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Volumn 67, Issue 1, 2009, Pages 132-134

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL;

EID: 58149125397     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2008.03307.x     Document Type: Letter
Times cited : (10)

References (13)
  • 1
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    • Profiling dihydropyrimidine dehydrogenase deficiency in patients with cancer undergoing 5-fluorouracil/capecitabine therapy
    • Mercier C, Ciccolini J. Profiling dihydropyrimidine dehydrogenase deficiency in patients with cancer undergoing 5-fluorouracil/capecitabine therapy. Clin Colorectal Cancer 2006 6 : 288 96.
    • (2006) Clin Colorectal Cancer , vol.6 , pp. 288-96
    • Mercier, C.1    Ciccolini, J.2
  • 2
    • 29344443013 scopus 로고    scopus 로고
    • Methylation of the DPYD promoter: An alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients
    • Ezzeldin HH, Lee AM, Mattison LK, Diasio RB. Methylation of the DPYD promoter: an alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients. Clin Cancer Res 2005 11 : 8699 705.
    • (2005) Clin Cancer Res , vol.11 , pp. 8699-705
    • Ezzeldin, H.H.1    Lee, A.M.2    Mattison, L.K.3    Diasio, R.B.4
  • 3
    • 0037477777 scopus 로고    scopus 로고
    • Mutational analysis of the human dihydropyrimidine dehydrogenase gene by denaturing high-performance liquid chromatography
    • Fischer J, Schwab M, Eichelbaum M, Zanger UM. Mutational analysis of the human dihydropyrimidine dehydrogenase gene by denaturing high-performance liquid chromatography. Genet Test 2003 7 : 97 105.
    • (2003) Genet Test , vol.7 , pp. 97-105
    • Fischer, J.1    Schwab, M.2    Eichelbaum, M.3    Zanger, U.M.4
  • 5
    • 1942502420 scopus 로고    scopus 로고
    • Rapid identification of dihydropyrimidine dehydrogenase deficiency by using a novel 2-13C-uracil breath test
    • Mattison LK, Ezzeldin H, Carpenter M, Modak A, Johnson MR, Diasio RB. Rapid identification of dihydropyrimidine dehydrogenase deficiency by using a novel 2-13C-uracil breath test. Clin Cancer Res 2004 10 : 2652 8.
    • (2004) Clin Cancer Res , vol.10 , pp. 2652-8
    • Mattison, L.K.1    Ezzeldin, H.2    Carpenter, M.3    Modak, A.4    Johnson, M.R.5    Diasio, R.B.6
  • 6
    • 0037099750 scopus 로고    scopus 로고
    • Simple liquid chromatographic method for the determination of uracil and dihydrouracil plasma levels: A potential pretreatment predictor of 5-fluorouracil toxicity
    • Garg MB, Sevester JC, Sakoff JA, Ackland SP. Simple liquid chromatographic method for the determination of uracil and dihydrouracil plasma levels: a potential pretreatment predictor of 5-fluorouracil toxicity. J Chromatogr B Analyt Technol Biomed Life Sci 2002 774 : 223 30.
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.774 , pp. 223-30
    • Garg, M.B.1    Sevester, J.C.2    Sakoff, J.A.3    Ackland, S.P.4
  • 8
    • 43749109160 scopus 로고    scopus 로고
    • Predicting fluorouracil toxicity: Can we finally do it?
    • Ezzeldin HH, Diasio RB. Predicting fluorouracil toxicity: can we finally do it? J Clin Oncol 2008 26 : 2131 8.
    • (2008) J Clin Oncol , vol.26 , pp. 2131-8
    • Ezzeldin, H.H.1    Diasio, R.B.2
  • 9
    • 0031106817 scopus 로고    scopus 로고
    • Simultaneous determination of dihydrofluorouracil and 5-fluorouracil in plasma by high-performance liquid chromatography
    • Ackland SP, Garg MB, Dunstan RH. Simultaneous determination of dihydrofluorouracil and 5-fluorouracil in plasma by high-performance liquid chromatography. Anal Biochem 1997 246 : 79 85.
    • (1997) Anal Biochem , vol.246 , pp. 79-85
    • Ackland, S.P.1    Garg, M.B.2    Dunstan, R.H.3
  • 11
    • 4043162680 scopus 로고    scopus 로고
    • A simple and rapid high-performance liquid chromatographic (HPLC) method for 5-fluorouracil (5-FU) assay in plasma and possible detection of patients with impaired dihydropyrimidine dehydrogenase (DPD) activity
    • Ciccolini J, Mercier C, Blachon MF, Favre R, Durand A, Lacarelle B. A simple and rapid high-performance liquid chromatographic (HPLC) method for 5-fluorouracil (5-FU) assay in plasma and possible detection of patients with impaired dihydropyrimidine dehydrogenase (DPD) activity. J Clin Pharm Ther 2004 29 : 307 15.
    • (2004) J Clin Pharm Ther , vol.29 , pp. 307-15
    • Ciccolini, J.1    Mercier, C.2    Blachon, M.F.3    Favre, R.4    Durand, A.5    Lacarelle, B.6
  • 13
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    • Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6- dihydrouracil: A case report
    • Bocci G, Danesi R, Allegrini G, Innocenti F, Di Paolo A, Falcone A, Conte PF, Del Tacca M. Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report. Eur J Clin Pharmacol 2002 58 : 593 5.
    • (2002) Eur J Clin Pharmacol , vol.58 , pp. 593-5
    • Bocci, G.1    Danesi, R.2    Allegrini, G.3    Innocenti, F.4    Di Paolo, A.5    Falcone, A.6    Conte, P.F.7    Del Tacca, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.