Adherence to both cotrimoxazole and placebo is associated with improved survival among HIV-infected Zambian children

AIDS and Behavior

Volumn 13, Issue 1, 2009, Pages 33-41

  Walker, A Sarah ^a   Ford, Deborah ^a   Mulenga, Veronica ^b   Thomason, Margaret J ^a   Nunn, Andrew ^a   Chintu, Chifumbe ^b   Gibb, Diana M ^a   Bangsberg, David R ^c  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITY TEACHING HOSPITAL   (Zambia)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adherence; Africa; Cotrimoxazole; HIV

Indexed keywords

COTRIMOXAZOLE; PLACEBO;

ADOLESCENT; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CAREGIVER; CHILD; CHILD CARE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EVENING DOSAGE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION; MAJOR CLINICAL STUDY; MORNING DOSAGE; MORTALITY; PATIENT ATTITUDE; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SURVIVAL RATE; ZAMBIA;

ADOLESCENT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTI-INFECTIVE AGENTS; CAREGIVERS; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; MEDICATION ADHERENCE; PNEUMONIA, PNEUMOCYSTIS; SURVIVAL ANALYSIS; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION; ZAMBIA;

EID: 58149085808     PISSN: 10907165     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10461-008-9382-4     Document Type: Article

References (28)

