The absence of high-risk HPV combined with specific p53 and p16INK4a expression patterns points to the HPV-independent pathway as the causative agent for vulvar squamous cell carcinoma and its precursor simplex VIN in a young patient

International Journal of Gynecological Pathology

Volumn 27, Issue 4, 2008, Pages 591-595

  Kruse, Arnold Jan ^a   Bottenberg, Marcel J H ^a   Tosserams, Janna ^a   Slangen, Brigitte ^a   Van Marion, Ariënne M W ^a   Van Trappen, Philippe O ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

HPV; Immunohistochemistry; SCC; Simplex VIN; Vulva

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; PROTEIN P53; VIRUS DNA; TP53 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CASE REPORT; DIFFERENTIAL DIAGNOSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; VULVA; VULVA CARCINOMA; VULVA TUMOR; VULVAR INTRAEPITHELIAL NEOPLASIA; WART VIRUS; BIOSYNTHESIS; FEMALE; GENETICS; METABOLISM; PAPILLOMA VIRUS; PATHOLOGY; VIROLOGY; VIRUS INFECTION;

ADULT; CARCINOMA, SQUAMOUS CELL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA, VIRAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; TUMOR SUPPRESSOR PROTEIN P53; VULVAR NEOPLASMS;

EID: 58149198220     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/PGP.0b013e318178e53b     Document Type: Article

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