Effect of biocatalyst swelling on the operation of packed-bed immobilized enzyme bioreactor

Process Biochemistry

Volumn 44, Issue 2, 2009, Pages 183-190

  Mammarella, Enrique J ^a   Rubiolo, Amelia C ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

Author keywords

Bed swelling; Mathematical model; Packed bed immobilized enzyme reactor

Indexed keywords

CALCIUM; COLLOIDS; ENZYME INHIBITION; ENZYMES; FUNCTIONS; GELATION; PACKED BEDS; REACTION KINETICS; SUGARS;

AXIAL DISPERSIONS; BED REACTORS; BED SWELLING; CARRAGEENAN GELS; EXPERIMENTAL DATUMS; EXTERNAL MASS TRANSFERS; GALACTOSIDASE; IMMOBILIZED ENZYMES; LACTOSE HYDROLYSIS; NUMERICAL SOLUTIONS; PACKED-BED IMMOBILIZED ENZYME REACTOR; PRODUCT INHIBITIONS;

MATHEMATICAL MODELS;

EID: 58149216440     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2008.10.009     Document Type: Article

References (21)

1. Luh N., Flink J., and Karel M. Fabrication, characterization, and modification of the texture of calcium alginate gels. J Food Sci 42 (1977) 976-981
2. Woodward J., Krasniak S., Smith R., Spielberg F., and Zachry G. Preparation and characterization of β-d-glucosidase immobilized in calcium alginate. Biotechnol Bioeng Symp 12 (1982) 485-489
3. Mammarella E., and Rubiolo A. Response surface methodology to optimize β-galactosidase immobilization using a combination of hydrocolloids as the supporting matrix. Biotechnol Prog 12 (1996) 612-617
4. Mammarella E., and Rubiolo A. Study of the deactivation of β-galactosidase entrapped in alginate-carrageenan gels. J Mol Catal B Enzym 34 (2005) 7-13
5. Mammarella E., and Rubiolo A. Predicting the packed-bed reactor performance with immobilized microbial lactase. Process Biochem 41 (2006) 1627-1636
6. Doherty E., Halling P., and McNeil B. Physiology of immobilised cells (1990), Elsevier, Amsterdam, Netherlands
7. Tuncel A. An engineering analysis for the continuous reactor behaviour of α-chymotrypsin-immobilized thermosensitive gel cylinders. J Biotechnol 63 (1998) 41-54
8. Shadday M. A one-dimensional transient model of down-flow through a swelling packed porous bed. Chem Eng Sci 61 (2006) 2688-2700
9. Sainio T., and Paatero E. Mass coordinates for dynamic simulation of column operation involving dimensional changes of packing material. Comp Chem Eng 31 (2007) 374-383
10. Carrara C., Mammarella E., and Rubiolo A. Prediction of the fixed-bed reactor behaviour using dispersion and plug-flow models with different kinetics for immobilised enzyme. Chem Eng J 92 (2003) 123-129
11. Henley S., and Sadana T. Deactivation theory. Biotechnol Bioeng 28 (1986) 1277-1285
12. Illanes A, Wilson L, Altamirano C, Aillapán A. Reactor performance under thermal inactivation and temperature optimization with chitin-immobilized lactase. In: Progress in biotechnology, vol. 15. Stability and stabilization of biocatalysts. Amsterdam, Netherlands: Elsevier; 1998.
13. Giacomini C., Irazoqui G., Batista-Viera F., and Brena B. Influence of the immobilization chemistry on the properties of immobilized β-galactosidases. J Mol Catal B Enzym 11 (2001) 597-606
14. Brena B., Irazoqui G., Giacomini C., and Batista-Viera F. Effect of increasing co-solvent concentration on the stability of soluble and immobilized β-galactosidase. J Mol Catal B Enzym 21 (2003) 25-29
15. Rodriguez-Nogales J., and Delgadillo A. Stability and catalytic kinetics of microencapsulated β-galactosidase in liposomes prepared by the dehydration-rehydration method. J Mol Catal B Enzym 33 (2005) 15-21
16. Finlayson B.A. Nonlinear analysis in chemical engineering (1980), McGraw-Hill, New York, USA
17. Al-Muftah A.E., and Abu-Reesh I.M. Effects of simultaneous internal and external mass transfer and product inhibition on immobilized enzyme-catalyzed reactor. Biochem Eng J 27 (2005) 167-178
18. Geankoplis C. Procesos de transporte y operaciones unitarias (1999), Compañía Editorial Continental S.A. de C.V, México, México
19. Levenspiel O. The chemical reactor omnibook (1979), OSU Book Stores, Corvallis, USA
20. Axelsson A., Sisak C., Westrin B., and Szajáni B. Diffusional characteristics of a swelling gel and its consequences for bioreactor performance. Chem Eng J 55 (1994) B35-B39
21. Pitcher W. Design and analysis of immobilized enzyme reactor. In: Immobilized enzymes for industrial reactors (1975), Academic Press, Oxford, UK