITUDINAL STUDY; MIDDLE AGED; MISSENSE MUTATION; VIROLOGY;

HEPATITIS B VIRUS;

ADULT; DNA, VIRAL; EPITOPES; FEMALE; HEPATITIS B ANTIBODIES; HEPATITIS B CORE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; IMMUNOGLOBULIN M; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MUTATION, MISSENSE; SEQUENCE ANALYSIS, DNA;

EID: 58149230056     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21337     Document Type: Article

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