Evaluation of the physical stability of the EC5 domain of E-cadherin: Effects of pH, temperature, ionic strength, and disulfide bonds

Journal of Pharmaceutical Sciences

Volumn 98, Issue 1, 2009, Pages 63-73

  Zheng, Kai ^a   Middaugh, C Russell ^a   Siahaan, Teruna J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

CD; EC5; Intrinsic fluorescence; Optical density; Phase diagram; Protein stability; UV absorbance

Indexed keywords

RECOMBINANT PROTEIN; UVOMORULIN;

ARTICLE; CIRCULAR DICHROISM; DISULFIDE BOND; FLUORESCENCE SPECTROSCOPY; IONIC STRENGTH; PH; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; TEMPERATURE DEPENDENCE; ULTRAVIOLET SPECTROSCOPY;

EID: 58149213971     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21418     Document Type: Article

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