An immunoassay for human serum hepcidin at last: Ganz klar?

Blood

Volumn 112, Issue 10, 2008, Pages 3922-3923

  Brugnara, Carlo ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; FERROPORTIN; HEPCIDIN; IRON; ANTIMICROBIAL CATIONIC PEPTIDE; C REACTIVE PROTEIN;

BLOOD DONOR; DUODENUM; HORMONE BLOOD LEVEL; HORMONE URINE LEVEL; HUMAN; IMMUNOASSAY; IRON ABSORPTION; IRON DEFICIENCY ANEMIA; IRON METABOLISM; IRON OVERLOAD; IRON THERAPY; MACROPHAGE; MOLECULAR BIOLOGY; NOTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; BLOOD; CHRONIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMOCHROMATOSIS; INFLAMMATION; KIDNEY DISEASE; MALE; MULTIPLE MYELOMA; SENSITIVITY AND SPECIFICITY; URINE;

ANEMIA, IRON-DEFICIENCY; ANTIMICROBIAL CATIONIC PEPTIDES; C-REACTIVE PROTEIN; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FERRITINS; HEMOCHROMATOSIS; HUMANS; INFLAMMATION; IRON; KIDNEY DISEASES; MALE; MULTIPLE MYELOMA; SENSITIVITY AND SPECIFICITY;

EID: 58149147643     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-09-176701     Document Type: Note

References (7)

1. Peyssonnaux C, Zinkernagel AS, Schuepbach RA, et al. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest. 2007;117: 1926-1932.
2. Kemna E, Tjalsma H, Laarakkers C, et al. Novel urine hepcidin assay by mass spectrometry. Blood. 2005;106: 3268-3270.
3. Murphy AT, Witcher DR, Luan P, et al. Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry. Blood. 2007; 110:1048-1054.
4. Mast AE, Foster TM, Pinder HL, et al. Behavioral, biochemical, and genetic analysis of iron metabolism in high-intensity blood donors. Transfusion. 2008;48:2197- 2204.
5. Roe MA, Spinks C, Heath AL, et al. Serum prohepcidin concentration: no association with iron absorption in healthy men; and no relationship with iron status in men carrying HFE mutations, hereditary haemochromatosis patients undergoing phlebotomy treatment, or pregnant women. Br J Nutr. 2007;97:544-549.
6. Finberg KE, HeeneyMM,Campagna DR, et al. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet. 2008;40:569-571.
7. Du X, She E, Gelbart T, et al. The serine protease TMPRSS6 is required to sense iron deficiency. Science. 2008;320:1088-1092.