Structural and functional characterization of Escherichia coli UMP kinase in complex with its allosteric regulator GTP

Journal of Biological Chemistry

Volumn 283, Issue 51, 2008, Pages 36011-36018

  Meyer, Philippe ^a   Evrin, Cécile ^b,d   Briozzo, Pierre ^a,c,e   Joly, Nathalie ^c   Bârzu, Octavian ^b   Gilles, Anne Marie ^b  

^a LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^b CNRS   (France)

^c CEMAGREF   (France)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e AGROPARISTECH   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOLOGY; BINDING ENERGY; CATALYSTS; CHEMICAL ACTIVATION; CRYSTAL STRUCTURE; ENZYMES; ESCHERICHIA COLI; HYDROGEN; HYDROGEN BONDS; NUCLEIC ACIDS; NUCLEOTIDES; OLIGOMERS; PROTEINS;

ALLOSTERIC ACTIVATORS; ARCHAEAL; BINDING RESIDUES; COOPERATIVITY; E. COLI; FUNCTIONAL CHARACTERIZATIONS; GTP BINDINGS; HEXAMERS; MULTISTEP SYNTHESES; MUTUAL EXCLUSIONS; QUATERNARY STRUCTURES; UMP KINASES;

BINDING SITES;

ADENOSINE TRIPHOSPHATE; ALANINE; GUANOSINE TRIPHOSPHATE; NUCLEOTIDE; PHOSPHOTRANSFERASE; PROTEIN SUBUNIT; URIDINE; URIDINE PHOSPHATE;

ALLOSTERISM; ARTICLE; CRYSTALLIZATION; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION;

ALLOSTERIC REGULATION; AMINO ACID MOTIFS; BINDING SITES; DIMERIZATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GUANOSINE TRIPHOSPHATE; NUCLEOSIDE-PHOSPHATE KINASE; PROTEIN STRUCTURE, QUATERNARY; URACIL NUCLEOTIDES;

ARCHAEA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 58149088061     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802614200     Document Type: Article

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