Optimized design of recycle chromatography for separation of a single component from a ternary mixture

Industrial and Engineering Chemistry Research

Volumn 47, Issue 23, 2008, Pages 9601-9610

  Lee, Ju Weon ^a,b   Wankat, Phillip C ^a  

^a Purdue University   (United States)

^b Inha University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SYSTEMS; ADSORBENT PARTICLES; AXIAL DISPERSIONS; CHROMATOGRAPHIC SYSTEMS; COLUMN LENGTHS; DIFFERENT SIZES; LARGE PARTICLES; LINEAR RANGES; MAXIMUM PRODUCTIVITIES; OPTIMIZED DESIGNS; OPTIMUM OPERATING CONDITIONS; SINGLE COMPONENTS; SMALL PARTICLE SIZES; TERNARY MIXTURES; TERNARY SEPARATIONS; TRANSFER RESISTANCES;

ADSORPTION; AMINATION; AMINES; AMINO ACIDS; ATMOSPHERIC TEMPERATURE; BENZENE; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DYES; MIXTURES; ORGANIC ACIDS; PHASE VELOCITY; PHENOLS; SEPARATION;

RECYCLING;

EID: 57949100938     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie800583p     Document Type: Article

References (26)

1. Strube, J.; Haumreisser, S.; Schmidt-Traub, H.; Cchulte, M.; Ditz, R. Comparison of Batch Elution and Continuous Simulated Moving Bed Chromatography. Org. Process Res. Dev. 1998, 2, 305.
2. Grill, C. M.; Miller, L.; Yan, T. Q. Resolution of a Racemic Pharmaceutical Intermediate a Comparison of Preparative HPLC, Steady State Recycling, and Simulated Moving Bed. J. Chromatogr. A 2004, 1026, 101.
3. Kim, J. K.; Wankat, P. C. Designs of Simulated-Moving-Bed Cascades for Quaternary Separations. Ind. Eng. Chem. Res. 2004, 43, 1071.
4. Paredes, G.; Abel, S.; Mazzotti, M.; Morbidelli, M.; Stadler, J. Analysis of a Simulated Moving Bed Operation for Three-Fraction Separations (3F-SMB). Ind. Eng. Chem. Res. 2004, 43, 6157.
5. Borges da Silva, E. A.; Rodrigues, A. E. Design of Chromatographic Multicomponent Separation by a Pseudo-Simulated Moving Bed. AIChE J. 2006, 52, 3794.
6. Broughton, D. B.; Neuzil, R. W.; Pharis, J. M.; Brearley, C. S. The Parex Process for Recovering Paraxylene. Chem. Eng. Prog. 1970, 66, 70.
7. Abunasser, N.; Wankat, P. C.; Kim, Y.-S.; Koo, Y.-M. One-Column Chromatography with Recycle Analogous to a Four-Zone Simulated Moving Bed. Ind. Eng. Chem. Res. 2003, 42, 5268.
8. Abunasser, N.; Wankat, P. C. One-Column Chromatography with Recycle Analogous to Simulated Moving Bed Adsorbers: Analysis and Applications. Ind. Eng. Chem. Res. 2004, 43, 5291.
9. Mota, J. P. B.; Araujo, J. M. M. Single-Column Simulated-MovingBed Process with Recycle Lag. AIChE J. 2005, 57, 1641.
10. Abunasser, N.; Wankat, P. C. Improving the Performance of One Column Analogs to SMBs. AIChE J. 2006, 52, 2461.
11. Hur, J. S.; Wankat, P. C. Chromatographic and SMB Center-Cut Separations of Ternary Mixtures. Sep. Sci. Technol. 2008, 43, 1273.
12. Fukumura, T.; Honda, H.; Kubo, M.; Yonemoto, T. Complete isolation of target solute from multicomponent similar mixture using continuous rotating annular chromatograph with double stage partial recycling of effluent. J. Chem. Technol. Biotechnol. 2005, 80, 712.
13. Zhang, Y.; McConnell, O. Simulated moving columns technique for chiral liquid chromatography. J. Chromatogr. A 2004, 1028, 227.
14. Seidel-Morgenstern, A.; Guiochon, G. Theoretical Study of Recycling in Preparative Chromatography. AIChE J. 1993, 39, 809.
15. Al-Somali, A. M.; Krueger, K. M.; Falkner, J. C.; Colvin, V. L. Recycling Size Exclusion Chromatography for the Analysis and Separation of Nanocrystalline Gold. Anal. Chem. 2004, 76, 5903.
16. Wu, D.-J.; Ma, Z.; Au, B. W.; Wang, N.-H. L. Recovery and Purification of Paclitaxel Using Low-Pressure Liquid Chromatography. AIChE J. 1997, 43, 232.
17. Grill, C. M. Closed-loop recycling with periodic intra-profile injection: a new binary preparative chromatographic technique. J. Chromatogr. A 1998, 767, 101.
18. Lapidus, L.; Amundson, N. R. Mathematics of adsorption in beds. VI. The effect of longitudinal discussion in ion exchange and chromatographic columns. J. Phys. Chem 1952, 56, 984.
19. Dunnebier, G.; Weirich, I.; Klatt, K. U. Computationally efficient dynamic modeling and simulation of simulated moving bed chromatographic process with linear isomerms. Chem Eng. Sci. 1998, 53, 2537.
20. Rhee, H. K.; Aris, R.; Amundson, N. R. First-Order Partial Differential Equations: Theory and Application of Single Equations; Dover Publications: New York, 1986.
21. Chung, S. F.; Wen, C. Y. Longitudinal dispersion of liquid flowing through fixed and fluidized beds. AIChE J. 1968, 14, 857.
22. Bird, R. B.; Stewart, W. E.; Lightfoot, E. N. Transport Phenomena; John Wiley & Sons: New York, 1965.
23. Lisec, O.; Hugo, P.; Seidel-Morgenstern, A. Frontal analysis method to determine competitive adsorption isotherms. J. Chromatogr. A 2001, 908, 19.
24. HUT, J. S.; Wankat, P. C.; Kim, J.-L; Kim, J. K.; Koo, Y.-M. Purification of L-Phenylalanine from a Ternary Amino Acid Mixture Using a Two-Zone SMB/Chromatography Hybrid System. Sep. Sci. Technol. 2007, 42, 911.
25. Adachi, T.; Ando, S.; Watanabe, J. Characterization of synthetic adsorbents with fine particle sizes for preparative-scale chromatographic separation. J. Chromatogr. A 2002, 944, 41.
26. Ganetsos, G.; Barker, P. E. Preparative and Production Scale Chromatography; Marcel Dekker: New York, 1993.