Limitations of intrathecal baclofen for spastic hemiparesis following stroke

Neurorehabilitation and Neural Repair

Volumn 23, Issue 1, 2009, Pages 26-31

  Kofler, Markus ^a   Quirbach, Ellen ^a   Schauer, Robert ^a   Singer, Markus ^a   Saltuari, Leopold ^a  

^a Hospital Hochzirl   (Austria)

Author keywords

Gait; Intrathecal baclofen; Spasticity; Stroke

Indexed keywords

BACLOFEN;

ADULT; ALERTNESS; ANTINOCICEPTION; ARTICLE; BLOOD PRESSURE; BOLUS INJECTION; CATHETER; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTINUOUS INFUSION; DRUG INJECTION VOLUME; FATIGUE; FEMALE; GENERAL CONDITION DETERIORATION; HEART RATE; HEMIPARESIS; HUMAN; MALE; MOBILIZATION; MOTOR CONTROL; MUSCLE TONE; MUSCLE WEAKNESS; RESIDUAL URINE; RESPIRATION DEPRESSION; SCHOOL CHILD; SEIZURE; SIDE EFFECT; STROKE; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; URETHRAL CATHETERIZATION; URINE INCONTINENCE; VERTIGO; VIDEORECORDING; WALKING;

ADOLESCENT; ADULT; BACLOFEN; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GABA AGONISTS; GAIT DISORDERS, NEUROLOGIC; HUMANS; INJECTIONS, SPINAL; MALE; MIDDLE AGED; MOTOR NEURONS; MUSCLE SPASTICITY; MUSCLE TONUS; MUSCLE WEAKNESS; MUSCLE, SKELETAL; PAIN; PARESIS; SPINAL CORD; STROKE; YOUNG ADULT;

EID: 58149144757     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968308317700     Document Type: Article

References (36)

