The Abdominal-B promoter tethering element mediates promoter-enhancer specificity at the Drosophila bithorax complex

Fly

Volumn 1, Issue 6, 2008, Pages 337-339

  Akbari, Omar S ^a   Schiller, Ben J ^b   Goetz, Sara E ^b   Ho, Margaret C W ^b   Bae, Esther ^c   Drewell, Robert A ^b  

^a UNIVERSITY OF NEVADA   (United States)

^b HARVEY MUDD COLLEGE   (United States)

^c WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

Author keywords

Abdominal B; Bithorax; Cis regulation; Drosophila; Enhancer; Promoter

Indexed keywords

ABD B PROTEINS, DROSOPHILA; ABD-B PROTEINS, DROSOPHILA; BEADEX PROTEIN, DROSOPHILA; DNA; DROSOPHILA PROTEIN; HOMEODOMAIN PROTEIN; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOLOGY; DROSOPHILA; ENHANCER REGION; GENE; GENE EXPRESSION REGULATION; GENETICS; HOMEOBOX; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PRENATAL DEVELOPMENT; PROMOTER REGION; SPECIES DIFFERENCE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DNA; DROSOPHILA; DROSOPHILA PROTEINS; ENHANCER ELEMENTS, GENETIC; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; GENES, INSECT; HOMEODOMAIN PROTEINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; SPECIES SPECIFICITY;

EID: 58149143175     PISSN: 19336934     EISSN: 19336942     Source Type: Journal    
DOI: 10.4161/fly.5607     Document Type: Article

References (15)

1. Duboule D. The rise and fall of Hox gene clusters. Development 2007; 134:2549-60.
2. Lemons D, McGinnis W. Genomic evolution of Hox gene clusters. Science 2006; 313:1918-22.
3. Pearson JC, Lemons D, McGinnis W. Modulating Hox gene functions during animal body patterning. Nature Reviews Genetics 2005; 6:893-904.
4. Lewis EB. A gene complex controlling segmentation in Drosophila. Nature 1978; 276:565-70.
5. Akbari OS, Bae E, Johnsen H, Villaluz A, Wong D, Drewell RA. A novel promoter-tethering element regulates enhancer-driven gene expression at the bithorax complex in the Drosophila embryo. Development 2008; 135:123-31.
6. Akbari OS, Bousum A, Bae E, Drewell RA. Unraveling cis-regulatory mechanisms at the Abdominal-A and Abdominal-B genes in the Drosophila bithorax complex. Dev Biol 2006; 293:294-304.
7. Maeda RK, Karch F. The ABC of the BX-C: The bithorax complex explained. Development 2006; 133:1413-22.
8. Duncan I. The bithorax complex. Annu Rev Genet 1987; 21:285-319.
9. Mihaly J, Hogga I, Gausz J, Gyurkovics H, Karch F. In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element. Development 1997; 124:1809-20.
10. Zhou J, Ashe H, Burks C, Levine M. Characterization of the transvection mediating region of the abdominal-B locus in Drosophila. Development 1999; 126:3057-65.
11. Drosophila Genome Consortium. Evolution of genes and genomes on the Drosophila phylogeny. Nature 2007; 450:203-18.
12. Markstein M, Levine M. Decoding cis-regulatory DNAs in the Drosophila genome. Curr Op Genet Dev 2002; 12:601-6.
13. Lewis EB, Pfeiffer BD, Mathog DR, Celniker SE. Evolution of the homeobox complex in the Diptera. Curr Biol 2003; 13:587-8.
14. Calhoun VC, Stathopoulos A, Levine M. Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex. Proc Natl Acad Sci USA 2002; 99:9243-7.
15. Calhoun VC, Levine, M. Long-range enhancer-promoter interactions in the Scr-Antp interval of the Drosophila Antennapedia complex. Proc Natl Acad Sci USA 2003; 100:9878-83.