Association of West Nile virus with lymphohistiocytic proliferative cutaneous lesions in American alligators (Alligator mississippiensis) detected by RT-PCR

Journal of Zoo and Wildlife Medicine

Volumn 39, Issue 4, 2008, Pages 562-566

  Nevarez, Javier G ^a   Mitchell, Mark A ^b   Morgan, Timothy ^a   Roy, Alma ^a   Johnson, April ^c  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c University of Florida College of Veterinary Medicine   (United States)

Author keywords

Alligator mississippiensis; American alligator; Enzyme linked immunosorbent assay; Lymphohistiocytic proliferative syndrome of alligators; Reverse transcriptase polymerase chain reaction; West Nile virus

Indexed keywords

VIRUS ANTIBODY;

ALLIGATOR; ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; CASE CONTROL STUDY; DISEASE CARRIER; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTIOCYTOSIS; ISOLATION AND PURIFICATION; MALE; METHODOLOGY; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY; VIRUS INFECTION; WEST NILE FLAVIVIRUS; ZOO ANIMAL;

ALLIGATORS AND CROCODILES; ANIMALS; ANIMALS, ZOO; ANTIBODIES, VIRAL; CASE-CONTROL STUDIES; DISEASE RESERVOIRS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTIOCYTOSIS; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WEST NILE FEVER; WEST NILE VIRUS;

ALLIGATOR; ALLIGATOR MISSISSIPPIENSIS; ALLIGATORINAE; ANIMALIA; WEST NILE VIRUS;

EID: 58149121061     PISSN: 10427260     EISSN: None     Source Type: Journal    
DOI: 10.1638/2007-0133.1     Document Type: Article

References (18)

1. Anderson, R. C., K. B. Horn, M. P. Hoang, E. Gottlieb, and B. Bennin. 2004. Punctate exanthem of West Nile virus infection: report of 3 cases. J. Am. Acad. Dermatol. 51: 820-823.
2. Asnis, D. S., R. Conetta, A. A. Teixeira, G. Waldman, and B. A. Sampson. 2000. The West Nile virus outbreak of 1999 in New York: the Flushing Hospital experience. Clin. Infect. Dis. 30: 413-418.
3. Cernescu, C., N.-I. Nedelcu, G. Tarei, S. Ruta, and T. F. Tsai. 2000. Continued transmission of West Nile virus to humans in southeastern Romania, 1997-1998. J. Infect. Dis. 181: 710-712.
4. Estival, J. L., F. Skowron, M. Dupin, and P. Combemale. 2001. Primo-infection a virus West-Nile (French). Ann. Dermatol. Venereol. 128: 656-658.
5. Ferguson, D. D., K. Gershman, A. LeBailly, and L. R. Petersen. 2005. Characteristics of the rash associated with West Nile virus fever. Clin. Infect. Dis. 41: 1204-1207.
6. Jacobson, E. R., P. E. Ginn, J. M. Troutman, L. Farina, L. Stark, K. Klenk, K. L. Burkhalter, and N. Komar. 2005. West Nile virus infection in farmed American alligators (Alligator mississippiensis) in Florida. J. Wildl. Dis. 41: 96-106.
7. Jacobson, E. R., A. J. Johnson, J. A. Hernandez, S. J. Tucker, A. P. Dupuis II, R. Stevens, D. Carbonneau, and L. Stark. 2005. Validation and use of an indirect enzyme-linked immunosorbent assay for detection of antibodies to West Nile virus in American alligators (Alligator mississippiensis) in Florida. J. Wildl. Dis. 41: 107-114.
8. Klein, C., I. Kimiagar, L. Pollak, R. Gangelman-Marton, A. Itzhaki, R. Milo, and J. M. Rabey. 2002. Neurological features of West Nile virus infection during the 2000 outbreak in a regional hospital in Israel. J. Neurol. Sci. 200: 63-66.
9. Klenk, K., J. Snow, K. Morgan, R. Bowen, M. Stephens, F. Foster, P. Gordy, S. Beckett, N. Komar, D. Gubler, and M. Bunning. 2004. Alligators as West Nile virus amplifiers. Emerg. Infect. Dis. 10: 2150-2154.
10. Marberg, K., N. Goldblum, V. V. Sterk, W. Jasinkska-Klingberg, and M. A. Klingberg. 1956. The natural history of West Nile fever. Clinical observations during an epidemic in Israel. Am. J. Hyg. 64: 259-269.
11. Nash, D., F. Mostashari, A. Fine, J. Miller, D. O'Leary, K. Murray, A. Huang, A. Rosenberg, A. Greenberg, M. Sherman, S. Wong, and M. Layton. 2001. The outbreak of West Nile virus infection in the New York City area in 1999. N. Engl. J. Med. 344: 1807-1814.
12. Nevarez, J. G., M. A. Mitchell, and M. M. Garner. 2003. Characterizing lymphohistiocytic proliferative syndrome ("PIX") in captive-reared American alligators (Alligator mississippiensis) from Louisiana. Final Report to the Louisiana Department of Wildlife and Fisheries Fur and Refuge Division, New Iberia, Louisiana. 15 pp.
13. Nevarez, J. G., M. A. Mitchell, A. J. Johnson, and N. Kinler. 2007. Establishing an association between West Nile virus exposure and the development of lymphohistiocytic proliferative syndrome of American alligators. J. Herp. Med. Surg. 17: 4-7.
14. Nevarez, J. G., M. A. Mitchell, D. Y. Kim, R. Poston, and H. Lampinen. 2005. West Nile virus in alligator. Alligator mississippiensis, ranches from Louisiana. J. Herp. Med. Surg. 5: 4-9.
15. Pealer, L. N., A. A. Marfin, L. R. Petersen, R. S. Lanciotti, P. L. Page, S. L. Stramer, M. G. Stobierski, K. Signs, B. Newman, H. Kapoor, J. L. Goodman, and M. E. Chamberland. 2003. Transmission of West Nile virus through blood transfusion in the United States in 2002. N. Engl. J. Med. 349: 1236-1245.
16. Sejvar, J. J., M. B. Jaddad, B. C. Tierney, G. L. Campbell, A. A. Marfin, J. A. VanGerpen, A. Fleischauer, A. A. Leis, D. S. Stokic, and L. R. Petersen. 2003. Neurologic manifestations and outcome of West Nile virus infection. JAMA 290: 511-515.
17. Van Belle, G. 2002. Statistical Rules of Thumb. John Wiley & Sons, New York, New York. Pp. 29-51.
18. Wünschmann, A., J. Shivers, J. Bender, L. Carroll. S. Fuller, M. Saggese, A. van Wettere, and P. Redig. 2005. Pathologic and immunohistochemical findings in goshawks (Accipiter gentiles) and great horned owls (Bubo virginianus) naturally infected with West Nile virus. Avian Dis. 49: 252-259.