1. X. Anglaret G. Chene A. Attia S. Toure S. Lafont P. Combe 1999 Early chemoprophylaxis with trimethtoprim-sulphamethoxazole for HIV-1 infected adults in Abidjan, Cote d'Ivoire: A randomised trial The Lancet 353 1463 1468
2. M. Badri G. Maartens R. Wood R. Ehrlich 1999 Co-trimoxazole in HIV-1 infection The Lancet 354 334 335
3. D. R. Bangsberg S. Perry E. D. Charlebois R. A. Clark M. Robertson A. R. Zolopa 2001 Nonadherence to highly active antiretroviral therapy predicts progression to AIDS AIDS 15 1181 1183
4. W. Bikaako-Kajura E. Luyirika D. W. Purcell J. Downing F. Kaharuza J. Mermin 2006 Disclosure of HIV status and adherence to daily drug regimens among HIV-infected children in Uganda AIDS & Behavior 10 S85 S93
5. C. Chintu G. J. Bhat A. S. Walker V. Mulenga F. Sinyinza K. Lishimpi 2004 Cotrimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): A double-blind randomized placebo-controlled trial The Lancet 364 1865 1871
6. L. J. Eldred A. W. Wu R. E. Chaisson R. D. Moore 1998 Adherence to antretroviral and pneumocystis prophylaxis in HIV disease Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology 18 117 125
7. W. M. El-Sadr R. Luskin-Hawk T. M. Yurik J. Walker D. Abrams S. L. John 1999 A randomized trial of daily and thrice-weekly trimethoprim-sulfamethoxazole for the prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected persons Clinical Infectious Diseases 29 775 783
8. J. V. Freeman T. J. Cole S Chinn P. R. M. Jones E. M. White M. A. Preece 1995 Cross sectional stature and weight reference curves for the UK, 1990 Archives of Disease in Childhood 73 17 24
9. Gibb, D. M., Goodall, R. L., Giacomet, V., McGee, L., Compagnucci, A., & Lyall, H., Paediatric European Network for Treatment of AIDS Steering Committee. (2003). Adherence to prescribed antiretroviral therapy in human immunodeficiency virus-infected children in the PENTA 5 trial. Pediatric Infectious Disease Journal, 22, 56-62.
10. K. Grimwade A. W. Sturm A. J. Nunn D. Mbatha D. Zungu C. F. Gilks 2005 Effectiveness of cotrimoxazole on mortality in adults with tuberculosis in rural South Africa AIDS 19 163 168
11. K. R. Hess 1994 Assessing time-by-covariate interactions in proportional hazards regression models using cubic spline functions Statistics in Medicine 13 1045 1062
12. J. L. Jones D. L. Hanson M. S. Dworkin D. L. Alderton P. L. Fleming J. E. Kaplan 1999 Surveillance for AIDS-defining opportunistic illnesses, 1992-1997 Morbidity & Mortality Weekly Report. Surveillance Summaries 48 1 22
13. J. Y. Lee J. W. Kusek P. G. Greene S. Bernhard K. Norris D. Smith 1996 Assessing medication adherence by pill count and electronic monitoring in the African American Study of Kidney Disease and Hypertension (AASK) Pilot Study American Journal of Hypertension 9 719 725
14. Liu, H., Golin, C. E., Miller, L. G., Hays, R. D., Beck, C. K., Sanandaji, S., et al. (2001). A comparison study of multiple measures of adherence to HIV protease inhibitors. Annals of Internal Medicine, 134, 968-977. Erratum in: Annals of Internal Medicine, 136, 175, 2002.
15. S. Mannheimer G. Friedland J. Matts C. Child M. Chesney 2002 The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials Clinical Infectious Diseases 34 1115 1121
16. S. Martin D. K. Elliott-DeSorbo P. L. Wolters M. A. Toledo-Tamula G. Roby S. Zeichner 2007 Patient, caregiver and regimen characteristics associated with adherence to highly active antiretroviral therapy among HIV-infected children and adolescents Pediatric Infectious Disease Journal 26 61 67
17. D. Matsui C. Hermann J. Klein M. Berkovitch N. Olivieri G. Koren 1994 Critical comparison of novel and existing methods of compliance assessment during a clinical trial of an oral iron chelator Journal of Clinical Pharmacology 34 944 949
18. McIntosh, N., Helms, P., & Smyth, R. (2003) Forfar and Arnneil's textbook of paediatrics (6th ed., pp. 576-577). London: Churchill Livingstone.
19. J. J. McNabb D. P. Nicolau J. A. Stoner J. Ross 2003 Patterns of adherence to antiretroviral medications: the value of electronic monitoring AIDS 17 1763 1767
20. J. Mermin J. Lule J. P. Ekwaru S. Malamba R. Downing R. Ransom 2004 Effect of cotrimoxazole prophylaxis on morbidity, mortality, CD4-cell count, and viral load in HIV infection in rural Uganda The Lancet 364 1428 1434
21. E. J. Mills J. B. Nachega D. R. Bangsberg S. Singh B. Rachlis P. Wu 2006 Adherence to HAART; a systematic review of developed and developing nation patient-reported barriers and facilitators PLoS Medicine 3 11 e438
22. A. R. Moss J. A. Hahn S. Perry E. D. Charlebois D. Guzman R. A. Clark 2004 Adherence to highly active antiretroviral therapy in the homeless population in San Francisco: A prospective study Clinical Infectious Diseases 39 1190 1198
23. S. H. Simpson D. T. Eurich S. R. Majumdar R. S. Padwal R. T. Tsuyuki J. Varney 2006 A meta-analysis of the association between adherence to drug therapy and mortality British Medical Journal 333 7557 15
24. A. S. Walker V. Mulenga F. Sinyinza K. Lishimpi A. Nunn C. Chintu 2006 Determinants of survival without antiretroviral therapy after infancy in HIV-1-infected Zambian children in the CHAP trial Journal of Acquired Immune Deficiency Syndromes 42 637 645
25. D. M. Waterhouse K. A. Calzone C. Mele D. E. Brenner 1993 Adherence to oral tamoxifen: A comparison of patient self-report, pill counts and microelectronic monitoring Journal of Clinical Oncology 11 1189 1197
26. Wiktor, S. Z., Sassan-Morroko, M., Grant, A. D., Abouya, L., Karon, J. M., Maurice, C., et al. (1999). Efficacy of trimethoprim-sulphamethoxazole prophylaxis to decrease morbidity and mortality in HIV-1 infected patients with tuberculosis in Abidjan, Cote d'Ivoire: A randomised controlled trial. The Lancet, 353, 1469-1475. Erratum in: The Lancet, 353, 2078, 1999.
27. E. Wood R. S. Hogg B. Yip D. Moore P. R. Harrigan J. S. Montaner 2006 Impact of baseline viral load and adherence on survival of HIV-infected adults with baseline CD4 cell counts > or =200 cells/microl AIDS 20 1117 1123
28. World Health Organization. (2006). Guidelines on co-trimoxazole prophylaxis for HIV-related infections among children, adolescents and adults in resource-limited settings: Recommendations for a public health approach. Retrieved from http://www.womenchildrenhiv.org. Accessed 31 Mar 2008.