1. Penn RD, Kroin JS Continuous intrathecal baclofen for severe spasticity. Lancet. 1985 ; 2 (8447). 125-127.
2. Coffey RJ, Cahill D., Steers W., et al. Intrathecal baclofen for intractable spasticity of spinal origin: results of a long-term multicenter study. J Neurosurg. 1993 ; 78: 226-232.
3. Saltuari L., Kronenberg M., Marosi M., et al. Long-term intrathecal baclofen treatment in supraspinal spasticity. Acta Neurol (Napoli). 1992 ; 47: 195-207.
4. Meythaler JM, DeVivo MJ, Hadley M. Prospective study on the use of bolus intrathecal baclofen for spastic hypertonia due to acquired brain injury. Arch Phys Med Rehabil. 1996 ; 77: 461-466.
5. Becker R., Alberti O., Bauer BL Continuous intrathecal baclofen infusion in severe spasticity after traumatic or hypoxic brain injury. J Neurol. 1997 ; 244: 160-166.
6. Albright AL Baclofen in the treatment of cerebral palsy. J Child Neurol. 1996 ; 11: 77-83.
7. Meythaler JM, Guin-Renfroe S., Brunner RC, Hadley MN Intrathecal baclofen for spastic hypertonia from stroke. Stroke. 2001 ; 32: 2099-2109.
8. Francisco GE, Boake C. Improvement in walking speed in poststroke spastic hemiplegia after intrathecal baclofen therapy: a preliminary study. Arch Phys Med Rehabil. 2003 ; 84: 1194-1199.
9. Ivanhoe CB, Francisco GE, McGuire JR, Subramanian T., Grissom P. Intrathecal baclofen management of poststroke spastic hypertonia: implications for function and quality of life. Arch Phys Med Rehabil. 2006 ; 87: 1509-1515.
10. Young RR, Delwaide PJ Drug therapy-spasticity. Part II. N Engl J Med. 1981 ; 304: 96-99.
11. O'Brien CF, Seeberger LC, Smith DB Spasticity after stroke. Epidemiology and optimal treatment. Drugs Aging. 1996 ; 9: 332-340.
12. Francisco GE Can intrathecal baclofen therapy unleash functional recovery after stroke ? Stroke. 2001 ; 32: 2108-2109.
13. Dones I., Nazzi V., Tringali G., Broggi G. Cautious use of intrathecal baclofen in walking spastic patients: results on long-term follow-up. Neuromodulation. 2006 ; 9: 87-93.
14. Gerszten PC, Albright AL, Barry MJ Effect on ambulation of continuous intrathecal baclofen infusion. Pediatr Neurosurg. 1997 ; 27: 40-44.
15. Sadiq S., Wang G. Long-term intrathecal baclofen therapy in ambulatory patients with spasticity. J Neurol. 2006 ; 253: 563-569.
16. Rémy-Néris O., Tiffreau V., Bouilland S., Bussel B. Intrathecal baclofen in subjects with spastic hemiplegia: assessment of the antispastic effect during gait. Arch Phys Med Rehabil. 2003 ; 84: 643-650.
17. The Guarantors of Brain. Aids to the examination of the peripheral nervous system. London, England: Baillière Tindall ; 1986: 1.
18. Lord SE, Halligan PW, Wade DT Visual gait analysis: the development of a clinical assessment and scale. Clin Rehabil. 1998 ; 12: 107-119.
19. Mayr A., Kofler M., Quirbach E., Matzak H., Fröhlich K., Saltuari L. Prospective, blinded, randomized crossover study of gait rehabilitation in stroke patients using the Lokomat gait orthosis. Neurorehabil Neural Repair. 2007 ; 21: 307-314.
20. Albright AL, Thompson K., Carlos S., MInnigh MB Cerebrospinal fluid baclofen concentrations in patients undergoing continuous intrathecal baclofen therapy. Dev Med Child Neurol. 2007 ; 49: 423-425.
21. Faigle JW, Keberle H. The chemistry and kinetics of Lioresal. Postgrad Med J. 1972 ; 48 (Suppl 5). 9-13.
22. Saltuari L., Marosi MJ, Kofler M., Bauer G. Status epilepticus complicating intrathecal baclofen overdose. Lancet. 1992 ; 339: 373-374.
23. Meythaler JM, Guin-Renfroe S., Hadley MN Continuously infused intrathecal baclofen for spastic/dystonic hemiplegia. Am J Phys Med Rehabil. 1999 ; 78: 247-254.
24. Sampson FC, Hayward A., Evans G., Morton R., Collett B. Functional benefits and cost/benefit analysis of continuous intrathecal baclofen infusion for the management of severe spasticity. J Neurosurg. 2002 ; 96: 1052-1057.
25. Zahavi A., Geertzen JH, Middel B., Staal M., Rietman JS Long term effect (more than five years) of intrathecal baclofen on impairment, disability, and quality of life in patients with severe spasticity of spinal origin. J Neurol Neurosurg Psychiatry. 2004 ; 75: 1553-1557.
26. Middel B., Kuipers-Upmeijer H., Bouma J., et al. Effect of intrathecal baclofen delivered by an implanted programmable pump on health related quality of life in patients with severe spasticity. J Neurol Neurosurg Psychiatry. 1997 ; 63: 204-209.
27. McCall TD, MacDonald JD Cervical catheter tip placement for intrathecal baclofen administration. Neurosurgery. 2006 ; 59: 634-639.
28. Kofler M., Matzak H., Saltuari L. The impact of intrathecal baclofen on gastrointestinal function. Brain Inj. 2002 ; 16: 825-836.
29. Steers WD, Meythaler JM, Haworth C., Herrell D., Park TS Effects of acute bolus and chronic continuous intrathecal baclofen on genitourinary dysfunction due to spinal cord pathology. J Urol. 1992 ; 148: 1849-1855.
30. Matzak H., Kofler M., Kiss G., Baldo A., Madersbacher H., Saltuari L. The influence of intrathecally administered baclofen on urinary bladder function in patients with spasticity due to cerebral lesions [Abstracts: 3rd World Congress in Neurological Rehabilitation Venice, Italy]. Neurorehabil Neural Repair. 2002 ; 16: 39.
31. Saltuari L., Baumgartner H., Kofler M., et al. Failure of physostigmine in treatment of acute severe intrathecal baclofen intoxication. N Engl J Med. 1990 ; 322: 1533-1534.
32. Delhaas EM, Brouwers JR Intrathecal baclofen overdose: report of 7 events in 5 patients and review of the literature. Int J Clin Pharmacol Ther Toxicol. 1991 ; 29: 274-280.
33. Kofler M., Kronenberg MF, Rifici C., Saltuari L., Bauer G. Epileptic seizures associated with intrathecal baclofen application. Neurology. 1994 ; 44: 25-27.
34. Hosny A., Simopoulos T., Collins B. Response of intractable post herpetic neuralgia to intrathecal baclofen. Pain Physician. 2004 ; 7: 345-347.
35. Herman RM, D'Luzansky SC, Ippolito R. Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study. Clin J Pain. 1992 ; 8: 338-345.
36. Taira T., Kawamura H., Tanikawa T., Iseki H., Kawabatake H., Takakura K. A new approach to control central deafferentation pain: spinal intrathecal baclofen. Stereotact Funct Neurosurg. 1995 ; 65: 101-105.