Evaluation of cytotoxic and cytostatic effects in Saccharomyces cerevisiae by poissoner quantitative drop test

Basic and Clinical Pharmacology and Toxicology

Volumn 104, Issue 1, 2009, Pages 71-75

  Poletto, Nadine Paese ^a   Rosado, Joemerson Osório ^a,b   Bonatto, Diego ^a,c  

^a UNIVERSITY OF CAXIAS DO SUL   (Brazil)

^b Pompeia Hospital   (Brazil)

^c Institute of Biotechnology   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; FLUOROURACIL; MESYLIC ACID METHYL ESTER;

ACCURACY; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; NONHUMAN; POISSONER QUANTITATIVE DROP TEST; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SACCHAROMYCES CEREVISIAE; SENSITIVITY ANALYSIS;

4-NITROQUINOLINE-1-OXIDE; CULTURE MEDIA; CYTOSTATIC AGENTS; CYTOTOXINS; FLUOROURACIL; METHYL METHANESULFONATE; PREDICTIVE VALUE OF TESTS; SACCHAROMYCES CEREVISIAE; TOXICITY TESTS;

SACCHAROMYCES CEREVISIAE;

EID: 58149094838     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2008.00336.x     Document Type: Article

References (15)

1. Conconi A, Jager-Vottero P, Zhang X, Beard BC, Smerdon MJ. Mitotic viability and metabolic competence in UV-irradiated yeast cells. Mutat Res 2000 459 : 55 64.
2. Knight AW, Keenan PO, Goddard NJ, Fielden PR, Walmsley RM. A yeast-based cytotoxicity and genotoxicity assay for environmental monitoring using novel portable instrumentation. J Environ Monit 2004 6 : 71 9.
3. Liu Y, Sturley SL. Nutritional genomics in yeast models. Nutrition 2004 20 : 166 72.
4. Armour CD, Lum PY. From drug to protein: using yeast genetics for high-throughput target discovery. Curr Opin Chem Biol 2005 9 : 20 4.
5. Toussaint M, Levasseur G, Gervais-Bird J, Wellinger RJ, Elela SA, Conconi A. A high-throughput method to measure the sensitivity of yeast cells to genotoxic agents in liquid cultures. Mutat Res 2006 606 : 92 105.
6. Lehmann AR, Carr AM. DNA damage, repair and the cell cycle. Trends Cell Biol 1994 4 : 24 6.
7. Saeki K, Okuma E, You A. Recurrent growth factor starvation promotes drug resistance in human leukaemic cells. Br J Cancer 2002 86 : 292 300.
8. Khromov-Borisov NN, Saffi J, Henriques JAP. Perfect order plating: principle and applications. Tech Tips Online 2002 1 : t02638 http://research.bmn.com/tto
9. Han H, Pan Q, Zhang B, Li J, Deng X, Lian Z et al. 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. Toxicology 2007 230 : 151 63.
10. Heres-Pulido ME, Dueñas-García I, Castañeda-Partida L, Sánchez-García A, Contreras-Sousa M, Durán-Díaz A et al. Genotoxicity of tamoxifen citrate and 4-nitroquinoline-1-oxide in the wing spot test of Drosophila melanogaster. Mutagenesis 2004 19 : 187 93.
11. Siddique HR, Chowdhuri DK, Saxena DK, Dhawan A. Validation of Drosophila melanogaster as an in vivo model for genotoxicity assessment using modified alkaline Comet assay. Mutagenesis 2005 20 : 285 90.
12. Pascucci B, Russo MT, Crescenzi M, Bignami M, Dogliotti E. The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells. Nucleic Acids Res 2005 33 : 280 8.
13. Zounková R, Odráska P, Dolezalová L, Hilscherová K, Marsálek B, Bláha L. Ecotoxicity and genotoxicity assessment of cytostatic pharmaceuticals. Environ Toxicol Chem 2007 26 : 2208 14.
14. Seiple L, Jaruga P, Dizdaroglu M, Stivers JT. Linking uracil base excision repair and 5-fluorouracil toxicity in yeast. Nucleic Acids Res 2006 34 : 140 51.
15. Hoskins J, Scott Butler J. Evidence for distinct DNA- and RNA-based mechanisms of 5-fluorouracil cytotoxicity in Saccharomyces cerevisiae. Yeast 2007 24 : 861 70.