Amphiphilic poly(hydroxyethylaspartamide) derivative-based micelles as drug delivery systems for ferulic acid

Journal of Drug Targeting

Volumn 17, Issue 1, 2009, Pages 78-88

  Craparo, Emanuela Fabiola ^a   Gennara, Cavallaro ^a   Chiara, Ognibene Maria ^a   Girolamo, Teresi ^a   Luisa, Bondi Maria ^b   Gaetano, Giammona ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR   (Italy)

Author keywords

, poly(N 2 hydroxyethyl) dl aspartamide; Amphiphilic copolymers; Ferulic acid; Polymeric micelles; Rhodamine B base

Indexed keywords

ALIPHATIC AMINE; ALPHA,BETA POLY(N 2 HYDROXYETHYL) DEXTRO LEVO ASPARTAMIDE COPOLYMER; DRUG CARRIER; FERULIC ACID; HEXADECYLAMINE; MACROGOL 2000; PHOSPHATE BUFFERED SALINE; UNCLASSIFIED DRUG;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; CELL STRAIN CACO 2; CELL STRAIN K 562; CHEMICAL MODIFICATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STORAGE; HEMOLYSIS; HUMAN; HUMAN CELL; MACROPHAGE; MICELLE; MOUSE; NONHUMAN; PARTICLE SIZE; PH; PHAGOCYTOSIS; PLASMA; PRIORITY JOURNAL; SKIN FIBROBLAST; ZETA POTENTIAL;

ACTION POTENTIALS; ANIMALS; BUFFERS; CACO-2 CELLS; COUMARIC ACIDS; DRUG DELIVERY SYSTEMS; FLUORESCENT DYES; HUMANS; HYDROGEN-ION CONCENTRATION; K562 CELLS; MACROPHAGES; MICE; MICELLES; PEPTIDES; PHAGOCYTOSIS; PLANT EXTRACTS; RHODAMINES; TECHNOLOGY, PHARMACEUTICAL;

EID: 58149112219     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860802455821     Document Type: Article

References (22)

1. Akagi, T., Baba, M. and Akashi, M. (2007) Preparation of nanoparticles by the self-organization of polymers consisting of hydrophobic and hydrophilic segments: Potential applications. Polymer, 48, pp. 6729-6747.
2. Anselmi, C., Centini, M., Ricci, M., Buonocore, A., Granata, P., Tsuno, T. and Maffei Facino, R (2006) Analytical characterization of a ferulic acid/γ-cyclodextrin inclusion complex. J Pharm Biomed Anal, 40, pp. 875-881.
3. Brigger, I., Morizet, J., Aubert, G., Chacun, H., Terrier-Lacombe, MJ, Couvreur, P. and Vassal, G. (2002) Poly(ethylene glycol)-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting. J Pharmacol Exp Ther, 303, pp. 928-936.
4. Calvo, P., Gouritin, B., Chacun, H., Desmaele, D., D'Angelo, J., Noel, JP, Georgin, D., Fattal, E., Andreux, JP and Couvreur, P. (2001) Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharm Res, 18, pp. 1157-1166.
5. Cavallaro, G., Licciardi, M., Giammona, G., Caliceti, P., Semenzato, A. and Salmaso, S. (2003) Poly(hydroxyethylaspartamide) derivatives as colloidal drug carrier systems. J Control Release, 89, pp. 285-295.
6. Cavallaro, G., Maniscalco, L., Licciardi, M. and Giammona, G. (2004) Tamoxifen-loaded polymeric micelles: Preparation, physico-chemical characterization and in vitro evalutation studies. Macromol Biosci, 4, pp. 1028-1038.
7. Dabholkar, DR, Sawant, RM, Mongayt, DA, Devarajan, PV and Torchilin, VP (2006) Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: Some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. Int J Pharm, 315, pp. 148-157.
8. Francis, MF, Cristea, M. and Winnik, FM (2004) Polymeric micelles for oral drug delivery: Why and how. Pure Appl Chem, 76, pp. 1321-1335.
9. Gao, J., Ming, J., He, B., Fan, Y., Gu, Z. and Zhang, X. (2008) Preparation and characterization of novel polymeric micelles for 9-nitro-20(S)-camptothecin delivery. Eur J Pharm Sci, 34, pp. 85-93.
10. Giammona, G., Carlisi, B. and Palazzo, S. (1987) Reaction of α-β-poly(N-hydroxyethyl)-aspartamide with derivatives of carboxylic acids. J Polym Sci, 25, pp. 2813-2818.
11. Graf, E. (1992) Antioxidant potential of ferulic acid. Free Radic Biol Med, 13, pp. 435-448.
12. Kim, HR, Gil, S., Andrieux, K., Nicolas, V., Appel, M., Chacun, H., Desmaele, D., Taran, F., Georgin, D. and Couvreur, P. (2007) Low-density lipoprotein receptor-mediated endocytosis of PEGylated nanoparticles in rat brain endothelial cells. Cell Mol Life Sci, 64, pp. 356-364.
13. Kim, JH, Kim, YS, Park, K., Kang, E., Lee, S., Nam, HY, Kim, K., Park, JH, Chi, DY, Park, RW, Kim, IS, Choi, K. and Chan Kwon, I (2008) Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy. Biomaterials, 29, pp. 1920-1930.
14. Mendichi, R., Giacometti Schieroni, A, Cavallaro, G., Licciardi, M. and Giammona, G. (2003) Molecular characterization of α, β-poly(N-2hydroxyethyl)-aspartamide derivatives as potential self-assembling copolymers forming polymeric micelles. Polymer, 44, pp. 4871-4879.
15. Ono, K., Hirohata, M. and Yamada, M. (2005) Ferulic acid destabilizes preformed beta-amyloid fibrils in vitro. Biochem Biophys Res Commun, 336, pp. 444-449.
16. Park, JH, Lee, S., Kim, JH, Park, K., Kim, K. and Kwon, IC (2008) Polymeric nanomedicine for cancer therapy. Prog Polym Sci, 33, pp. 113-137.
17. Srinivasan, M., Sudheer, AR and Menon, VP (2007) Ferulic acid: Therapeutic potential through its antioxidant property. J Clin Biochem Nutr, 40, pp. 92-100.
18. Sultana, R., Ravagna, A., Mohmmad-Abdul, H., Calabrese, V. and Butterfield, DA (2005) Ferulic acid ethyl ester protects neurons against amyloid β-peptide(1-42)-induced oxidative stress and neurotoxicity: Relationship to antioxidant activity. J Neurochem, 92, pp. 749-758.
19. Torchilin, VP (2007) Micellar nanocarriers: Pharmaceutical perspectives. Pharm Res, 24, pp. 1-16.
20. Van Butsele, K., Jerome, R. and Jerome, C. (2007) Functional amphiphilic and biodegradable copolymers for intravenous vectorisation. Polymer, 48, pp. 7431-7443.
21. Widemann, TS and Kamel, L. (2002) Examination of the solubilization of drugs by bile salt micelles. J Pharm Sci, 91, pp. 1743-1764.
22. Zhao, Z. and Moghadasian, MH (2008) Chemistry, natural sources, dietary intake and pharmacokinetic properties of ferulic acid: A review. Food Chem, 109, pp. 691-702.