Pharmacokinetic study of three active flavonoid glycosides in rat after intravenous administration of Trollius ledobourii extract by liquid chromatography

Biomedical Chromatography

Volumn 22, Issue 10, 2008, Pages 1130-1136

  Li, Deqiang ^a   Wang, Qiao ^a   Xu, Lei ^a   Li, Min ^a   Jing, Xiujuan ^a   Zhang, Langtong ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

HPLC analysis; Orientin; Orientin 2 O L galactopyranosyl (OGA); Pharmacokinetics; Trollius ledebourii extract; Vitexin

Indexed keywords

BODY FLUIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RATS; SUGARS;

FLAVONOID GLYCOSIDES; HPLC ANALYSIS; INTRAVENOUS ADMINISTRATION; ORIENTIN; ORIENTIN-2″-O-Β-L-GALACTOPYRANOSYL; PHARMACOKINETIC STUDIES; RAT PLASMA; SIMULTANEOUS DETERMINATIONS; TROLLIUS LEDEBOURII EXTRACT; VITEXIN;

PHARMACOKINETICS;

ACETIC ACID; ACETONITRILE; FLAVONOID; FLAVONOID GLYCOSIDE; HERBACEOUS AGENT; METHANOL; ORIENTIN; ORIENTIN 2'' O BETA GALACTOPYRANOSYL; TROLLIUS LEDEBOURII EXTRACT; UNCLASSIFIED DRUG; VITEXIN; APIGENIN; GALACTOSIDE; GLUCOSIDE; PLANT EXTRACT;

ACCURACY; ANALYTICAL ERROR; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG ISOLATION; DRUG STRUCTURE; ELUTION; MALE; MEAN RESIDENCE TIME; NONHUMAN; PRECIPITATION; PROCESS DEVELOPMENT; PRODUCT RECOVERY; RANUNCULACEAE; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; TROLLIUS LEDEBOURII; VALIDATION PROCESS; ANIMAL; CHEMISTRY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; VALIDATION STUDY;

RATTUS; TROLLIUS; TROLLIUS LEDEBOURI;

ANIMALS; APIGENIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FLAVONOIDS; GALACTOSIDES; GLUCOSIDES; INJECTIONS, INTRAVENOUS; MALE; PLANT EXTRACTS; RANUNCULACEAE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 58149149977     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1035     Document Type: Article

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