Amyloid and transplanted islets

New England Journal of Medicine

Volumn 359, Issue 25, 2008, Pages 2729-2731

  Rickels, Michael R ^a   Collins, Heather W ^a   Naji, Ali ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLIN; AMYLOID; ARGININE; INSULIN;

GRAFT RECIPIENT; HORMONE RELEASE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN RESPONSE; LETTER; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL;

EID: 58049208074     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc082011     Document Type: Letter

References (5)

1. Westermark GT, Westermark P, Berne C, Korsgren O. Wide-spread amyloid deposition in transplanted human pancreatic islets. N Engl J Med 2008;359:977-9.
2. Westermark P, Li ZC, Westermark GT, Leckström A, Steiner DF. Effects of beta cell granule components on human islet amyloid polypeptide fibril formation. FEBS Lett 1996;379:203-6.
3. Janciauskiene S, Eriksson S, Carlemalm E, Ahrén B. Beta cell granule peptides affect human islet amyloid polypeptide (IAPP) fibril formation in vitro. Biochem Biophys Res Commun 1997;236:580-5.
4. Larsson H, Ahrén B. Effects of arginine on the secretion of insulin and islet amyloid polypeptide in humans. Pancreas 1995;11:201-5.
5. Rickels MR, Schutta MH, Markmann JF, Barker CF, Naji A, Teff KL. Beta-cell function following human islet transplantation for type 1 diabetes. Diabetes 2005;54:100-6.